scholarly journals Magnetic Microdimer as Mobile Meter for Measuring Plasma Glucose and Lipids

Author(s):  
Shimin Yu ◽  
Zhongqi Sun ◽  
Zhanxiang Zhang ◽  
Haoran Sun ◽  
Lina Liu ◽  
...  

With the development of designed materials and structures, a wide array of micro/nanomachines with versatile functionalities are employed for specific sensing applications. Here, we demonstrated a magnetic propelled microdimer-based point-of-care testing system, which can be used to provide the real-time data of plasma glucose and lipids relying on the motion feedback of mechanical properties. On-demand and programmable speed and direction of the microdimers can be achieved with the judicious adjustment of the external magnetic field, while their velocity and instantaneous postures provide estimation of glucose, cholesterol, and triglycerides concentrations with high temporal accuracy. Numerical simulations reveal the relationship between motility performance and surrounding liquid properties. Such technology presents a point-of-care testing (POCT) approach to adapt to biofluid measurement, which advances the development of microrobotic system in biomedical fields.

2015 ◽  
Vol 446 ◽  
pp. 263-266 ◽  
Author(s):  
Carlos Eduardo dos Santos Ferreira ◽  
Carolina Nunes França ◽  
Cassyano Januário Correr ◽  
Márcia L. Zucker ◽  
Adagmar Andriolo ◽  
...  

2009 ◽  
Author(s):  
Albrecht Brandenburg ◽  
Franziska Curdt ◽  
Joerg Nestler ◽  
Thomas Otto ◽  
Kai Wunderlich ◽  
...  

Lab on a Chip ◽  
2020 ◽  
Vol 20 (14) ◽  
pp. 2549-2561 ◽  
Author(s):  
Martin Schulz ◽  
Silvia Calabrese ◽  
Florian Hausladen ◽  
Holger Wurm ◽  
Dominik Drossart ◽  
...  

Automated point-of-care testing system for rapid single cell detection of MRSA directly from nasal swab samples.


The Analyst ◽  
2013 ◽  
Vol 138 (9) ◽  
pp. 2558 ◽  
Author(s):  
Woochang Lee ◽  
Jaeyeon Jung ◽  
Young Ki Hahn ◽  
Sang Kyu Kim ◽  
Yeolho Lee ◽  
...  

2005 ◽  
Vol 21 (3) ◽  
pp. 426-432 ◽  
Author(s):  
Masaki Yamaguchi ◽  
Shigenori Kambe ◽  
Takashi Eto ◽  
Masaru Yamakoshi ◽  
Takuji Kouzuma ◽  
...  

Critical Care ◽  
2012 ◽  
Vol 16 (S3) ◽  
Author(s):  
H Kim ◽  
ES Yoon ◽  
S Ho ◽  
SW Oh ◽  
EY Choi

Angiology ◽  
2009 ◽  
Vol 60 (3) ◽  
pp. 358-361 ◽  
Author(s):  
Alexander D. Douglas ◽  
Jo Jefferis ◽  
Rishi Sharma ◽  
Rachel Parker ◽  
Ashok Handa ◽  
...  

Introduction Patients on intravenous heparin require regular activated partial thromboplastin time monitoring. Laboratory-based activated partial thromboplastin time assays necessitate a delay between blood sampling and dose adjustment. Point-of-care testing could permit immediate dose adjustments, potentially enabling tighter control of anticoagulation. Aim To assess equivalence of activated partial thromboplastin time measured by conventional laboratory assay and by a novel proprietary point-of-care testing system (Hemochron Response, ITC, Thoratec Corporation, Edison, NJ) among surgical ward patients on intravenous heparin. Methods A total of 39 blood samples from patients on intravenous heparin were tested with both laboratory and point-of-care assays. Assay equivalence was assessed by Bland-Altman analysis. Results. Point-of-care measurements exceeded laboratory activated partial thromboplastin time by a mean of 15 seconds (standard deviation 19). In 19 cases (49%), the point-of-care measurement would have resulted in different heparin dosing from the laboratory activated partial thromboplastin time. Conclusions The Hemochron Response system is not sufficiently accurate for routine ward use compared with laboratory activated partial thromboplastin time assays.


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