scholarly journals Current Biological Strategies to Enhance Surgical Treatment for Rotator Cuff Repair

2021 ◽  
Vol 9 ◽  
Author(s):  
Cheng Zhang ◽  
Jun Wu ◽  
Xiang Li ◽  
Zejin Wang ◽  
Weijia William Lu ◽  
...  
Keyword(s):  
Stem Cells ◽  
Growth Factors ◽  
Rotator Cuff ◽  
Rotator Cuff Tear ◽  
Rotator Cuff Repair ◽  
Platelet Rich Plasma ◽  
Healing Process ◽  
Cuff Tear ◽  
Research Perspectives ◽  
Cuff Repair

Rotator cuff tear is one of the most common shoulder problems encountered by orthopedic surgeons. Due to the slow healing process and high retear rate, rotator cuff tear has distressed millions of people all around the world every year, especially for the elderly and active athletes. This disease significantly impairs patients’ motor ability and reduces their quality of life. Besides conservative treatment, open and arthroscopic surgery contributes a lot to accelerate the healing process of rotator cuff tear. Currently, there are many emerging novel treatment methods to promote rotator cuff repair. A variety of biological stimulus has been utilized in clinical practice. Among them, platelet-rich plasma, growth factors, stem cells, and exosomes are the most popular biologics in laboratory research and clinical trials. This review will focus on the biologics of bioaugmentation methods for rotator cuff repair and tendon healing, including platelet-rich plasma, growth factors, exosomes and stem cells, etc. Relevant studies are summarized in this review and future research perspectives are introduced.

scholarly journals The Influence of Rotator Cuff Tear Size and Repair Technique on Creation and Management of Dog Ear Deformities in a Transosseous Equivalent Rotator Cuff Repair Model

2013 ◽  
Vol 22 (10) ◽  
pp. e31-e32
Author(s):  
Lauren H. Redler ◽  
Ian R. Byram ◽  
Timothy J. Luchetti ◽  
Ying Lai Tsui ◽  
Todd C. Moen ◽  
...  
Keyword(s):  
Rotator Cuff ◽  
Rotator Cuff Tear ◽  
Rotator Cuff Repair ◽  
Cuff Tear ◽  
Repair Technique ◽  
Cuff Repair ◽  
Tear Size

scholarly journals Superior Capsular Reconstruction With Superimposition of Rotator Cuff Repair for Massive Rotator Cuff Tear

2017 ◽  
Vol 6 (5) ◽  
pp. e1775-e1779 ◽  
Author(s):  
George Sanchez ◽  
Jorge Chahla ◽  
Gilbert Moatshe ◽  
Márcio B. Ferrari ◽  
Nicholas I. Kennedy ◽  
...  
Keyword(s):  
Rotator Cuff ◽  
Rotator Cuff Tear ◽  
Rotator Cuff Repair ◽  
Massive Rotator Cuff Tear ◽  
Cuff Tear ◽  
Superior Capsular Reconstruction ◽  
Cuff Repair

scholarly journals Depression increases the risk of rotator cuff tear and rotator cuff repair surgery: A nationwide population-based study

PLoS ONE ◽  
2019 ◽  
Vol 14 (11) ◽  
pp. e0225778 ◽  
Author(s):  
Liang-Tseng Kuo ◽  
Hong-Ming Chen ◽  
Pei-An Yu ◽  
Chi-Lung Chen ◽  
Wei-Hsiu Hsu ◽  
...  
Keyword(s):  
Rotator Cuff ◽  
Rotator Cuff Tear ◽  
Rotator Cuff Repair ◽  
Population Based ◽  
Population Based Study ◽  
Cuff Tear ◽  
Cuff Repair

scholarly journals Tissue Engineering for Rotator Cuff Repair: An Evidence-Based Systematic Review

2012 ◽  
Vol 2012 ◽  
pp. 1-11 ◽  
Author(s):  
Nicola Maffulli ◽  
Umile Giuseppe Longo ◽  
Mattia Loppini ◽  
Alessandra Berton ◽  
Filippo Spiezia ◽  
...  
Keyword(s):  
Systematic Review ◽  
Tissue Engineering ◽  
Stem Cells ◽  
Rotator Cuff ◽  
Rotator Cuff Repair ◽  
Platelet Rich Plasma ◽  
Control Group ◽  
Tissue Engineering Application ◽  
Significant Difference ◽  
Cuff Repair

The purpose of this systematic review was to address the treatment of rotator cuff tears by applying tissue engineering approaches to improve tendon healing, specifically platelet rich plasma (PRP) augmentation, stem cells, and scaffolds. Our systematic search was performed using the combination of the following terms: “rotator cuff”, “shoulder”, “PRP”, “platelet rich plasma”, “stemcells”, “scaffold”, “growth factors”, and “tissue engineering”. No level I or II studies were found on the use of scaffolds and stem cells for rotator cuff repair. Three studies compared rotator cuff repair with or without PRP augmentation. All authors performed arthroscopic rotator cuff repair with different techniques of suture anchor fixation and different PRP augmentation. The three studies found no difference in clinical rating scales and functional outcomes between PRP and control groups. Only one study showed clinical statistically significant difference between the two groups at the 3-month followup. Any statistically significant difference in the rates of tendon rerupture between the control group and the PRP group was found using the magnetic resonance imaging. The current literature on tissue engineering application for rotator cuff repair is scanty. Comparative studies included in this review suggest that PRP augmented repair of a rotator cuff does not yield improved functional and clinical outcome compared with non-augmented repair at a medium and long-term followup.

scholarly journals Does Rotator Cuff Repair Improve Psychologic Status and Quality of Life in Patients With Rotator Cuff Tear?

2015 ◽  
Vol 473 (11) ◽  
pp. 3494-3500 ◽  
Author(s):  
Chul-Hyun Cho ◽  
Kwang-Soon Song ◽  
Ilseon Hwang ◽  
Jon J. P. Warner
Keyword(s):  
Quality Of Life ◽  
Rotator Cuff ◽  
Rotator Cuff Tear ◽  
Rotator Cuff Repair ◽  
Cuff Tear ◽  
Cuff Repair
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