H2O as the Sole Hydrogen Source for Ni-Catalyzed Reduction of Alkenes

2019 ◽  
Author(s):  
Yichen Wu ◽  
Tao liu ◽  
Dongping Chen ◽  
Daoming Wang ◽  
Peng Wang
Keyword(s):  
Nickel Catalyst ◽  
Selective Hydrogenation ◽  
Functional Group ◽  
Catalytic Amount ◽  
Mild Conditions ◽  
Water As Solvent ◽  
Direct Hydrogenation ◽  
High Yields

Herein, we reported a nickel catalyzed hydrogenation of alkenes with water as the sole hydrogen source. Employing Zn as reductant and water as solvent in the presence of a catalytic amount of nickel catalyst led to direct hydrogenation of a series of electron-rich and electron-deficient alkenes in high yields. This protocol features unprecedented heterocycle and functional group tolerance under facile and mild conditions. Selective hydrogenation of the substrates containing additional reducible functionalities, such as alkenyl, alkynyl, chloride, ketone, and benzyl group etc, was also realized.

H2O as the Sole Hydrogen Source for Ni-Catalyzed Reduction of Alkenes

2019 ◽  
Author(s):  
Yichen Wu ◽  
Tao liu ◽  
Dongping Chen ◽  
Daoming Wang ◽  
Peng Wang
Keyword(s):  
Nickel Catalyst ◽  
Selective Hydrogenation ◽  
Functional Group ◽  
Catalytic Amount ◽  
Mild Conditions ◽  
Water As Solvent ◽  
Direct Hydrogenation ◽  
High Yields

Herein, we reported a nickel catalyzed hydrogenation of alkenes with water as the sole hydrogen source. Employing Zn as reductant and water as solvent in the presence of a catalytic amount of nickel catalyst led to direct hydrogenation of a series of electron-rich and electron-deficient alkenes in high yields. This protocol features unprecedented heterocycle and functional group tolerance under facile and mild conditions. Selective hydrogenation of the substrates containing additional reducible functionalities, such as alkenyl, alkynyl, chloride, ketone, and benzyl group etc, was also realized.

p-Toluenesulfonic Acid Coated Natural Phosphate as an Efficient Catalyst for the Synthesis of 2-Substituted Benzimidazole

2018 ◽  
Vol 42 (12) ◽  
pp. 614-617
Author(s):  
Soumia Belkharchach ◽  
Hanane Elayadi ◽  
Hana Ighachane ◽  
Said Sebti ◽  
Mustapha Ait Ali ◽  
...  
Keyword(s):  
Environmentally Friendly ◽  
Catalytic Amount ◽  
Reusable Catalyst ◽  
Efficient Catalyst ◽  
Natural Phosphate ◽  
Mild Conditions ◽  
Toluenesulfonic Acid ◽  
High Yields

2-Substituted benzimidazoles are selectively synthesised in high yields via the condensation of o-phenylenediamine derivatives with aldehyde derivatives using catalytic amount of p-toluenesulfonic acid coated natural phosphate (NP/PTSA) under mild conditions. The use of NP/PTSA as a reusable catalyst makes this process simple, convenient, and environmentally friendly.

Iron(III)/TEMPO-Catalyzed Synthesis of 2,5-Disubstituted 1,3,4-Oxadiazoles by Oxidative Cyclization under Mild Conditions

Synlett ◽  
2017 ◽  
Vol 28 (11) ◽  
pp. 1373-1377 ◽  
Author(s):  
Chengrong Ding ◽  
Guofu Zhang ◽  
Yidong Yu ◽  
Yiyong Zhao ◽  
Xiaoqiang Xie
Keyword(s):  
Functional Group ◽  
Oxidative Cyclization ◽  
Mild Conditions ◽  
Broad Scope ◽  
Oxadiazole Derivatives ◽  
High Yields

A simple and efficient cationic Fe(III)/TEMPO-catalyzed oxidative cyclization of aroyl hydrazones has been developed for the synthesis of 2,5-disubstituted 1,3,4-oxadiazole derivatives. The reaction offers a broad scope, good functional-group tolerance, and high yields under mild conditions in the presence of O2.

Additive- and Oxidant-Free Expedient Synthesis of Benzimidazoles Catalyzed by Cobalt Nanocomposites on N-Doped Carbon

Synlett ◽  
2019 ◽  
Vol 30 (03) ◽  
pp. 319-324 ◽  
Author(s):  
Zhaozhan Wang ◽  
Tao Song ◽  
Yong Yang
Keyword(s):  
Functional Group ◽  
Direct Synthesis ◽  
Biologically Active ◽  
One Pot ◽  
Mild Conditions ◽  
Wide Range ◽  
High Yields

A one-pot direct synthesis of a wide range of biologically active benzimidazoles through coupling of phenylenediamines and aldehydes catalyzed by a highly recyclable nonnoble cobalt nanocomposite was developed. A broad set of benzimidazoles can be efficiently synthesized in high yields and with good functional-group tolerance under additive- and oxidant-free mild conditions. The catalyst can be easily recycled for successive uses, and the process permits gram-scale syntheses of benzimidazoles.

