scholarly journals Afterdischarges in Myasthenia Gravis

2021 ◽  
Vol 12 ◽  
Author(s):  
Li Yang ◽  
Shougang Guo ◽  
Xiuying Chen
Keyword(s):  
Tyrosine Kinase ◽  
Myasthenia Gravis ◽  
Clinical Features ◽  
Nerve Stimulation ◽  
Nerve Conduction ◽  
Motor Nerve ◽  
Repetitive Nerve Stimulation ◽  
Motor Nerve Conduction ◽  
M Wave ◽  
F Wave

Introduction: This study aimed to analyze the clinical features of myasthenia gravis (MG) in combination with the afterdischarges and compare the characteristics of afterdischarges in MG with different serum antibodies.Methods: Ninety-two patients with MG were analyzed retrospectively. The afterdischarges were investigated using motor nerve conduction examination, F-wave examination, and repetitive nerve stimulation (RNS).Results: Afterdischarges were observed after the M wave in 14 of 92 patients. Three of these 14 patients tested positive for the muscle-specific tyrosine kinase antibody (MuSK-Ab), and 11 patients tested positive for the acetylcholine receptor antibody (AchR-Ab). The characteristics of the afterdischarges on RNS differed distinctly between the two antibody groups. The afterdischarges occurred on the first stimulation, but decreased on the second and subsequent stimulations in patients with MuSK-MG, while the afterdischarges continued to occur on each stimulation in patients with AchR-MG.Discussion: The characteristics of the afterdischarges on RNS enabled easy identification of their synaptic or neurogenic nature.

MOTOR NERVE CONDUCTION AND REPETITIVE NERVE STIMULATION IN CAPTIVE RING-TAILED COATI (NASUA NASUA)

2012 ◽  
Vol 43 (3) ◽  
pp. 443-449
Author(s):  
Ana Carolina Mortari ◽  
Sheila Canevese Rahal ◽  
Luiz Antonio de Lima Resende ◽  
Carlos Roberto Teixeira ◽  
Rodrigo Hidalgo Friciello Teixeira ◽  
...  
Keyword(s):  
Nerve Stimulation ◽  
Nerve Conduction ◽  
Motor Nerve ◽  
Repetitive Nerve Stimulation ◽  
Motor Nerve Conduction ◽  
Nasua Nasua

scholarly journals Nerve Conduction Studies in Patients with Lumbosacral Radiculopathy Caused by Lumbar Intervertebral Disc Herniation

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Safa Yousif ◽  
Ammar Ahmed ◽  
Ahmed Abdelhai ◽  
Afraa Musa
Keyword(s):  
Nerve Conduction Study ◽  
Nerve Conduction ◽  
Tibial Nerve ◽  
Motor Nerve ◽  
H Reflex ◽  
Nerve Conduction Studies ◽  
Control Group ◽  
Motor Nerve Conduction ◽  
Lumbosacral Radiculopathy ◽  
F Wave

Background. Nerve conduction studies (NCS) are electrodiagnostic tests used to evaluate peripheral nerves functions and aid in the assessment of patients with neuromuscular complaints. There is contrasting evidence concerning the use of NCS in the assessment of patients with lumbosacral radiculopathy. Objectives. This study was conducted to evaluate nerve conduction studies abnormalities in patients with lumbosacral radiculopathy and to find out their relation to abnormal physical examination findings. Materials and Methods. Twenty-seven patients with lumbosacral radiculopathy caused by L4/5 or L5/S1 intervertebral disc prolapse confirmed by magnetic resonance imaging (MRI) were recruited in the study. Twenty-five healthy subjects matched in age and sex served as control. Motor nerve conduction study bilaterally for both common peroneal and tibial nerves, F-wave for both nerves, and H-reflex had been conducted. Results. No significant difference was found in the motor nerve conduction study parameters (latency, amplitude, and conduction velocity) between the patients group and the control group. There was significant prolongation in H-reflex latency of both symptomatic and asymptomatic side in the patients group compared to the control group ( P < 0.05 ). Also, F-wave latencies (F minimum, F maximum, and F mean) of the tibial nerve were significantly prolonged ( P < 0.05 ) compared to control. Conclusion. Prolonged H-reflex latency was the commonest encountered abnormality in our study followed by F-wave latencies of the tibial nerve.

