scholarly journals T1 Mapping Quantifies Spinal Cord Compression in Patients With Various Degrees of Cervical Spinal Canal Stenosis

2020 ◽  
Vol 11 ◽  
Author(s):  
Ilko L. Maier ◽  
Sabine Hofer ◽  
Eva Eggert ◽  
Katharina Schregel ◽  
Marios-Nikos Psychogios ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Compression ◽  
Spinal Canal ◽  
T1 Mapping ◽  
Cord Compression ◽  
Spinal Canal Stenosis ◽  
Canal Stenosis ◽  
Cervical Spinal Canal

scholarly journals Quantification of spinal cord compression using T1 mapping in patients with cervical spinal canal stenosis – Preliminary experience

2019 ◽  
Vol 21 ◽  
pp. 101639 ◽  
Author(s):  
Ilko L. Maier ◽  
Sabine Hofer ◽  
Arun A. Joseph ◽  
K. Dietmar Merboldt ◽  
Eva Eggert ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Compression ◽  
Spinal Canal ◽  
T1 Mapping ◽  
Cord Compression ◽  
Spinal Canal Stenosis ◽  
Canal Stenosis ◽  
Cervical Spinal Canal

scholarly journals Clinical implications morphometric study of the cervical spine on MRI

2019 ◽  
Vol 10 (2) ◽  
Author(s):  
Swati S.More ◽  
Anita R. Gune ◽  
Jeetendra K. Patil
Keyword(s):  
Spinal Cord ◽  
Vertebral Body ◽  
Spinal Cord Compression ◽  
Spinal Canal ◽  
Cord Compression ◽  
Cervical Region ◽  
Canal Stenosis ◽  
Cervical Spinal Canal ◽  
Canal Diameter ◽  
Increased Risk

Degenerative changes, history of trauma or inflammation usually progressed to cervical spinal canal stenosis.  This condition leads to cervical spondylosis neuropraxia and cervical spondylotic myelopathy (CSM). SAC (space available for the cord) value is important to understand the symptoms of spinal cord compression in cervical canal stenosis. The aim of our study is to establish cervical spinal canal morphometry in Western Maharashtra population observed by MRI of cervical region.70 subjects aged between 18-70 years. The sagittal vertebral body diameter, the sagittal spinal canal diameter and the sagittal spinal-cord diameter were measured at the C3 - C7 level. The SAC was determined. For each variable a two-way ANOVA was performed, sagittal canal diameter, sagittal spinal cord diameter and SAC were significant with p-value P< 0.0001**. Mean vertebral body diameters observed were 1.49-1.51. Values of SAC observed were C3-1.5 cm, C4- 1.51cm, C5- 1.49cm, C6- 1.5cm, C7- 1.49cm. Average sagittal spinal canal diameter from C3-C7 was 14.1± 1.3 mm. The range of SAC was between 6.4-9.5mm, least at the C5 level. We conclude that subjects in our study do not have an increased risk of spinal cord compression.

scholarly journals Could spinal canal compression be a cause of polyneuropathy?

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Richard Bostelmann ◽  
Samis Zella ◽  
Hans Jakob Steiger ◽  
Athanasios K. Petridis
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Compression ◽  
Spinal Canal ◽  
Unknown Origin ◽  
Diabetic Polyneuropathy ◽  
Cord Compression ◽  
Spinal Canal Stenosis ◽  
Short Report ◽  
Canal Stenosis

Causality between spinal cord compression and polyneuropathy is difficult to define, especially under the circumstances that polyneuropathy can have many causes. Seven patients with spinal cord compression and electrophysiological signs of polyneuropathy were treated surgically on decompression of their spinal canal stenosis in the time from April 2010 to January 2013. Median follow up time was 9 months (2-23 months). Causes of polyneuropathy were: 1 patient with methotrexate-induced polyneuropathy, 1 endocrine-dysfunction-induced, 2 with diabetic- polyneuropathy, and 3 patients had unknown reasons. The localization of the spinal canal stenosis was also varying: 2 patients suffered of cervical spinal canal stenosis and 5 of lumbar. Decompressive surgery led to pain relieve in all patients initially. Surprisingly, also symptoms of polyneuropathy seemed to regress in all 7 patients for the first 5 months after surgery, and in 5 patients for the time of 9 months after surgery. There are two points we would like to emphasize in this short report. Since 5/7 patients with polyneuropathy and spinal canal stenosis improved clinically after surgery, surgery has a place in the treatment of such a combined pathology. Since it seems to be a possible causality between polyneuropathy of unknown origin and spinal cord stenosis, decompression of the spinal canal could also be a therapeutic step in a specific kind of polyneuropathy. Which patients could possibly have a spinal canal stenosis induced polyneuropathy remains a subject of further studies.

