scholarly journals Evaluation of Choroidal Thickness Using Optical Coherent Tomography: A Review

2021 ◽  
Vol 8 ◽  
Author(s):  
Rui Xie ◽  
Bingjie Qiu ◽  
Jay Chhablani ◽  
Xinyuan Zhang
Keyword(s):  
Optical Coherence Tomography ◽  
Choroidal Thickness ◽  
Enhanced Depth Imaging ◽  
Swept Source ◽  
Depth Imaging ◽  
Spectral Domain Oct ◽  
Tremendous Progress ◽  
Measurement Methodology ◽  
Swept Source Oct ◽  
Spectrum Disorders

The choroid is the main source of blood and nourishment supply to the eye. The dysfunction of the choroid has been implicated in various retinal and choroidal diseases. The identification and in-depth understanding of pachychoroid spectrum disorders are based on the tremendous progress of optical coherence tomography (OCT) technology in recent years, although visibility of choroid is challenging in the era of the time or spectral domain OCT. The recent rapid revolution of OCTs, such as the enhanced depth imaging OCT and the swept-source OCT, has greatly contributed to the significant improvement in the analysis of the morphology and physiology of the choroid precisely, especially to the choroid–scleral boundary and vasculature. The present review highlights the recently available evidence on the measurement methodology and the clinical significance of choroidal thickness in retinal or choroidal disorders.

scholarly journals Optimized imaging of the suprachoroidal space with swept-source OCT

2019 ◽  
Vol 16 (4) ◽  
pp. 323-328
Author(s):  
Joel Hanhart ◽  
Rozenman Yaacov
Keyword(s):  
Optical Coherence Tomography ◽  
Enhanced Depth Imaging ◽  
Swept Source ◽  
Depth Imaging ◽  
New Approach ◽  
Suprachoroidal Space ◽  
Outer Border ◽  
Minimum Age ◽  
Swept Source Oct

Purpose: To compare enhanced depth imaging (EDI) and non-EDI swept source optical coherence tomography (SS-OCT) in their ability to capture the suprachoroidal space (SCS). Materials and methods: Twenty volunteers with a minimum age of 18 years without any ocular pathology and refractive error below Å} 2 diopters underwent SS-OCT foveal scanning, with and without EDI. Masked averaged B-scan lines were analyzed for presence of the SCS. When the SCS was seen, the percentage of the scan on which this structure could be unequivocally observed was measured. Scores obtained from the images taken with or without EDI were then compared. Results: Thirty-seven eyes were analysed, since three eyes of three different patients were eliminated, as the outer border of the choroid was insufficiently delineated with both modalities. The SCS was not detected at all on 14 pictures (37.8%) obtained by non-EDI SS-OCT and 9 pictures (24.3%) obtained by EDI SS-OCT. When the SCS was detected with both modalities, it was observable on 27.2+/-24.2% of the scan without EDI and 40.4+/-30.3 of the scan with EDI (p < .001) Conclusions: EDI SS-OCT enables a more frequent and extensive visualization of the suprachoroidal space than non-EDI SS-OCT. This new approach could be considered as the most accurate modality to currently visualize the SCS in vivo.

scholarly journals Choroidal thickness in eyes with different degrees of myopia

2013 ◽  
Vol 6 (4) ◽  
pp. 34-38 ◽  
Author(s):  
Yuriy Sergeyevich Astakhov ◽  
Svetlana Georgiyevna Belekhova
Keyword(s):  
Optical Coherence Tomography ◽  
Negative Correlation ◽  
Choroidal Thickness ◽  
Healthy People ◽  
Enhanced Depth Imaging ◽  
Control Group ◽  
Depth Imaging ◽  
Subfoveal Choroidal Thickness ◽  
Imaging Optical Coherence Tomography ◽  
Spectralis Oct

66 healthy people (124 eyes) with different degrees of myopia and emmetropia were examined using enhanced depth imaging optical coherence tomography (EDI-OCT) using the “Spectralis OCT”. It was found that the choroid in subjects with medium and high degrees of myopia was significantly thinner than that in the control group. In the study, a negative correlation was found between the subfoveal choroidal thickness and the degree of myopia (r = -0.75, p < 0.0001). It was also found that the subfoveal choroidal thickness decreased for each diopter of myopia by approximately 18.03 μm.

scholarly journals Optical Coherence Tomography Characteristics of the Choroid Underlying Congenital Hypertrophy of the Retinal Pigment Epithelium

2020 ◽  
Vol 6 (4) ◽  
pp. 238-243
Author(s):  
Jasmine H. Francis ◽  
Ethan K. Sobol ◽  
Molly Greenberg ◽  
Robert Folberg ◽  
David H. Abramson
Keyword(s):  
Optical Coherence Tomography ◽  
Retinal Pigment Epithelium ◽  
Choroidal Thickness ◽  
Retinal Thickness ◽  
Pigment Epithelium ◽  
Retinal Pigment ◽  
Enhanced Depth Imaging ◽  
Optical Coherence ◽  
Depth Imaging ◽  
Congenital Hypertrophy

Purpose: This study evaluates and characterizes the choroid underlying congenital hypertrophy of the retinal pigment epithelium (CHRPE). Methods: Retrospective observational study of CHRPE at least 2 mm in diameter. Choroidal vascular architecture was qualitatively examined. Choroidal thickness was measured by 2 independent observers using enhanced depth imaging spectral domain optical coherence tomography. Results: Forty-six eyes of 46 patients with CHRPE were included. Thirty-two lesions had imaging sufficient for analysis. Haller’s layer was healthy in 18 (56%), thin in 13 (41%), and absent in 1 (2%). Sattler’s layer was atrophic in 30 (94%), and choriocapillaris was atrophic in 31 (97%). CHRPE with thinned Haller’s layer had significantly larger diameter. The mean sub-CHRPE choroidal thickness was 82.4 ± 7.9 µm, compared to a thickness of 148.4 ± 9.6 µm in the normal adjacent choroid (p < 0.0001). Mean retinal thickness overlying the CHRPE was 77.3 ± 4.3 µm, compared to a retinal thickness of 137.8 ± 2.9 µm overlying the normal adjacent choroid (p < 0.0001). Sub-CHRPE choroidal thickness was a mean of 56.2 ± 3.1% of the adjacent normal choroidal thickness. Conclusion: The underlying choroid CHRPE is thinner than the adjacent normal choroid. All layers of the choroid can be thin with a preference of the inner Sattler’s and choriocapillaris layers.

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