scholarly journals Transient Hypothyroidism During Lactation Alters the Development of the Corpus Callosum in Rats. An in vivo Magnetic Resonance Image and Electron Microscopy Study

2020 ◽  
Vol 14 ◽  
Author(s):  
Federico Salas-Lucia ◽  
Jesús Pacheco-Torres ◽  
Susana González-Granero ◽  
José Manuel García-Verdugo ◽  
Pere Berbel
1984 ◽  
Vol 17 (2) ◽  
pp. 89-93 ◽  
Author(s):  
Thaisa de Almeida Maria ◽  
Leny de Sousa Filardi ◽  
Zigman Brener

An electron microscopy study shows that the administration of a single dose (500 mg/kg, p.o.) of 2-amino-5-(1-methyl-5-nitro-2-imidazolyl)-1, 3, 4-thiadiazole induces in mice infected with Trypanosoma cruzi results in degenerative lesions of the intracellular stages. Ultrastructural alterations are detected as early as 6 hours after the drug administration and destruction of the parasites occurs within 18 - 36 hours. Trypomastigotes are cleared from the bloodstream 4 to 6 hours after treatment. The combined effect on both developmental stages is apparently responsible for the in vivo ejfects of this drug which is the most active drug ever tested in our laboratory in experimental Chagas' disease.


2002 ◽  
Vol 259 (7) ◽  
pp. 362-364 ◽  
Author(s):  
Sebahattin Cüreoğlu ◽  
Murat Akkuş ◽  
Üstün Osma ◽  
Mehmet Yaldiz ◽  
Faruk Oktay ◽  
...  

2003 ◽  
Vol 80 (4) ◽  
pp. 419-423 ◽  
Author(s):  
Eddy Esselink ◽  
Henrie van Aalst ◽  
Manuelle Maliepaard ◽  
Thijs M. H. Henderson ◽  
Niko L. L. Hoekstra ◽  
...  

Eye ◽  
1989 ◽  
Vol 3 (5) ◽  
pp. 597-605 ◽  
Author(s):  
Nicholas A P Brown ◽  
Gijs Vrensen ◽  
G Adrien Shun-Shin ◽  
Ben Willekens

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