Copper(II)-Catalyzed C–N Coupling of Aryl Halides and N-Nucleophiles Promoted by Quebrachitol or Diethylene Glycol

Synlett ◽  
2019 ◽  
Vol 30 (19) ◽  
pp. 2161-2168
Author(s):  
Fangyu Du ◽  
Qifan Zhou ◽  
Yang Fu ◽  
Yuanguang Chen ◽  
Ying Wu ◽  
...  
Keyword(s):  
Diethylene Glycol ◽  
Functional Group ◽  
Aryl Halides ◽  
Coupling Reactions ◽  
Mild Conditions ◽  
Natural Ligand ◽  
Highly Effective ◽  
High Yields

Herein, we report the natural ligand quebrachitol (QCT) as a promoter for a Cu(II) catalyst, which is highly effective for N-arylation of various amines and related aryl halides. A series of diarylamine derivatives were obtained in high yields by using diethylene glycol (DEG) as both ligand and solvent. The C–N coupling reactions proceed under mild conditions and exhibit good functional group tolerance.

scholarly journals Cs2CO3/[bmim]Br as an Efficient, Green, and Reusable Catalytic System for the Synthesis of N-Alkyl Derivatives of Phthalimide under Mild Conditions

2008 ◽  
Vol 2008 ◽  
pp. 1-4 ◽  
Author(s):  
Alireza Hasaninejad ◽  
Abdolkarim Zare ◽  
Ahmad Reza Moosavi-Zare ◽  
Fatemeh Khedri ◽  
Rahimeh Rahimi ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Catalytic System ◽  
Reaction Times ◽  
Catalytic Amount ◽  
Conjugate Addition ◽  
Reaction Conditions ◽  
Mild Conditions ◽  
Alkyl Derivatives ◽  
High Yields ◽  
Derivatives Of

Aza-conjugate addition of phthalimide to α,β-unsaturated esters efficiently achieves in the presence of catalytic amount of Cs2CO3 and ionic liquid 1-butyl-3-methylimidazolium bromide ([bmim]Br) under mild reaction conditions (70°C) to afford N-alkyl phthalimides in high yields and relatively short reaction times.

Copper-Free Double Silylation of 1,2-Dibromobenzenes Using a Mg/LiCl/DMI System

Synthesis ◽  
2017 ◽  
Vol 49 (11) ◽  
pp. 2495-2500 ◽  
Author(s):  
Tsugio Kitamura ◽  
Rin Yamada ◽  
Keisuke Gondo ◽  
Nobuo Eguchi ◽  
Juzo Oyamada
Keyword(s):  
Functional Group ◽  
Mild Conditions ◽  
Synthetic Utility ◽  
High Yields

The reaction of 1,2-dibromobenzenes with chlorotrimethylsilane efficiently proceeded in the presence of Mg and LiCl in DMI under mild conditions, giving 1,2-bis(trimethylsilyl)benzenes in good to high yields. The reaction of 1,2-dibromobenzenes with chlorodimethylsilane under the same conditions afforded the corresponding 1,2-bis(dimethylsilyl)benzenes in high yields. Functional group transformations of 1,2-bis(trimethylsilyl)benzene were conducted to demonstrate the synthetic utility.

scholarly journals Efficient and selective hydrogenation of amides to alcohols and amines using a well-defined manganese–PNN pincer complex

2017 ◽  
Vol 8 (5) ◽  
pp. 3576-3585 ◽  
Author(s):  
Veronica Papa ◽  
Jose R. Cabrero-Antonino ◽  
Elisabetta Alberico ◽  
Anke Spanneberg ◽  
Kathrin Junge ◽  
...  
Keyword(s):  
Selective Hydrogenation ◽  
Active Catalyst ◽  
Pincer Complexes ◽  
Mild Conditions ◽  
Pincer Complex ◽  
Wide Range ◽  
High Yields

Novel manganese NNP and PNP pincer complexes have been synthesized. The active catalyst allows the efficient hydrogenation of a wide range of amides under relatively mild conditions to afford alcohols and amines in high yields.

Electrochemical Regioselective Bromination of Electron-Rich Aromatic Rings Using n Bu4NBr

Synlett ◽  
2019 ◽  
Vol 30 (11) ◽  
pp. 1313-1316 ◽  
Author(s):  
Wenxia Xie ◽  
Shulin Ning ◽  
Nian Liu ◽  
Ya Bai ◽  
Shutao Wang ◽  
...  
Keyword(s):  
Functional Group ◽  
Tetrabutylammonium Bromide ◽  
Environmentally Friendly ◽  
Aromatic Rings ◽  
Mild Conditions ◽  
High Yields

Electrochemical regioselective bromination of electron-rich aromatic rings using stoichiometric tetrabutylammonium bromide ( n Bu4NBr) has been accomplished under mild conditions. This protocol provides an environmentally friendly and simple way for the construction of C–Br bond in moderate to high yields with wide functional group tolerance.

Citric acid as a trifunctional organocatalyst for thiocyanation of aromatic and heteroaromatic compounds in aqueous media

2012 ◽  
Vol 90 (5) ◽  
pp. 427-432 ◽  
Author(s):  
Ardeshir Khazaei ◽  
Mohammad Ali Zolfigol ◽  
Mohmmad Mokhlesi ◽  
Mahtab Pirveysian
Keyword(s):  
Citric Acid ◽  
Simple Procedure ◽  
Aqueous Media ◽  
Reaction Times ◽  
Catalytic Amount ◽  
Heteroaromatic Compounds ◽  
Mild Conditions ◽  
High Yields

A green and simple procedure for the thiocynation of aromatic and heteroaromatic rings in the presence of a catalytic amount of citric acid in water are described. The reactions proceed in high yields, with short reaction times and under mild conditions.

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