scholarly journals Assessment of Acid Base and Electrolyte Status in Patients with Chronic Kidney Disease

JMS SKIMS ◽  
2013 ◽  
Vol 16 (2) ◽  
pp. 86-89
Author(s):  
Mahrukh Hameed ◽  
Syed Mudassar ◽  
Mosin S Khan ◽  
Nisar Ahmad Wani
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Blood Gas Analysis ◽  
Gas Analysis ◽  
Electrolyte Imbalance ◽  
Common Finding ◽  
Blood Gas ◽  
Acid Base ◽  
Glomerular Diseases ◽  
Nephritic Syndrome

Background: Blood gas measurements are being used to evaluate oxygenation and acid/base status. They are typically ordered if a patient has worsening symptoms of an acid/base imbalance, difficulty in breathing or shortness of breath. Blood gas analysis has been a cornerstone in the management of acutely ill patients with presumed acid/base and electrolyte imbalance. Objective: The aim of this study was to study the blood gases and electrolyte status in patients with chronic kidney disorder. Methods: A prospective study was conducted in the department of Clinical Biochemistry, Sher-I Kashmir Institute of Medical Sciences (SKIMS) Srinagar. A total of 171 patients were included in the study of which 91 were males and 80 were females. The age of the patients ranged between 4 - 80 years. These patients were admitted in the Nephrology ward of SKIMS. Out of these 171 patients included in the study 99 had CKD, 42 had ARF, 11 had metabolic acidosis, 6 had nephritic syndrome, 2 had lupus nephritis and 11 had complications like dysuria, HTN, glomerular diseases etc. The medical history of the patients with CKD was recorded and Samples were obtained for blood gas analysis. Venous samples were obtained for VBG analysis and arterial samples were obtained for ABG analysis. These samples were analysed for determining the blood gas status. Hemoglobin levels and kidney function test were performed manually. Hemoglobin was estimated by cyanmet-hemoglobin method. Urea was estimated by Diacetyl monoxime (DAM) method. Creatinine was estimated by Jaffe’s reaction. Results: CKD patients showed acidosis, hypocapnia and hypoxia. Among electrolytes almost all the patients with CKD had hyponatremia and increased anion gap. Conclusion: It was concluded from the observation that male predominance was seen in chronic kidney disease. Blood gas parameters including pH, PCO2, PO2, HCO3 were found to be deranged in most of the patients with CKD. Among electrolytes sodium was found to be mostly deranged in patients with CKD and Anemia was the most common finding in patients with this disorder. JMS 2013; 16(2):86-89

Comparison of Blood Gas Analysis on Hemodialysis in Patients with Chronic Kidney Diseases

2021 ◽  
Vol 28 (1) ◽  
pp. 55
Author(s):  
Nenden Senina Rindaha ◽  
Sulina Yanti Wibawa ◽  
Yuyun Widaningsih ◽  
Rachmawati A. Muhiddin
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Kidney Diseases ◽  
Blood Gas Analysis ◽  
Gas Analysis ◽  
Rank Test ◽  
Blood Gas ◽  
Metabolic Conditions ◽  
Sigmoid Curve ◽  
Signed Rank Test

Chronic Kidney Disease (CKD) is defined as a renal failure that has lasted for more than three months. Hemodialysis is thetype of kidney replacement therapy that is mostly used, and blood gas analysis can be used to identify this condition. Thisstudy is to compare the blood gas analysis on pre-and post-dialysis in patients with CKD using pH, PaCO , PaO , HCO , SO , 2 2 3 2and BE as markers of improvement in the patients'condition. The population was all patients diagnosed with CKD andhemodialysis at Wahidin Sudirohusodo Hospital, and eligible according to the criteria in this study. The sample size wasdetermined using Federer's calculation, and the statistical analysis using paired T-test and Wilcoxon signed-rank test withα=0.05. Subjects were 34 patients, consisting of 18 females (52.9%) and 16 males (47.1%). Hemodialysis had the mostsignificant impact on the PaO and SaO variables. Relation between PaO and SaO was illustrated in a sigmoid curve. 2 2 2 2Oxygen-bound hemoglobin increased after the first molecule was bound. An almost full PaO pressure will cause a slight 2increase in SaO . Whereas at <90% saturation, a slight decrease in PaO will cause a large decrease in SaO . PaO and SaO 2 2 2 2 2determine cardiac efficiency and the markers for assessing the metabolic conditions of the lungs and heart that correlatewith oxygen. Chronic kidney disease patients experienced improved conditions after undergoing hemodialysis withincreased blood gas values, especially in PaO and SaO .

