scholarly journals Nickel-Catalyzed Defluorinative Coupling of Aliphatic Aldehydes with Trifluoromethyl Styrenes

2021 ◽  
Author(s):  
Jichao Xiao ◽  
John Montgomery
Keyword(s):  
Nickel Catalyst ◽  
Nickel Complex ◽  
Simple Procedure ◽  
Reactive Intermediates ◽  
Aliphatic Aldehydes ◽  
Zinc Metal ◽  
Mild Conditions ◽  
Substrate Structure ◽  
Bipyridine Ligand ◽  
Low Valent

A simple procedure is reported for the nickel-catalyzed defluorinative alkylation of unactivated aliphatic aldehydes. The process involves the catalytic reductive union of trifluoromethyl styrenes with aldehydes using a nickel complex of a 6,6’-disubstituted bipyridine ligand with zinc metal as the terminal reductant. The protocol is distinguished by its broad substrate scope, mild conditions, and simple catalytic setup. Reaction outcomes are consistent with the intermediacy of an alpha-silyloxy(alkyl)nickel intermediate generated by a low-valent nickel catalyst, silyl electrophile, and the aldehyde substrate. Mechanistic findings with cyclopropanecarboxaldehyde provide insights into nature of the reactive intermediates and illustrate fundamental reactivity differences that are governed by subtle changes in ligand and substrate structure.

Monovalent Nickel Complex Bearing a BulkyN-Heterocyclic Carbene Catalyzes Buchwald–Hartwig Amination of Aryl Halides under Mild Conditions

2011 ◽  
Vol 40 (9) ◽  
pp. 1036-1038 ◽  
Author(s):  
Shinya Nagao ◽  
Taisuke Matsumoto ◽  
Yuji Koga ◽  
Kouki Matsubara
Keyword(s):  
Nickel Complex ◽  
Aryl Halides ◽  
Mild Conditions ◽  
Monovalent Nickel

scholarly journals A simple procedure for synthesis of 3H-quinazolin-4-one hydrazones under mild conditions

2014 ◽  
Vol 18 (6) ◽  
pp. 1022-1027 ◽  
Author(s):  
Mohamed F. Abdel-Megeed ◽  
Mohamed M. Azaam ◽  
Gamal A. El-Hiti
Keyword(s):  
Simple Procedure ◽  
Mild Conditions

Activation and modification of carbon dioxide by redox-active low-valent gallium species

2021 ◽  
Author(s):  
Vladimir Alekseevich Dodonov ◽  
Olga Kushnerova ◽  
Evgeny V Baranov ◽  
Alexander S. Novikov ◽  
Igor Leonidovich Fedushkin
Keyword(s):  
Carbon Dioxide ◽  
Mild Conditions ◽  
Redox Active ◽  
Low Valent

Activation of carbon dioxide in mild conditions by metallylene [(dpp-bian)GaNa(DME)2] (dpp-bian = 1,2-bis[(2,6-di-iso¬propyl-phenyl)-imino]acenaphthene) is described. Further reaction of the activation complex [(dpp-bian)Ga(CO2)2Ga(dpp-bian)][Na(DME)2]2 (2) with diphenylketene, cyclohexylisocyanate, phenylisocyanate leads to elimination...

scholarly journals Efficient alkene hydrosilation with bis(8-quinolyl)phosphine (NPN) nickel catalysts. The dominant role of silyl-over hydrido-nickel catalytic intermediates

2020 ◽  
Vol 11 (19) ◽  
pp. 5043-5051
Author(s):  
Jian Yang ◽  
Verònica Postils ◽  
Michael I. Lipschutz ◽  
Meg Fasulo ◽  
Christophe Raynaud ◽  
...  
Keyword(s):  
Nickel Complex ◽  
Dominant Role ◽  
Nickel Catalysts ◽  
Mild Conditions ◽  
Catalytic Intermediates

A cationic nickel complex of the bis(8-quinolyl)(3,5-di-tert-butylphenoxy)phosphine (NPN) ligand, [(NPN)NiCl]+, is a precursor to efficient catalysts for the hydrosilation of alkenes with hydrosilanes under mild conditions and low catalyst loadings.

Visible-Light-Induced Radical Polynitration of Arylboronic Acids: Synthesis of Polynitrophenols

Synthesis ◽  
2018 ◽  
Vol 50 (15) ◽  
pp. 2891-2896 ◽  
Author(s):  
Jinna Song ◽  
Xihe Bi ◽  
Qi Zhang ◽  
Kaki Raveendra Babu ◽  
Zhouliang Huang
Keyword(s):  
Visible Light ◽  
Aromatic Compounds ◽  
Functional Group ◽  
Simple Procedure ◽  
One Pot ◽  
Arylboronic Acids ◽  
Mild Conditions ◽  
Conventional Methods ◽  
Straightforward Approach

We report a visible light-assisted one-pot method for the synthesis of polynitrophenols through radical tandem hydroxylation and nitration of arylboronic acids by utilizing copper(II) nitrate tri­hydrate as the nitro source. This method features mild conditions, a simple procedure, and good functional group tolerance. Compared to conventional methods, this work provides a straightforward approach for the polynitration of aromatic compounds.

