A COMPARATIVE STUDY BETWEEN OSSEOINTEGRATION SUCCESS RATE OF ONE STAGE AND TWO STAGE PROCEDURE IN IMPLANT SURGERY IN BASRAH PROVINCE

AbstractA cohort of 214 patients, who were operated on to insert implants in the mastoid process for the retention of bone-anchored hearing aids and auricular prostheses, was followed-up over a five-year period. About half the group were operated on using the conventional two-stage procedure allowing three to four months for osseointegration. In the second group (one-stage group) the skin penetrating coupling was connected at the time of the implant insertion. The success rate for stable implants was found to be the same in both groups. In the one-stage group four out of 161 implants inserted were lost and in the two stage group three out of 120. The cumulative success rate was also found to be the same. A ‘worst case’ table where patients lost to follow-up, patients who died during the study period, and patients who for some reason left the study is also included. The importance of this ‘worst case’ scenario when follow-up data are presented is discussed.

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10 year institutional experience of use of buccal mucosal grafts for complex urethral reconstruction for varied indications with its outcome

International Surgery Journal ◽

10.18203/2349-2902.isj20204142 ◽

2020 ◽

Vol 7 (10) ◽

pp. 3393

Author(s):

Hemangi R. Athawale ◽

Shivaji B. Mane ◽

Taha Daginawala

Keyword(s):

Success Rate ◽

Surgical Techniques ◽

Postoperative Outcome ◽

Clinical Findings ◽

Sexual Disorders ◽

Urethral Reconstruction ◽

Two Stage ◽

One Stage ◽

Buccal Mucosal Graft ◽

One Stage Reconstruction

Background: The objective of the study was to evaluate long term efficacy and outcome of use of buccal mucosal graft (BMG) for urethral reconstruction in varied urologic conditions in children.Methods: We retrospectively reviewed the medical records of 41 patients from 2009 till 2019 in our institution in which BMG was used for urethral reconstruction. Clinical findings along with surgical techniques used were noted for these patients. Postoperative outcome and complications were evaluated.Results: Mean age was 6.8 years and mean follow up was for 4 years. Out of 41 patients, BMG for substitution urethroplasty was used in 25 cases of hypospadias, 4 cases of urethral stricture, 6 cases of 46 XY disorders of sexual disorders, 4 cases of Y-duplication of urethra, and 2 cases of redo-epispadias repair. 11 patients underwent one stage repairs with a success rate of 63% and 30 patients underwent two stage repair with a success rate of 66%. Analysis and comparison of the outcome in relation to the type of repair, meatal position and number of surgical procedures prior to BMG urethroplasty was statistically insignificant.Conclusions: Buccal mucosa is an ideal graft substitute for urethroplasty. Two stage reconstructions has a slightly higher success rate than one stage reconstruction but the choice of the technique must be based on patients characteristics and on surgeons preference.

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Paper #14 One-stage bilateral total knee replacements: Safety, efficacy and cost-effectiveness. A comparative study to two-stage bilateral and unilateral TKRS

The Journal of Arthroplasty ◽

10.1016/s0883-5403(99)90148-1 ◽

1999 ◽

Vol 14 (2) ◽

pp. 248

Author(s):

Michael H. Huo ◽

Raphael Levin ◽

James F. Wenz ◽

Susan M. McGill ◽

Dennis W. Lennox

Keyword(s):

Cost Effectiveness ◽

Comparative Study ◽

Two Stage ◽

Total Knee Replacements ◽

One Stage ◽

Knee Replacements ◽

Total Knee

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Molecular genetic background of haemophilia A patients with discrepancy between one-stage and two-stage factor VIII assays

Hämostaseologie ◽

10.1055/s-0037-1619100 ◽

2010 ◽

Vol 30 (S 01) ◽

pp. S153-S155

Author(s):

D. Delev ◽

S. Pahl ◽

J. Driesen ◽

H. Brondke ◽

J. Oldenburg ◽

...