Acid-Base Balance and Blood Gas Analysis

2018 ◽  
pp. 495-526
Author(s):  
Felice Eugenio Agrò ◽  
Marialuisa Vennari ◽  
Maria Benedetto
Keyword(s):  
Blood Gas Analysis ◽  
Gas Analysis ◽  
Blood Gas ◽  
Acid Base Balance ◽  
Acid Base ◽  
Base Balance

Blood gas analysis

2018 ◽  
Author(s):  
Richard Paul ◽  
Paul Grant
Keyword(s):  
Ph Value ◽  
Fluid Management ◽  
Disease Process ◽  
Blood Gas Analysis ◽  
Underlying Disease ◽  
Gas Analysis ◽  
Blood Gas ◽  
Acid Base ◽  
Electrolyte Disorders ◽  
Arterial Blood

Acid-base homeostasis is vital for the maintenance of normal tissue and organ function, as both acidosis and alkalosis can have harmful and potentially life-threatening effects. Arterial blood gas analysis, combined with routine clinical history and examination, can provide useful information for the management of the critically ill cardiac patient. Most acid-base derangements are reversed by treatment of the underlying disease process, rather than simple correction of the abnormal pH, and prognosis is determined by the nature of the underlying disease, rather than the extent of pH value deviation. Within this chapter, a six-step approach is presented for prompt and accurate acid-base interpretation. Water and electrolyte disorders are common in the intensive cardiac care unit, particularly in patients with cardiac failure. Prompt recognition and treatment is required to prevent cardiovascular and neurological compromise. Therapeutic strategies range from simple electrolyte substitution and fluid management to extracorporeal filtration of excess fluid and electrolytes. These are discussed within this chapter.

Blood gas analysis: acid–base, fluid, and electrolyte disorders

2015 ◽  
Author(s):  
Richard Paul ◽  
Pavlos Myrianthefs ◽  
George Baltopoulos ◽  
Shaun McMaster
Keyword(s):  
Ph Value ◽  
Fluid Management ◽  
Disease Process ◽  
Blood Gas Analysis ◽  
Underlying Disease ◽  
Gas Analysis ◽  
Blood Gas ◽  
Acid Base ◽  
Electrolyte Disorders ◽  
Arterial Blood

Acid-base homeostasis is vital for the maintenance of normal tissue and organ function, as both acidosis and alkalosis can have harmful and potentially life-threatening effects. Arterial blood gas analysis, combined with routine clinical history and examination, can provide useful information for the management of the critically ill cardiac patient. Most acid-base derangements are reversed by treatment of the underlying disease process, rather than simple correction of the abnormal pH, and prognosis is determined by the nature of the underlying disease, rather than the extent of pH value deviation. Within this chapter, a six-step approach is presented for prompt and accurate acid-base interpretation. Water and electrolyte disorders are common in the intensive cardiac care unit, particularly in patients with cardiac failure. Prompt recognition and treatment is required to prevent cardiovascular and neurological compromise. Therapeutic strategies range from simple electrolyte substitution and fluid management to extracorporeal filtration of excess fluid and electrolytes. These are discussed within this chapter.

scholarly journals Association between Acid-Base Balance and Asphyxia in Newborn Infants

2018 ◽  
Vol 34 (1-2) ◽  
pp. 38-43
Author(s):  
Sari Leyli Harahap ◽  
Chairul Adillah Harahap ◽  
Sri Sulastri ◽  
Chairul Yoel ◽  
Noersida Raid
Keyword(s):  
Apgar Score ◽  
Newborn Infants ◽  
Blood Gas Analysis ◽  
Gas Analysis ◽  
Blood Gas ◽  
Acid Base Balance ◽  
Acid Base ◽  
Apgar Scores ◽  
Arterial Blood ◽  
Base Balance

We performed a prospective study on the association between acid-base balance and asphyxta based on Apgar scores in 45 newborn babies admitted to the Division of Perinatology, Pirngadi Hospital, Medan, from January 1 to February 28, 1993. Blood gas analysis was done on blood obtained from umbilical artery. Based on 1st and 5th minutes Apgar scores, 40 (88.9%) and 21 babies (46.7%}, respectively, had asphyxia. Relation to acid-base balance was determined with the sensitivity of the 5th minute Apgar score in predicting acidotic states. It was found that Apgar score had sensitivity of 57.7% and specificity of 68.4% in predicting the acidotic states. Apgar score of > 7 was unable to. exclude the possible acidosis in 45% of cases (negative predictive value 54.1%). Gestational age had no influence on Apgar Scores. Apgar score was more sensitive to eliminate suspected acidosis in term neonates than in preterms. We recommend to perform umbilical arterial blood gas analysis to determine acidotic state in high risk newborn infants.

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