scholarly journals Cerebral Regional Homogeneity Alternation of Pregnant Women With Antenatal Depression During the Pandemic

2021 ◽  
Vol 12 ◽  
Author(s):  
Bochao Cheng ◽  
Yajing Meng ◽  
Yushan Zhou ◽  
Jinrong Li ◽  
Jianguang Zeng ◽  
...  

Purpose: The COVID-19 epidemic has been a threat to the health of people all over the world. Various precautions during COVID-19 in China have kept a large number of people in isolation, and this has inconvenienced and placed enormous stress on pregnant women. Pregnant women are more likely to suffer from antenatal depression (ANDP) with social isolation or low social support. This research aims to investigate the neurobiological mechanisms underlying ANDP, which impedes early detection and intervention in this disorder.Methods: A total of 43 singleton pregnant women who experienced isolation were recruited, including 21 treatment-naïve ANDP patients and 22 healthy pregnant women (HPW). To explore the intrinsic cerebral activity alternations in ANDP using resting-state functional MRI (rsfMRI), we assessed the local regional homogeneity (ReHo) differences in two groups using the voxel-based whole-brain analysis. The correlation between the regional functional abnormalities and clinical variables in ANDP patients was also examined.Results: Compared with HPW, ANDP patients showed decreased ReHo in the left dorsolateral prefrontal cortex, right insular and the cluster coving the right ventral temporal cortex (VTC), amygdala (AMG), and hippocampus (HIP). The Edinburgh Postnatal Depression Scale (EPDS) scores of ANDP patients negatively correlated with the ReHo in the right VTC, AMG, and HIP.Conclusion: Elucidating the neurobiological features of ANDP patients during COVID-19 is crucial for evolving adequate methods for early diagnosis, precaution, and intervention in a future epidemic.

2018 ◽  
Vol 53 (5) ◽  
pp. 424-432 ◽  
Author(s):  
Fiona Judd ◽  
Stephanie Lorimer ◽  
Richard H Thomson ◽  
Angela Hay

Objective: The aim of the study was to explore the range of psychiatric diagnoses seen in pregnant women who score above the ‘cut-off’ on the Edinburgh Postnatal Depression Scale when this is used as a routine screening instrument in the antenatal period. Method: Subjects were all pregnant women referred to and seen by the Perinatal Consultation-Liaison Psychiatry Team of a tertiary public hospital over a 14-month period. Edinburgh Postnatal Depression Scale score at maternity ‘booking-in’ visit, demographic and clinical data were recorded and diagnoses were made according to Diagnostic and Statistical Manual of Mental Disorders (5th ed.) criteria following clinical interview(s) and review of documented past history. Data were analysed using descriptive statistics. Results: A total of 200 patients who had completed the Edinburgh Postnatal Depression Scale were seen for assessment; 86 (43%) scored ⩾13 on Edinburgh Postnatal Depression Scale. Of those scoring 13 or more on Edinburgh Postnatal Depression Scale, 22 (25.6%) had a depressive disorder. In total, 12 patients (14%) had an anxiety disorder, 14 (16.3%) had borderline personality disorder and 13 (15.1%) had a substance use disorder. An additional 23 women (26.7%) had two or more borderline personality traits. Conclusion: Psychiatric assessment of women who scored 13 or more on the Edinburgh Postnatal Depression Scale at routine antenatal screening identified a significant number with borderline personality disorder or borderline personality traits rather than depressive or anxiety disorders. Clinical Practice Guidelines note the importance of further assessment for all women who score 13 or more on the Edinburgh Postnatal Depression Scale. The findings here suggest that this assessment should be made by a clinician able to identify personality pathology and organise appropriate and timely interventions.


2014 ◽  
Vol 75 (04) ◽  
pp. 393-398 ◽  
Author(s):  
Linda B. Lydsdottir ◽  
Louise M. Howard ◽  
Halldora Olafsdottir ◽  
Marga Thome ◽  
Petur Tyrfingsson ◽  
...  

2019 ◽  
Vol 31 (2) ◽  
pp. 113-120 ◽  
Author(s):  
Raheema Abdul Raheem ◽  
Hui Jun Chih ◽  
Colin William Binns

Objectives: To assess associations between maternal depression and breastfeeding practices in mothers in the Maldives. Design: A prospective cohort study. The validated questionnaires contained information on demographics, breastfeeding initiation, breastfeeding duration, and the Edinburgh Postnatal Depression Scale. Logistic regression analyses were used to assess association between Edinburgh Postnatal Depression Scale score and breastfeeding practices while adjusting for lifestyle determinants. Cox regression was done to measure the association between maternal depression and breastfeeding duration. Settings: Antenatal clinic at Indira Gandhi Memorial and ADK Hospitals in Male’, Maldives. Subjects: A total of 458 mothers from the antennal clinics were interviewed at 36 weeks of gestation and again at 1, 3, and 6 months after birth. Results: Antenatal depression at 36 weeks of gestation was associated with late initiation of breastfeeding (adjusted odds ratio = 3.0, 95% confidence interval = 1.3-6.8). Postnatal depression was associated with shorter duration of exclusive, full, and any breastfeeding ( P < .001). Conclusion. Depression is negatively associated with breastfeeding practices. There is a need to manage antenatal postnatal depression in mothers in order to encourage them to initiate breastfeeding earlier and to breastfeed for longer.


2019 ◽  
Author(s):  
Meili Xiao ◽  
Bing Fu ◽  
Chunmei Mi ◽  
Chen Pan ◽  
Shujuan Zhu ◽  
...  

