scholarly journals Speech sound discrimination training improves auditory cortex responses in a rat model of autism

Author(s):  
Crystal T. Engineer ◽  
Tracy M. Centanni ◽  
Kwok W. Im ◽  
Michael P. Kilgard
2019 ◽  
Author(s):  
Stephen M. Town ◽  
Katherine C. Wood ◽  
Jennifer K. Bizley

AbstractThe ability to recognize sounds in noise is a key part of hearing, and the mechanisms by which the brain identifies sounds in noise are of considerable interest to scientists, clinicians and engineers. Yet we know little about the necessity of regions such as auditory cortex for hearing in noise, or how cortical processing of sounds is adversely affected by noise. Here we used reversible cortical inactivation and extracellular electrophysiology in ferrets performing a vowel discrimination task to identify and understand the causal contribution of auditory cortex to hearing in noise. Cortical inactivation by cooling impaired task performance in noisy but not clean conditions, while responses of auditory cortical neurons were less informative about vowel identity in noise. Simulations mimicking cortical inactivation indicated that effects of inactivation were related to the loss of information about sounds represented across neural populations. The addition of noise to target sounds drove spiking activity in auditory cortex and recruitment of additional neural populations that were linked to degraded behavioral performance. To suppress noise-related activity, we used continuous exposure to background noise to adapt the auditory system and recover behavioral performance in both ferrets and humans. Inactivation by cooling revealed that the benefits of continuous exposure were not cortically dependent. Together our results highlight the importance of auditory cortex in sound discrimination in noise and the underlying mechanisms through which noise-related activity and adaptation shape hearing.


1970 ◽  
Vol 13 (1) ◽  
pp. 178-183
Author(s):  
Stuart I. Ritterman

This study examined the use of vicarious experience in the establishment of the discriminative responses comprising a repertoire of phonetic distinctions. A modification of a technique developed by Warden (Warden and Jackson, 1935) for the study of observer and model group learning was employed in the speech-sound discrimination training of 41 second grade children. Retroactive facilitation effects were observed in the observation group. In addition, no differences in group performance were obtained between observer and model groups in a relearning situation.


1974 ◽  
Vol 17 (3) ◽  
pp. 417-425
Author(s):  
Stuart I. Ritterman ◽  
Nancy C. Freeman

Thirty-two college students were required to learn the relevant dimension in each of two randomized lists of auditorily presented stimuli. The stimuli consisted of seven pairs of CV nonsense syllables differing by two relevant dimension units and from zero to seven irrelevant dimension units. Stimulus dimensions were determined according to Saporta’s units of difference. No significant differences in performance as a function of number of the irrelevant dimensions nor characteristics of the relevant dimension were observed.


1969 ◽  
Vol 35 (9) ◽  
pp. 745-747 ◽  
Author(s):  
Ronald Goldman ◽  
Macalyne Fristoe

Author(s):  
Arnold Abramovitz

It is certain that many children whose auditory perception is queried by audiologists, speech therapists, educationists and psychologists elude the diagnostic screens presently available in each of these disciplines. The need for a qualitative and quantitative psychological assessment of the child's auditory abilities and disabilities led to the development of a test which was intended to evaluate the following functions:(a) Recognition of environmental sounds, (b) Auditory figure-ground discrimination, (c) Speech-sound discrimination (phonemic and intonational) and (d) Tonal pattern discrimination (pitch, loudness, duration and interval). It was not intended to investigate threshold phenomena as such but rather to supplement and complement pure-tone and speech audiometry. The test was applied to 205 children, aged five to ten years, drawn from a normal school population, and 232 children with difficulties and handicaps varying both in degree and kind. Only the first two sub-tests were found to be clinically and experimentally viable, and data for the curtailed test are presented. The following results are noteworthy: (1) The test measures functions which are positively related to both age and intelligence. (2) Brain-injured, retarded and emotionally disturbed children generally test low on auditory figure-ground discrimination; this vulnerability is most likely due to perseveration. (3) Previously unsuspected peripheral hearing losses may sometimes be detected by the use of the test. On the other hand, some children said to have high degrees of hearing loss test at or above their age-level. (4) Many deaf and hard-of-hearing children test higher without their hearing-aids; this is probably due to amplification being achieved at the cost of distortion. (5) Children of average intelligence with reading and/or spelling difficulties often test low on auditory figure-ground discrimination. (6) Blind children who have received auditory training are equal to sighted children in recognition of environmental sounds, but superior in auditory figure-ground discrimination. This does not, however, necessarily signify superior auditory perception as such on the part of the blind. In general it is concluded that the development of tests of auditory perception could add significantly to the psycho-educational assessment of both "normal" and handicapped children.


NeuroImage ◽  
2018 ◽  
Vol 178 ◽  
pp. 735-743 ◽  
Author(s):  
Silvia P. Gennari ◽  
Rebecca E. Millman ◽  
Mark Hymers ◽  
Sven L. Mattys

2020 ◽  
pp. 541-558
Author(s):  
Dennis L. Molfese ◽  
Victoria J. Molfese ◽  
Alexandra Fonaryova Key ◽  
Spencer D. Kelly

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