scholarly journals Motor nerve conduction study parameters in healthy individuals: effect of limb dominance

2019 ◽  
Vol 7 (4) ◽  
pp. 1330
Author(s):  
Binnam Shakya ◽  
Dilip Thakur ◽  
Bishnu H. Paudel ◽  
Rita Khadka ◽  
Suman Pokhrel
Keyword(s):  
Ulnar Nerve ◽  
Nerve Conduction Study ◽  
Nerve Conduction ◽  
Motor Nerve ◽  
Healthy Individuals ◽  
Motor Nerve Conduction ◽  
Left Handed ◽  
F Wave ◽  
Wave Minimum ◽  
Limb Dominance

Background: Nerve conduction study (NCS) is useful for evaluation of nerve, muscle, and/or neuromuscular function. Neurophysiologist interprets NCS with consideration of various anthropometric and technical parameters viz. age, gender, height, temperature etc. apart from the underlying pathology. Fewer studies have reported the effect of limb dominance on NCS. Moreover, the findings are controversial. Therefore, author aimed to investigate the effect of limb dominance on motor nerve conduction study parameters.Methods: This cross-sectional comparative study included sixty healthy individuals (44 right and 16 left handed) of either sex with age 18 to 30 years. The NCS parameters of median and ulnar nerves were assessed by stimulating it and recording from the muscle and skin overlying the nerve respectively using Digital Nihon Kohden machine. The obtained data were analyzed using independent sample t-test.Results: Right ulnar nerve onset latency was significantly longer in left-handed individuals (1.85±0.508 ms vs 1.62±0.195 ms, p=0.012). The left ulnar nerve F wave minimum latency (25.88±0.74 ms vs 24.46±2.64 ms, p=0.002) was significantly longer in left-handed individuals. Likewise, right ulnar nerve distal latency (2.45±0.76 ms vs 2.14±0.39 ms, p=0.044), and right ulnar nerve F wave minimum (25.9±1.21 ms vs 24.85 ms±1.74, p=0.030) were significantly high in left-handed individuals.Conclusions: NCS parameters in terms of latencies were longer in left-handed individuals. Therefore, limb dominance seems to be an important factor one should pay attention during bilateral comparison of obtained data in neurophysiological reporting of referred cases.

scholarly journals The Myotonic Plot Thickens: Electrical Myotonia in Antimuscle-Specific Kinase Myasthenia Gravis

2015 ◽  
Vol 2015 ◽  
pp. 1-4
Author(s):  
Marcus Magnussen ◽  
Ioannis Karakis ◽  
Taylor B. Harrison
Keyword(s):  
Differential Diagnosis ◽  
Respiratory Failure ◽  
Tyrosine Kinase ◽  
Myasthenia Gravis ◽  
Nerve Stimulation ◽  
Inflammatory Myopathies ◽  
Proximal Muscle Weakness ◽  
Proximal Muscle ◽  
Repetitive Nerve Stimulation ◽  
Early Recruitment

Electrical myotonia is known to occur in a number of inherited and acquired disorders including myotonic dystrophies, channelopathies, and metabolic, toxic, and inflammatory myopathies. Yet, electrical myotonia in myasthenia gravis associated with antibodies against muscle-specific tyrosine kinase (MuSK) has not been previously reported. We describe two such patients, both of whom had a typical presentation of proximal muscle weakness with respiratory failure in the context of a significant electrodecrement in repetitive nerve stimulation. In both cases, concentric needle examination revealed electrical myotonia combined with myopathic motor unit morphology and early recruitment. These findings suggest that MuSK myasthenia should be included within the differential diagnosis of disorders with electrical myotonia.

Ratio of Motor Nerve Conduction Velocity to F-Wave Conduction Velocity in Diabetic Neuropathy

Diabetes Care ◽  
1998 ◽  
Vol 21 (4) ◽  
pp. 615-618 ◽  
Author(s):  
K. Ohgaki ◽  
K. Nakano ◽  
H. Shigeta ◽  
Y. Kitagawa ◽  
N. Nakamura ◽  
...  
Keyword(s):  
Diabetic Neuropathy ◽  
Conduction Velocity ◽  
Nerve Conduction ◽  
Nerve Conduction Velocity ◽  
Motor Nerve ◽  
Motor Nerve Conduction Velocity ◽  
Motor Nerve Conduction ◽  
F Wave
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