scholarly journals Topological Characteristics Associated with Intraoperative Stimulation Related Epilepsy of Glioma Patients: A DTI Network Study

2021 ◽  
Vol 12 (1) ◽  
pp. 60
Author(s):  
Jianing Yang ◽  
Chunyao Zhou ◽  
Yuchao Liang ◽  
Yinyan Wang ◽  
Lei Wang
Keyword(s):  
Theoretical Analysis ◽  
Path Length ◽  
Marked Decrease ◽  
Lower Efficiency ◽  
Graph Theoretical Analysis ◽  
Presurgical Assessment ◽  
Topological Characteristics ◽  
Intraoperative Electrical Stimulation ◽  
Healthy Participants

Background: Awake craniotomy with intraoperative stimulation has been utilized in glioma surgical resection to preserve the quality of life. Epilepsy may occur in 5–20% of cases, leading to severe consequences. This study aimed to discuss the mechanism of intraoperative stimulation-related epilepsy (ISE) using DTI-based graph theoretical analysis. Methods: Twenty patients with motor-area glioma were enrolled and divided into two groups (Ep and nEp) according to the presence of ISE. Additionally, a group of 10 healthy participants matched by age, sex, and years of education was also included. All participants underwent T1, T2, and DTI examinations. Graph theoretical analysis was applied to reveal the topological characteristics of white matter networks. Results: Three connections were found to be significantly lower in at least one weighting in the Ep group. These connections were between A1/2/3truL and A4ulL, A1/2/3truR and A4tR, and A6mL and A6mR. Global efficiency was significantly decreased, while the shortest path length increased in the Ep group in at least one weighting. Ten nodes exhibited significant differences in nodal efficiency and degree centrality analyses. The nodes A6mL and A6mR showed a marked decrease in total four weightings in the Ep group. Conclusions: The hub nodes A6mL and A6mR are disconnected in patients with ISE, causing subsequent lower efficiency of global and regional networks. These findings provide a basis for presurgical assessment of ISE, for which caution should be taken when it involves hub nodes during intraoperative electrical stimulation.

scholarly journals Topological Characteristics Associated with Intraoperative Stimulation Related Epilepsy of Glioma Patients: A DTI Network Study

2021 ◽  
Author(s):  
Jianing Yang ◽  
Chunyao Zhou ◽  
Yuchao Liang ◽  
Yinyan Wang ◽  
Lei Wang
Keyword(s):  
Theoretical Analysis ◽  
Life Quality ◽  
Lower Efficiency ◽  
Graph Theoretical Analysis ◽  
Gender And Education ◽  
Significant Difference ◽  
Presurgical Assessment ◽  
Topological Characteristics ◽  
Intraoperative Electrical Stimulation ◽  
Centrality Analysis

Abstract Purpose Awake craniotomy with intraoperative stimulation has been utilized in glioma surgical resection to preserve life quality. While 5-20% of cases may occur epilepsy during the procedure which leads to severe consequences. The study aimed to discussing the mechanism of intraoperative stimulation-related epilepsy (ISE) with DTI based graph theoretical analysis.Methods 20 patients with motor-area glioma were enrolled and divided into 2 groups (Ep and nEp) according to whether there was ISE. Additionally, a group of 10 healthy participants matched by age, gender and education year were also involved. All participants underwent T1, T2 and DTI. Graph theoretical analysis was applied to reveal topological characteristics of the white matter networks. Results Three connections were found to be significantly lower in at least one weighting in Ep group. They are the connection between A1/2/3truL and A4ulL, A1/2/3truR and A4tR, and A6mL and A6mR. Global efficiency was found to be significantly decreased while the shortest path length increased in Ep group in at least one weighting. Ten nodes exhibited significant difference in the nodal efficiency and degree centrality analysis. The nodes A6mL and A6mR showed markable decrease in total four weightings in Ep group.Conclusion The hub nodes A6mL and A6mR, get disconnected in the patients with ISE, causing subsequent lower efficiency of global and regional network. The findings provide basis for presurgical assessment of ISE, for that caution should be taken when it involves hub nodes during intraoperative electrical stimulation.

Graph theoretical analysis of tau burden and the functional connectome in Alzheimers disease

2019 ◽  
Author(s):  
A Weller ◽  
GN Bischof ◽  
P Schlüter ◽  
N Richter ◽  
J Kukolja ◽  
...  
Keyword(s):  
Theoretical Analysis ◽  
Alzheimers Disease ◽  
Graph Theoretical Analysis ◽  
Functional Connectome

Quality of Location in Regions and Economic Efficiency of Private Companies in Poland

2013 ◽  
Vol 8 (2) ◽  
pp. 121-134
Author(s):  
Wioletta Wierzbicka
Keyword(s):  
Economic Efficiency ◽  
Strong Correlation ◽  
Location Factors ◽  
Lower Efficiency ◽  
Private Companies ◽  
Level Of Knowledge

Evaluation of the correlation between the economic efficiency level of private companies in Poland and the quality of location in the regions was the aim of the study. Based on the conducted analyses it was established that the level of sales markets absorptiveness shows the strongest correlation with the level of economic efficiency of the companies surveyed. The majority of regions characterised by absorptive sales markets also recorded good results in economic efficiency of companies located there while voivodships with low internal demand were characterised by definitely lower efficiency. Increasingly strong correlation was also recorded between the economic efficiency level of the companies surveyed and the level of knowledge in the regions. This may be the signal that currently the location factors of "soft" nature present increasing influence on the efficiency of companies and it is not impossible that their importance will continue increasing. 

scholarly journals Asymmetric Genome Organization in an RNA Virus Revealed via Graph-Theoretical Analysis of Tomographic Data

2015 ◽  
Vol 11 (3) ◽  
pp. e1004146 ◽  
Author(s):  
James A. Geraets ◽  
Eric C. Dykeman ◽  
Peter G. Stockley ◽  
Neil A. Ranson ◽  
Reidun Twarock
Keyword(s):  
Theoretical Analysis ◽  
Genome Organization ◽  
Rna Virus ◽  
Graph Theoretical Analysis ◽  
Tomographic Data

Multilag Correlation Estimators for Polarimetric Radar Measurements in the Presence of Noise

2012 ◽  
Vol 29 (6) ◽  
pp. 772-795 ◽  
Author(s):  
Lei Lei ◽  
Guifu Zhang ◽  
Richard J. Doviak ◽  
Robert Palmer ◽  
Boon Leng Cheong ◽  
...  
Keyword(s):  
Theoretical Analysis ◽  
Data Quality ◽  
Signal To Noise Ratio ◽  
Simulated Data ◽  
Radar Data ◽  
Polarimetric Radar ◽  
Signal To Noise ◽  
Spectral Moments ◽  
Radar Measurements

Abstract The quality of polarimetric radar data degrades as the signal-to-noise ratio (SNR) decreases. This substantially limits the usage of collected polarimetric radar data to high SNR regions. To improve data quality at low SNRs, multilag correlation estimators are introduced. The performance of the multilag estimators for spectral moments and polarimetric parameters is examined through a theoretical analysis and by the use of simulated data. The biases and standard deviations of the estimates are calculated and compared with those estimates obtained using the conventional method.

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