Keyword(s):

Factor Viii ◽

Genetic Background ◽

Molecular Genetic ◽

Haemophilia A ◽

Two Stage ◽

One Stage

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Plasma Factor V Activation Is Prevented by Activated Protein C in the Presence of Phospholipid Vesicles, Not Platelets

Thrombosis and Haemostasis ◽

10.1055/s-0038-1651567 ◽

1993 ◽

Vol 69 (02) ◽

pp. 124-129 ◽

Cited By ~ 2

Author(s):

Susan Solymoss ◽

Kim Thi Phu Nguyen

Keyword(s):

Western Blotting ◽

Protein C ◽

Thrombin Generation ◽

Blood Platelets ◽

Activated Protein C ◽

Phospholipid Vesicles ◽

Factor V ◽

Two Stage ◽

One Stage ◽

Plasma Factor

SummaryActivated protein C (APC) is a vitamin K dependent anticoagulant which catalyzes the inactivation of factor Va and VIIIa, in a reaction modulated by phospholipid membrane surface, or blood platelets. APC prevents thrombin generation at a much lower concentration when added to recalcified plasma and phospholipid vesicles, than recalcified plasma and platelets. This observation was attributed to a platelet associated APC inhibitor. We have performed serial thrombin, factor V one stage and two stage assays and Western blotting of dilute recalcified plasma containing either phospholipid vesicles or platelets and APC. More thrombin was formed at a given APC concentration with platelets than phospholipid. One stage factor V values increased to higher levels with platelets and APC than phospholipid and APC. Two stage factor V values decreased substantially with platelets and 5 nM APC but remained unchanged with phospholipid and 5 nM APC. Western blotting of plasma factor V confirmed factor V activation in the presence of platelets and APC, but lack of factor V activation with phospholipid and APC. Inclusion of platelets or platelet membrane with phospholipid enhanced rather than inhibited APC catalyzed plasma factor V inactivation. Platelet activation further enhanced factor V activation and inactivation at any given APC concentration.Plasma thrombin generation in the presence of platelets and APC is related to ongoing factor V activation. No inhibition of APC inactivation of FVa occurs in the presence of platelets.

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Two-Stage Procedure for the Quantitative Determination of Autoprothrombin III Concentration and Some Applications

Thrombosis and Haemostasis ◽

10.1055/s-0038-1655029 ◽

1967 ◽

Vol 18 (01/02) ◽

pp. 198-210 ◽

Cited By ~ 5

Author(s):

Ronald S Reno ◽

Walter H Seegers

Keyword(s):

Prothrombin Time ◽

Factor Vii ◽

Two Stage ◽

Pronounced Increase ◽

One Stage ◽

Assay Procedure ◽

Bovine Plasma ◽

The One ◽

Autoprothrombin C

SummaryA two-stage assay procedure was developed for the determination of the autoprothrombin C titre which can be developed from prothrombin or autoprothrombin III containing solutions. The proenzyme is activated by Russell’s viper venom and the autoprothrombin C activity that appears is measured by its ability to shorten the partial thromboplastin time of bovine plasma.Using the assay, the autoprothrombin C titre was determined in the plasma of several species, as well as the percentage of it remaining in the serum from blood clotted in glass test tubes. Much autoprothrombin III remains in human serum. With sufficient thromboplastin it was completely utilized. Plasma from selected patients with coagulation disorders was assayed and only Stuart plasma was abnormal. In so-called factor VII, IX, and P.T.A. deficiency the autoprothrombin C titre and thrombin titre that could be developed was normal. In one case (prethrombin irregularity) practically no thrombin titre developed but the amount of autoprothrombin C which generated was in the normal range.Dogs were treated with Dicumarol and the autoprothrombin C titre that could be developed from their plasmas decreased until only traces could be detected. This coincided with a lowering of the thrombin titre that could be developed and a prolongation of the one-stage prothrombin time. While the Dicumarol was acting, the dogs were given an infusion of purified bovine prothrombin and the levels of autoprothrombin C, thrombin and one-stage prothrombin time were followed for several hours. The tests became normal immediately after the infusion and then went back to preinfusion levels over a period of 24 hrs.In other dogs the effect of Dicumarol was reversed by giving vitamin K1 intravenously. The effect of the vitamin was noticed as early as 20 min after administration.In response to vitamin K the most pronounced increase was with that portion of the prothrombin molecule which yields thrombin. The proportion of that protein with respect to the precursor of autoprothrombin C increased during the first hour and then started to go down and after 3 hrs was equal to the proportion normally found in plasma.

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