Alum (KAl(SO4)2·12H2O)-Catalyzed, Eco-Friendly, and Efficient One-Pot Synthesis of 2-Arylbenzothiazoles and 2-Arylbenzoxazole in Aqueous Medium

2008 ◽  
Vol 61 (11) ◽  
pp. 905 ◽  
Author(s):  
Shivaji S. Pawar ◽  
Deepak V. Dekhane ◽  
Murlidhar S. Shingare ◽  
Shivaji N. Thore
Keyword(s):  
Ambient Temperature ◽  
Aqueous Medium ◽  
Simple Procedure ◽  
Reaction Yield ◽  
One Pot ◽  
Mild Conditions ◽  
One Pot Synthesis ◽  
Novel Catalyst

Alum (KAl(SO4)2·12H2O) performs as a novel catalyst for the synthesis of 2-arylbenzothiazoles and 2-arylbenzoxazole from o-aminothiophenol and o-aminophenol with various substituted aldehydes in good to excellent isolated yields (85–95%) using water as a solvent at ambient temperature. Several solvents were examined for this reaction; however, in terms of reaction yield and time, water was found to be the optimum solvent. The remarkable advantages offered by this method are an inexpensive and easily available catalyst, a simple procedure, mild conditions, much faster (60–90 min) reactions, and good to excellent yields of products.

Reductive Amination of Aliphatic Carbonyls using Low–valent Titanium Reagent: A Convenient Route to free Primary Amines

2002 ◽  
Vol 2002 (6) ◽  
pp. 253-254 ◽  
Author(s):  
Shyam Rele ◽  
Asoke Banerji ◽  
Sanjay Talukdar
Keyword(s):  
Reductive Amination ◽  
Simple Procedure ◽  
Direct Access ◽  
Primary Amines ◽  
Convenient Route ◽  
Low Valent

A simple procedure for reductive amination of aliphatic carbonyls, giving direct access to free primary amines using low–valent titanium (LVT) reagent has been reported.

H2O as the Sole Hydrogen Source for Ni-Catalyzed Reduction of Alkenes

2019 ◽  
Author(s):  
Yichen Wu ◽  
Tao liu ◽  
Dongping Chen ◽  
Daoming Wang ◽  
Peng Wang
Keyword(s):  
Nickel Catalyst ◽  
Selective Hydrogenation ◽  
Functional Group ◽  
Catalytic Amount ◽  
Mild Conditions ◽  
Water As Solvent ◽  
Direct Hydrogenation ◽  
High Yields

Herein, we reported a nickel catalyzed hydrogenation of alkenes with water as the sole hydrogen source. Employing Zn as reductant and water as solvent in the presence of a catalytic amount of nickel catalyst led to direct hydrogenation of a series of electron-rich and electron-deficient alkenes in high yields. This protocol features unprecedented heterocycle and functional group tolerance under facile and mild conditions. Selective hydrogenation of the substrates containing additional reducible functionalities, such as alkenyl, alkynyl, chloride, ketone, and benzyl group etc, was also realized.

A water reduction process performed by zinc metal under very mild conditions

2010 ◽  
Vol 46 (28) ◽  
pp. 5115 ◽  
Author(s):  
María J. Romero ◽  
Rosa Pedrido ◽  
Ana M. González-Noya ◽  
Miguel Martínez-Calvo ◽  
Guillermo Zaragoza ◽  
...  
Keyword(s):  
Reduction Process ◽  
Zinc Metal ◽  
Water Reduction ◽  
Mild Conditions

Simple procedure for vacant POM-stabilized palladium (0) nanoparticles in water: structural and dispersive effects of lacunary polyoxometalates

RSC Advances ◽  
2014 ◽  
Vol 4 (50) ◽  
pp. 26491-26498 ◽  
Author(s):  
R. Villanneau ◽  
A. Roucoux ◽  
P. Beaunier ◽  
D. Brouri ◽  
A. Proust
Keyword(s):  
Aqueous Solutions ◽  
Palladium Nanoparticles ◽  
Simple Procedure ◽  
Mild Conditions ◽  
Metallic Palladium ◽  
Derivatives Of

Metallic palladium nanoparticles have been generated by hydrogenation in very mild conditions of aqueous solutions of non-organometallic PdII-derivatives of heteropolytungstates.

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