scholarly journals Gold Nanoparticles Functionalized with Mercaptosuccinic Acid as a Means for Detecting Fe(III) Ions

2021 ◽  
Vol 5 (1) ◽  
pp. 6
Author(s):  
Nadezhda S. Komova ◽  
Ksenya V. Serebrennikova ◽  
Anna N. Berlina ◽  
Svetlana M. Pridvorova ◽  
Anatoly V. Zherdev ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Colorimetric Detection ◽  
Capping Agent ◽  
Maximum Permissible Level ◽  
Mercaptosuccinic Acid ◽  
One Step ◽  
20 Nm ◽  
Drinking Water Samples ◽  
Dispersed Gold ◽  
Absorbance Spectra

The application of mercaptosuccinic acid-capped gold nanoparticles as a sensing probe for the colorimetric detection of Fe(III) is reported. The well-dispersed gold nanoparticles (AuNPs) with a diameter of around 20 nm were obtained by a one-step reaction of tetrachloroauratic acid with mercaptosuccinic acid (MSA) as a reducing and capping agent, respectively. Fe(III) reportedly causes the aggregation of prepared MSA-capped AuNPs followed by a change in color and a shift to long wavelengths in the absorbance spectra. The resulting method allows for a visual and spectrophotometric Fe(III) determination with detection limits of 30 ng/mL and 23 ng/mL, respectively. MSA-capped AuNPs have been used as sensing probes for the detection of Fe(III) in drinking water samples with a detection limit that is much lower than the maximum permissible level of Fe(III) specified by official regulations (300 ng/mL).

Preparation of Gold Nanoparticles in an Aqueous Medium Using 2-Mercaptosuccinic Acid as Both Reduction and Capping Agent

2008 ◽  
Vol 8 (4) ◽  
pp. 2062-2068 ◽  
Author(s):  
K. Vasilev ◽  
T. Zhu ◽  
G. Glasser ◽  
W. Knoll ◽  
M. Kreiter
Keyword(s):  
Electron Microscopy ◽  
Gold Nanoparticles ◽  
Particle Growth ◽  
Capping Agent ◽  
Mercaptosuccinic Acid ◽  
Vis Spectroscopy ◽  
One Step ◽  
Reaction In Water ◽  
Scanning Electron

Monolayer protected gold nanoparticles with diameters above 10 nm were prepared by a simple, one step reaction in water. 2-mercaptosuccinic acid (MSA) was used both as reduction agent for hydrogen tetrachloroaurate (HAuCl4) and as stabilizing agent for the gold nanoparticles. Size distribution and surface chemistry were investigated by UV-Vis spectroscopy, scanning electron microscopy and Fourier Transform Infrared Spectroscopy. Particle size can be controlled by adjusting the molar portions of the reactants. The resulting particles are efficiently stabilized against aggregation when MSA is used in a concentration of 40% and above. Below a minimum MSA concentration a long-term particle growth is observed.

One step alkaline synthesis of biocompatible gold nanoparticles using dextrin as capping agent

2010 ◽  
Vol 13 (7) ◽  
pp. 2843-2851 ◽  
Author(s):  
Michael J. Anderson ◽  
Edith Torres-Chavolla ◽  
Brian A. Castro ◽  
Evangelyn C. Alocilja
Keyword(s):  
Gold Nanoparticles ◽  
Capping Agent ◽  
One Step

Label-Free Colorimetric Detection of Prothioconazole Using Gold Nanoparticles Based on One-Step Reaction

2020 ◽  
Vol 6 (5) ◽  
pp. 2805-2811 ◽  
Author(s):  
Ying Zhou ◽  
Congdi Li ◽  
Rong Liu ◽  
Zenglong Chen ◽  
Li Li ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Colorimetric Detection ◽  
Label Free ◽  
One Step

Colorimetric Detection of Cadmium Ions Using DL-Mercaptosuccinic Acid-Modified Gold Nanoparticles

2016 ◽  
Vol 16 (1) ◽  
pp. 840-843 ◽  
Author(s):  
Na Chen ◽  
Jun Chen ◽  
Jing-Hua Yang ◽  
Lian-Yang Bai ◽  
Yu-Ping Zhang
Keyword(s):  
Gold Nanoparticles ◽  
Colorimetric Detection ◽  
Cadmium Ions ◽  
Mercaptosuccinic Acid

Anti-obesity Effect of Gold Nanoparticles from Dendropanax morbifera Léveille by Suppression of Triglyceride Synthesis and Downregulation of PPARγ and CEBPα Signaling Pathways in 3T3-L1 Mature Adipocytes and HepG2 Cells

2020 ◽  
Vol 16 (2) ◽  
pp. 196-203 ◽  
Author(s):  
Myoung Hi Yi ◽  
Shakina Yesmin Simu ◽  
Sungeun Ahn ◽  
Verónica Castro Aceituno ◽  
Chao Wang ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Fatty Liver ◽  
Lipid Accumulation ◽  
Hepg2 Cells ◽  
Cellular Level ◽  
Dendropanax Morbifera ◽  
Immunoblotting Assay ◽  
Triglyceride Content ◽  
20 Nm ◽  
Proliferation Assays

Background: Biosynthesis of gold nanoparticles from medicinal plants has become an interesting strategy in biomedical research due to its exclusive properties including less toxic cellular level through its ecofriendly biological function. Objective: To examine the anti-lipid accumulation effect of spherical gold nanoparticles (size 10-20 nm) synthesized from Dendropanax morbifera Léveille (D-AuNPs) in both 3T3-L1 and HepG2 cells. Method: 3T3-L1 preadipocytes and HepG2 hepatocytes were stimulated with cocktail media to generate obese and fatty liver disease models. Cell cytotoxicity and cell proliferation assays were performed in adipocytes at different stages of growth. An anti-lipid accumulation assay was performed in 3T3-L1 obese and HepG2 fatty liver models using different doses of D-AuNPs. Expression of adipogenic genes of PPARγ, CEBPα, Jak2, STAT3, and ap2 and hepatogenic genes PPARα, FAS, and ACC was measured by real-time PCR. In addition, protein expression of PPARγ and CEBPα was evaluated by immunoblotting assay. Result: We found that D-AuNPs (size 10–20 nm) at concentrations up to 100 µg/ml were nontoxic to 3T3-L1 and HepG2 at post-confluent and mature stages. In addition, pretreatment of D-AuNPs at post-confluent stage reduced triglyceride content. In addition, the adipogenesis process was negatively controlled by D-AuNPs, with downregulated PPARγ, CEBPα, Jak2, STAT3, and ap2 expression in 3T3-L1 cells and FAS and ACC levels in HepG2 cells. Conclusion: These data indicated that D-AuNPs exert antiadipogenic properties. We hypothesize that Dendropanax contains a large amount of phenolic compound that coats the surface of gold nanoparticles and has the ability to reduce the excess amount of lipid in both cell lines.

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