scholarly journals Excitatory Impact of Dental Occlusion on Dorsal Motor Nucleus of Vagus

2021 ◽  
Vol 15 ◽  
Author(s):  
Xin Liu ◽  
Minghong Shi ◽  
Haotian Ren ◽  
Mianjiao Xie ◽  
Chunkui Zhang ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Postprandial Blood Glucose ◽  
Dental Occlusion ◽  
Motor Nucleus ◽  
Neuroendocrine Response ◽  
Dorsal Motor Nucleus ◽  
Postprandial Blood Glucose Level ◽  
Glucagon And Insulin

Neurons in the trigeminal mesencephalic nucleus (Vme) have axons that branch peripherally to innervate the orofacial region and project centrally to several motor nuclei in brainstem. The dorsal motor nucleus of vagus nerve (DMV) resides in the brainstem and takes a role in visceral motor function such as pancreatic exocrine secretion. The present study aimed to demonstrate the presence of Vme–DMV circuit, activation of which would elicit a trigeminal neuroendocrine response. A masticatory dysfunctional animal model termed unilateral anterior crossbite (UAC) model created by disturbing the dental occlusion was used. Cholera toxin B subunit (CTb) was injected into the inferior alveolar nerve of rats to help identify the central axon terminals of Vme neurons around the choline acetyltransferase (ChAT) positive motor neurons in the DMV. The level of vesicular glutamate transporter 1 (VGLUT1) expressed in DMV, the level of acetylcholinesterase (AChE) expressed in pancreas, the level of glucagon and insulin expression in islets and serum, and the blood glucose level were detected and compared between UAC and the age matched sham-operation control mice. Data indicated that compared with the controls, there were more CTb/VGLUT1 double labeled axon endings around the ChAT positive neurons in the DMV of UAC groups. Mice in UAC group expressed a higher VGLUT1 protein level in DMV, AChE protein level in pancreas, glucagon and insulin level in islet and serum, and higher postprandial blood glucose level, but lower fasting blood glucose level. All these were reversed at 15-weeks when UAC cessation was performed from 11-weeks (all, P < 0.05). Our findings demonstrated Vme–DMV circuit via which the aberrant occlusion elicited a trigeminal neuroendocrine response such as alteration in the postprandial blood glucose level. Dental occlusion is proposed as a potential therapeutic target for reversing the increased postprandial glucose level.

scholarly journals Effect of Vietnamese Common Diet on Postprandial Blood Glucose Level in Adult Females

2007 ◽  
Vol 53 (3) ◽  
pp. 247-252 ◽  
Author(s):  
Pei-Ying LIN ◽  
Bui Thi NHUNG ◽  
Nguyen Cong KHAN ◽  
Nobuko SARUKURA ◽  
Daisuke KUNII ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Postprandial Blood Glucose ◽  
Adult Females ◽  
Postprandial Blood Glucose Level

scholarly journals CORRELATION BETWEEN BLOOD GLUCOSE LEVEL AND THINKING CONCENTRATION

2017 ◽  
Vol 52 (3) ◽  
pp. 214
Author(s):  
Putri Itonami Gaol Marbun ◽  
Tengku Helvi Mardiani
Keyword(s):  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Postprandial Blood Glucose ◽  
Trail Making Test ◽  
Complex Thinking ◽  
Specific Memory ◽  
Postprandial Blood Glucose Level ◽  
Trail Making ◽  
Glucose Meter

Cognition function specifically about thinking concentration has not much yet been studied. Society view shown that glucose has role thinking quality. Few studies shown that glucose has role in specific memory quality but not in complex thinking. This study purpose to see correlation between blood glucose level with thinking concentration before eating (preprandial), after eating (postprandial), and the effect of blood glucose rise on thinking concentration. Subjects that accomplished study’s requirement were recruited until forty six people and were followed within thirty minutes. Blood Glucose level was measured by glucose meter at initial admission, thinking concentration were measured with trail making test at initial admission, and compared after eating on the thirtieth minute. Descriptive analytic shown that preprandial blood glucose level in all subject is 55-119 mg/dl with 98.2 mg/dl mean. Postprandial blood glucose level in all subject is 103-171 mg/dl with 134.5 mg/dl mean. Preprandial thinking concentration in all subject is 28-93 seconds with 56.42 seconds mean. Postprandial thinking concentration in all subject is 24-73 seconds with 47.5 seconds mean. Correlation analysis showed that no significance between preprandial blood glucose level and thinking concentration (p = 0.556), postprandial blood glucose level and thinking concentration (p = 0.533), and increase in blood glucose and thinking concentration (p= 0.928). In conclusion there is no significant correlation between blood glucose level and thinking concentration.

Jew's Mellow Leaves (Corchorus olitorius) Suppress Elevation of Postprandial Blood Glucose Levels in Rats and Humans

2005 ◽  
Vol 75 (1) ◽  
pp. 39-46 ◽  
Author(s):  
Satoshi Innami ◽  
Hiroshi Ishida ◽  
Kahoru Nakamura ◽  
Mika Kondo ◽  
Kimiko Tabata ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Glucose Solution ◽  
Postprandial Blood Glucose ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Intestinal Membrane ◽  
Freeze Dried ◽  
Postprandial Blood Glucose Level

The study was performed to explore the suppressive effect of Jew's mellow leaves (JML) on postprandial blood glucose levels in rats and humans. A soluble dietary fiber (SDF) was extracted from the freeze-dried JML powder. An elevation of the postprandial blood glucose level in rats given 1% or 2% JML-SDF solution orally together with 20% glucose solution was significantly suppressed as compared with that observed in the control rats given only glucose solution. When seven healthy young male adults ingested 225 mL of JML mixed juice containing 15 g of freeze-dried powder with 75 g of glucose in the fasting state in the morning, the elevation of the postprandial blood glucose level was significantly suppressed as compared with the control subjects. The diffusion rate of glucose and the permeation rate of glucose in the cultured Caco-2 cells were both significantly reduced by the addition of appropriate amounts of JML-SDF when compared to the controls. These results indicate that the effective substance in JML for suppressing blood glucose elevation is a kind of mucilaginous SDF. The mechanism by which this suppression occurs may be largely attributable to the delayed absorption of glucose from the intestinal membrane in the upper digestive tract by viscous SDF.

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