scholarly journals Advances in Magnetic Noble Metal/Iron-Based Oxide Hybrid Nanoparticles as Biomedical Devices

2019 ◽  
Vol 6 (3) ◽  
pp. 75 ◽  
Author(s):  
Laura M. Sanchez ◽  
Vera A. Alvarez

The study of the noble metal magnetic hybrid nanoparticles is a really promising topic from both the scientific and the technological points of views, with applications in several fields. Iron oxide materials which are hybridized with noble metal nanoparticles (NPs) have attracted increasing interest among researchers because of their cooperative effects on combined magnetic, electronic, photonic, and catalytic activities. This review article contains a summary of magnetic noble metal/iron oxide nanoparticle systems potentially useful in practical biomedical applications. Among the applications, engineered devices for both medical diagnosis and treatments were considered. The preparation to produce different structures, as blends or core-shell structures, of several nanometric systems was also considered. Several characterization techniques available to describe the structure, morphology and different kinds of properties of hybrid nanoparticles are also included in this review.

2021 ◽  
Vol 64 (2) ◽  
pp. 202-210
Author(s):  
Muhammad Isa Khan ◽  
Aliza Zahoor ◽  
Tahir Iqbal ◽  
Abdul Majid ◽  
Mohsin Ijaz

  Recently, different researchers find nanoparticles as an auspicious alternative to antibacterial agents due to their antibacterial behaviour. This antibacterial behaviour contributes in many biomedical applications including; tissue engineering, drug and gene delivery and, imaging. Furthermore, iron oxide nanoparticle gains much importance due to their magnetic characteristics and wide range of application. Iron oxide nanoparticle (IONPs) have exhibits great potential against bacteria. During the past decade, various routes were developed to synthesize iron oxide nanoparticle with suitable size and composition. This article reviews the recent iron oxide nanoparticle obtained by green synthesis with a focus on their response to antibacterial activities. The iron nanoparticles synthesized by green synthesis method has accumulated a vital attention over the last couple of years due to their unique characteristic as it makes sure environmental friendly, nontoxic and safe reagents.


2009 ◽  
Vol 16 (10) ◽  
pp. 1278-1294 ◽  
Author(s):  
J. Xie ◽  
J. Huang ◽  
X. Li ◽  
S. Sun ◽  
X. Chen

Drug Delivery ◽  
2017 ◽  
Vol 24 (1) ◽  
pp. 1317-1324 ◽  
Author(s):  
Daniel J. Denmark ◽  
Robert H. Hyde ◽  
Charlotte Gladney ◽  
Manh-Huong Phan ◽  
Kirpal S. Bisht ◽  
...  

Metals ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 383
Author(s):  
C. Fernández-Ponce ◽  
J. M. Mánuel ◽  
R. Fernández-Cisnal ◽  
E. Félix ◽  
J. Beato-López ◽  
...  

An optimal design of nanoparticles suitable for biomedical applications requires proper functionalization, a key step in the synthesis of such nanoparticles, not only for subsequent crosslinking to biological targets and to avoid cytotoxicity, but also to endow these materials with colloidal stability. In this sense, a reliable characterization of the effectiveness of the functionalization process would, therefore, be crucial for subsequent bioconjugations. In this work, we have analyzed glutathione as a means to functionalize four of the most widely used nanoparticles in biomedicine, one of which is a hybrid gold-magnetic-iron-oxide nanoparticle synthetized by a simple and novel method that we propose in this article. We have analyzed the colloidal characteristics that the glutathione capping provides to the different nanoparticles and, using information on the Z-potential, we have deduced the chemical group used by glutathione to link to the nanoparticle core. We have used electron microscopy for further structural and chemical characterization of the nanoparticles. Finally, we have evaluated nanoparticle cytotoxicity, studying cell viability after incubation with different concentrations of nanoparticles, showing their suitability for biomedical applications.


2021 ◽  
Author(s):  
Stephan Müssig ◽  
Björn Kuttich ◽  
Florian Fidler ◽  
Daniel Haddad ◽  
Susanne Wintzheimer ◽  
...  

The controlled agglomeration of superparamagnetic iron oxide nanoparticles (SPIONs) was used to rapidly switch their magnetic properties. Small-angle X-ray scattering (SAXS) and dynamic light scattering showed that tailored iron oxide...


2021 ◽  
Vol 13 (7) ◽  
pp. 7924-7944
Author(s):  
Yadileiny Portilla ◽  
Sara Mellid ◽  
Alberto Paradela ◽  
Antonio Ramos-Fernández ◽  
Neus Daviu ◽  
...  

Nanoscale ◽  
2019 ◽  
Vol 11 (27) ◽  
pp. 12905-12914 ◽  
Author(s):  
Manman Xie ◽  
Shijia Liu ◽  
Christopher J. Butch ◽  
Shaowei Liu ◽  
Ziyang Wang ◽  
...  

Superparamagnetic iron oxide nanoparticles (SPIONs) have a history of clinical use as contrast agents in T2 weighted MRI, though relatively low T2 relaxivity has caused them to fall out of favor as new faster MRI techniques have gained prominence.


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