Cervical Spinal Cord Compression Attributable to a Calcified Intervertebral Disc in a Patient with X-linked Hypophosphatemic Rickets: Case Report and Review of the Literature

Neurosurgery ◽  
2002 ◽  
Vol 51 (1) ◽  
pp. 239-243 ◽  
Author(s):  
Martin Soehle ◽  
Adrian T.H. Casey
Keyword(s):  
Spinal Cord ◽  
Intervertebral Disc ◽  
Spinal Cord Compression ◽  
Spinal Canal ◽  
Facet Joint ◽  
Cord Compression ◽  
Spinal Canal Stenosis ◽  
Hypophosphatemic Rickets ◽  
Cervical Cord ◽  
Canal Stenosis

Abstract OBJECTIVE AND IMPORTANCE X-linked hypophosphatemic rickets is a common inherited phosphate-wasting disorder, but it is a rare cause of spinal cord compression. We present the first reported case of a calcified intervertebral disc causing spinal canal stenosis in X-linked hypophosphatemic rickets. CLINICAL PRESENTATION A 44-year-old woman presented with paresthesia of her left arm and a loss of grip in both hands. Magnetic resonance imaging revealed a calcified intervertebral disc, as well as a posterior osteophytic bar causing marked cervical cord compression at C6/C7. INTERVENTION An anterior cervical discectomy at C6/C7 and fusion with autologous bone graft were performed. The patient then exhibited significant improvement. CONCLUSION A review of the 16 published cases demonstrates that thickening of the vertebral laminae, facet joint hypertrophy, and ossification of the intervertebral discs, posterior longitudinal ligament, and/or ligamentum flavum contribute to spinal canal stenosis in X-linked hypophosphatemic rickets. Those changes are caused by the disease itself and are unlikely to be related to long-term vitamin D treatment. Eleven of 16 patients were reported to have experienced favorable outcomes after surgery.

scholarly journals Assessment of spinal cord motion as a new diagnostic MRI-parameter in cervical spinal canal stenosis: study protocol on a prospective longitudinal trial

2019 ◽  
Vol 14 (1) ◽  
Author(s):  
Katharina Wolf ◽  
Axel J. Krafft ◽  
Karl Egger ◽  
Jan-Helge Klingler ◽  
Ulrich Hubbe ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Canal ◽  
Diagnostic Marker ◽  
Clinical Course ◽  
Spinal Canal Stenosis ◽  
Diagnostic Process ◽  
Control Group ◽  
Canal Stenosis ◽  
Cervical Spinal Canal ◽  
Prospective Longitudinal

Abstract Background Increased spinal cord motion has been proven to be a relevant finding within spinal canal stenosis disclosed by phase-contrast MRI (PC-MRI). Adapted PC-MRI is a suitable and reliable method within the well deliberated setting. As the decision between conservative and operative treatment can be challenging in some cases, further diagnostic marker would facilitate the diagnostic process. We hypothesize that increased spinal cord motion will correlate to clinical course and functional impairment and will contribute as a new diagnostic marker. Methods A monocentric, prospective longitudinal observational trial on cervical spinal canal stenosis will be conducted at the University Medical Center Freiburg. Patients (n = 130) with relevant cervical spinal canal stenosis, being defined by at least contact to the spinal cord, will be included. Also, we will examine a control group of healthy volunteers (n = 20) as proof-of-principle. We will observe two openly assigned branches of participants undergoing conservative and surgical decompressive treatment (based on current German Guidelines) over a time course of 12 month, including a total of 4 visits. We will conduct a broad assessment of clinical parameters, standard scores and gradings, electrophysiological measurements, standard MRI, and adapted functional PC-MRI of spinal cord motion. Primary endpoint is the evaluation of an expected negative correlation of absolute spinal cord displacement to clinical impairment. Secondary endpoints are the evaluation of positive correlation of increased absolute spinal cord displacement to prolonged evoked potentials, prediction of clinical course by absolute spinal cord displacement, and demonstration of normalized spinal cord motion after decompressive surgery. Discussion With the use of adapted, non-invasive PC-MRI as a quantitative method for assessment of spinal cord motion, further objective diagnostic information can be gained, that might improve the therapeutic decision-making process. This study will offer the needed data in order to establish PC-MRI on spinal cord motion within the diagnostic work-up of patients suffering from spinal canal stenosis. Trial registration German Clinical Trials Register, ID: DRKS00012962, Register date 2018/01/17

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