scholarly journals Association Between Changes in Muscle Strength and Risk of Depressive Symptoms Among Chinese Female College Students: A Prospective Cohort Study

2021 ◽  
Vol 9 ◽  
Author(s):  
Jianhua Cao ◽  
Fang Zhao ◽  
Zhongyu Ren

Muscle strength can be a predictor of depressive symptoms among the elderly. We conducted a prospective study aiming to examine the association between change of handgrip strength and the incidence risk of depressive symptoms among Chinese female college students. Handgrip strength was used as a representative indicator of skeletal muscle strength, and a handheld digital smedley dynamometer was applied to measure handgrip strength. We also used the 20-item Zung self-rating depression scale to evaluate depressive status, and a score of ≥50 indicated moderate-to-severe depressive symptoms. During a 1-year follow-up period, the incidence of depressive symptoms is 10.7%. Multivariate logistic regressions analysis revealed that the multivariable-adjusted ORs (95% CI) of depressive symptoms for the categories of handgrip strength change was 1.00 (reference) for group 1, 0.57 (0.28, 1.19) for group 2, 0.41 (0.19, 0.89) for group 3 and 0.33 (0.11, 0.99) for group 4 (p = 0.018). This study indicated that change of handgrip strength level over one-year period is negatively associated with risk of depressive symptoms among Chinese female college students.

2008 ◽  
Vol 24 (3) ◽  
pp. 464-481 ◽  
Author(s):  
Bizu Gelaye ◽  
Dodie Arnold ◽  
Michelle A. Williams ◽  
Miruts Goshu ◽  
Yemane Berhane

2020 ◽  
Author(s):  
Liya Guo ◽  
Jianhua Cao ◽  
Yingke Li ◽  
Guang Yang ◽  
peng cheng ◽  
...  

Abstract Increased physical activity level is related to lower risk of depressive symptoms, and an inverse association between muscular strength and risk of depressive symptoms among the elderly population. However, the association among younger adults is unclear. The aim of this study was to examine the association between muscle strength, using handgrip strength as a representative of skeletal muscle strength, and the risk of depressive symptoms among Chinese female college freshman. A cross-sectional study was conducted among 867 participants aged between 16-23 years. Handgrip strength was measured with a handheld digital Smedley dynamometer, and depressive symptoms were evaluated using the 20-item Zung self-rating depression scale (SDS) with 3 cut-off points to indicate elevated depressive symptoms. We found that 10.7% of participants (17.2% or 29.2%) were classified as having moderate to severe depressive symptoms using 50 as the cut-off point. After adjusting for these potential confounders, the adjusted odds ratios for moderate-to-severe depressive symptoms across tertile of relative handgrip strength were 1.00 (reference) for tertile 1, 0.61 (95% CI: 0.35, 1.04) for tertile 2, and 0.53 (95% CI: 0.39, 0.94) for tertile 3 (P for trend: 0.024). The significant associations remained when other cut-off points (SDS 48 or 45) were used. Interactions between the handgrip strength and potential confounders for depressive symptoms in the final models were insignificant. This study showed that handgrip strength is inversely and independently related to the risk of depressive symptoms among Chinese female college freshman. These results can help with the development of an effective intervention strategy against depression. For future research, it is important to explore the causality of the effects of handgrip strength on the depressive symptoms by intervention study.


2019 ◽  
Author(s):  
Zhongyu Ren ◽  
Liya Guo ◽  
Jianhua Cao ◽  
Yingke Li ◽  
Guang Yang ◽  
...  

Abstract Increased physical activity level is related to lower risk of depressive symptoms, and an inverse association between muscular strength and risk of depressive symptoms among the elderly population. However, the association among younger adults is unclear. The aim of this study was to examine the association between muscle strength, using handgrip strength as a representative of skeletal muscle strength, and the risk of depressive symptoms among Chinese female college freshman. A cross-sectional study was conducted among 867 participants aged between 16-23 years. Handgrip strength was measured with a handheld digital Smedley dynamometer, and depressive symptoms were evaluated using the 20-item Zung self-rating depression scale (SDS) with 3 cut-off points to indicate elevated depressive symptoms. We found that 10.7% of participants (17.2% or 29.2%) were classified as having moderate to severe depressive symptoms using 50 as the cut-off point. After adjusting for these potential confounders, the adjusted odds ratios for moderate-to-severe depressive symptoms across tertile of relative handgrip strength were 1.00 (reference) for tertile 1, 0.61 (95% CI: 0.35, 1.04) for tertile 2, and 0.53 (95% CI: 0.39, 0.94) for tertile 3 (P for trend: 0.024). The significant associations remained when other cut-off points (SDS 48 or 45) were used. Interactions between the handgrip strength and potential confounders for depressive symptoms in the final models were insignificant. This study showed that handgrip strength is inversely and independently related to the risk of depressive symptoms among Chinese female college freshman. These results can help with the development of an effective intervention strategy against depression. For future research, it is important to explore the causality of the effects of handgrip strength on the depressive symptoms by intervention study.


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