Abstract Background: Few studies investigated the association between the pregnancy intention to have a second child and antenatal depressive symptoms.The aim of this study was to explore the association between the pregnancy intention to have a second child by pregnant women’s own desires, pregnant women’s husband own desires, parents who want to grandchild desires, couple’s concordance desires and antenatal depressive symptoms. Methods: A total of 306 participants who completed questionnaire were included in our analysis. Antenatal depressive symptom was assessed using the Chinese version of Edinburgh Postnatal Depression Scale. Logistic regression models were used to estimate the association between the pregnancy intention to have a second child by pregnant women’s own desires, pregnant women’s husband own desires, parents who want to grandchild desires and antenatal depressive symptoms. Results: the prevalence of antenatal depressive symptoms was 36.3% among the second child pregnant women. Of the 306 participants, the proportion of the pregnancy intention to have a second child by pregnant women’s own desires, pregnant women’s husband desires, parents who want to grandchild desires and couple’s concordance desires was 8.5%, 8.5%, 10.8% and 72.2% respectively. Compared with the pregnancy intention by couple’s concordance desires, pregnant women’s own desires to have a second child had higher risk of antenatal depressive symptoms after adjustment for potential confounders (OR=4.560, 95%CI: 1.603,12.973). No association was found between the pregnancy intention to have a second child by pregnant women’s husband own desires, parents who want to grandchild desires and antenatal depressive symptoms after adjustment for confounders (OR=1.996, 95%CI:0.781,5.105; OR=0.744, 95%CI: 0.306,1.811, respectively). Conclusion: These findings suggest the pregnancy intention to have a second child by pregnant women own’s desires may be a risk factors for antenatal depressive symptoms among two-child pregnant women. A qualitative study should be carried out to investigate the real reason for the intention by pregnant women’s own desires and antenatal depressive symptoms in the future, because of this study was a quantitative study. Key words: pregnancy intention; antenatal depressive symptoms; second child


Author(s):  
Jayashree Kannappan ◽  
Abhilash Kannappan ◽  
V. S. Prema Subathiraa ◽  
Shanthi Dinakaran ◽  
P. S. Jikki Kalaselvi

Background: Women are twice as likely as males to suffer from mood disorders, which tend to cluster around the childbearing years. Depression negatively influences maternal and neonatal outcomes. Objective: The objective of the study is to estimate the prevalence of depression in pregnant women aged 18 – 35 yrs and to identify predictors accounting for variability across estimates during pandemic. Methodology: This is a cross sectional study, conducted among 74 pregnant women coming for antenatal checkups in the Sriperumbudur, Chennai. Using height and weight values obtained from the sample, Body Mass Index (weight in kg/height in metre squares) was calculated. Hamilton – Depression Scale (HAM-d) was applied after initial psychiatry work up to all women who were selected for the interview. Mean of parameters were assessed and correlation value were calculated by Fisher’s exact test. The statistically significant P value was less than 0.05. Results: The sociodemographic variables have been found as significant contributors in explaining the variability of the prevalence rates of antenatal depression. It showed positive correlation between economic status and depression (p<0.05) and a negative correlation between obesity and depression (p>0.05). According to the findings, fewer than 1/3rd of pregnant women experience depression as a result of life circumstances such as economic crises in order to support their families. These were identified as significant associate variables (P>0.05). And also, this study identified insufficient socioeconomic assistance were more likely to experience multiple psychological discomfort [atleast 1] than women who got appropriate economic support. (r = -0.118, P < 0.001) Conclusion: In rural Tamilnadu, the prevalence of antenatal depression among women is significant. Antenatal Depression is caused by a number of circumstances, including physical, obstetric, economic, and family-related issues. To treat these antenatal depression risk factors, comprehensive therapies are required.


2000 ◽  
Vol 5 (1) ◽  
pp. 52-61 ◽  
Author(s):  
Herbert F. Mackinger ◽  
Gertrude G. Loschin ◽  
Max M. Leibetseder

Specificity and categoric descriptions of autobiographical memories (AM) are reported to be psychological trait markers for vulnerability for depression. Thus, they should permit the prediction of future affective changes. Fifty pregnant women were tested for their recall of AM as well as twice—during pregnancy and 3 months after delivery—with the Edinburgh Postnatal Depression Scale (EPDS; Cox, Holden & Sagovsky, 1987 ). The main scope of the study was the evaluation of the potential of AM in predicting affective changes in a nonclinical sample of women following childbirth. Using a hierarchical multiple regression analysis, categoric descriptions in response to negative cue words allowed a significant prediction of affective changes.


BMJ Open ◽  
2019 ◽  
Vol 9 (9) ◽  
pp. e030365 ◽  
Author(s):  
Sarah Naja ◽  
Noora Al-Kubaisi ◽  
Mohamad Chehab ◽  
Ayman Al-Dahshan ◽  
Nada Abuhashem ◽  
...  

ObjectivesThe current study aimed to validate and determine the psychometric properties of the Arabic versions of the Beck Depression Inventory-II (BDI-II) and the Edinburgh Postnatal Depression Scale (EPDS) in Qatar.DesignA cross-sectional study design was employed.SettingAntenatal care (ANC) clinics at nine primary healthcare centres.ParticipantsPregnant women (n=128) aged 15–46 years in different trimesters of pregnancy, attending the ANC clinics as well as capable of reading and writing in the Arabic language.ResultsA total of 128 participants were enrolled. On conducting the receiver operating characteristic (ROC) analysis, the EPDS showed a larger area under the curve at 0.951 than the BDI-II tool (0.912). Using Youden’s index, a score>13 on the EPDS (87% sensitivity, 90% specificity) and>19 on the BDI-II (96% sensitivity, 73% specificity) allowed for the greatest division between depressed and non-depressed participants.ConclusionTo address the under-recognition of antenatal depression, physicians at primary healthcare centres in Qatar should be encouraged to utilise the EPDS to screen pregnant women seeking ANC services.


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