scholarly journals Musculoskeletal Soft-Tissue Sarcoma: Quality Assessment of Initial MRI Reports Shows Frequent Deviation from ESSR Guidelines

Diagnostics ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 695
Author(s):  
Sebastian Weiss ◽  
Alexander Korthaus ◽  
Nora Baumann ◽  
Jin Yamamura ◽  
Alexander S. Spiro ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcomas ◽  
Quality Criteria ◽  
Final Diagnosis ◽  
Tissue Mass ◽  
Musculoskeletal Radiology ◽  
Radiology Reports ◽  
Patients At Risk ◽  
Magnetic Resonance Imaging Mri ◽  
The Masses

Soft-tissue sarcomas (STS) are a rare subtype of soft-tissue mass and are frequently misinterpreted as benign lesions. Magnetic resonance imaging (MRI) is the primary recommended type of diagnostics. To assess the quality of primary radiology reports, we investigated whether recommended MRI report elements were included in compliance with European Society of Musculoskeletal Radiology (ESSR) guidelines. A total of 1107 patients were evaluated retrospectively, and 126 radiological reports on patients with malignant STS were assessed for ESSR quality criteria. One or more required sequences or planes were missing in 67% of the reports. In all 126 cases, the report recognized the mass as anomalous (100%). Sixty-eight percent of the reports mentioned signs of malignancy. The majority of reports (n = 109, 87%) articulated a suspected diagnosis, 32 of which showed a mismatch with the final diagnosis (25%). Thirty-two percent of the reports had a misinterpretation of the masses as benign. Benign misinterpretations were more common in masses smaller than 5 cm (65% vs. 27%). Thirty percent of the reports suggested tissue biopsy and 6% recommended referral to a sarcoma center. MRI reports showed frequent deviations from ESSR guidelines, and protocol guidelines were not routinely met. Deviations from standard protocol and reporting guidelines could put patients at risk for inadequate therapy.

scholarly journals Dural Plasmacytoma Involving Calvarium with Soft Tissue Extension Mimicking Meningioma: A Diagnostic Dilemma

2019 ◽  
Vol 08 (01) ◽  
pp. 053-056
Author(s):  
Anju Shukla ◽  
Devendra Chhabra ◽  
Tarun Pandey ◽  
Prashant Singh
Keyword(s):  
Soft Tissue ◽  
Postoperative Radiotherapy ◽  
Parietal Bone ◽  
Diagnostic Dilemma ◽  
Tissue Mass ◽  
Soft Tissue Extension ◽  
Dural Tail ◽  
Left Parietal Bone ◽  
Magnetic Resonance Imaging Mri

AbstractHere, the authors describe a case of 25-year-old man diagnosed with dural plasmacytoma involving calvarium with soft tissue extension. Magnetic resonance imaging (MRI) revealed extra-axial heterogeneously enhancing soft tissue mass lesion in the left parieto-occipital region with a dural tail mimicking meningioma, destroying the left parietal bone, and bulging into the scalp. Mass was excised and histopathologic examination revealed plasmacytoma with amyloid deposition. There is no recurrence after postoperative radiotherapy and 2 years of follow-up, although the future course is still not certain. The clinician should consider alternative diagnosis other than meningioma prior to proceeding to surgery if the dural-based lesion is involving calvarium and soft tissue extension.

Intermuscular lipomas of the thigh region in dogs: 11 cases

1999 ◽  
Vol 35 (2) ◽  
pp. 165-167 ◽  
Author(s):  
MJ Thomson ◽  
SJ Withrow ◽  
WS Dernell ◽  
BE Powers
Keyword(s):  
Soft Tissue ◽  
Surgical Resection ◽  
Soft Tissue Sarcomas ◽  
Full Length ◽  
Time Of Surgery ◽  
The Masses ◽  
Thigh Region

Ten dogs with intermuscular lipomas in the thigh region were treated by surgical resection. The masses were located predominantly between the semitendinosus and semimembranosus muscles and involved the full length of the femur. These lipomas were not infiltrative but located deep between the fascial planes of the associated muscles. These tumors can appear similar to soft-tissue sarcomas in this location, but they can be differentiated by cytology and histology. Differentiation from an infiltrative lipoma is predominantly determined at the time of surgery. No tumors recurred in the median follow-up period of 17 months.

Improving care quality for patients with soft tissue and bone sarcoma by establishing a national virtual tumor board and electronic consultation platform.

2016 ◽  
Vol 34 (7_suppl) ◽  
pp. 211-211
Author(s):  
Minggui Pan ◽  
Andrew Fang ◽  
Maihgan Kavanagh ◽  
Brian Kim ◽  
Jason D Lee ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Soft Tissue Sarcomas ◽  
Bone Sarcoma ◽  
Care Quality ◽  
Tumor Board ◽  
Optimal Care ◽  
Kaiser Permanente ◽  
Musculoskeletal Radiology ◽  
Electronic Consultation

211 Background: Bone and soft tissue sarcomas are relatively uncommon and their management is extremely complex requiring coordinated multidisciplinary expertise for optimal care. Because Kaiser Permanente operates across many geographic regions in the country, in-person tumor board is not practical. Methods: The Kaiser Permanente Northern California medical oncology team has developed a system-based virtual tumor board (VTB) and electronic consultation (EC) platform comprised of experts from several key disciplines including musculoskeletal/surgical oncology, musculoskeletal radiology, pathology, radiation oncology, brachytherapy, medical adult and pediatric oncology. The VTB and EC cases are physician referral-based. The VTB occurs once every two weeks via video conferencing reviewing imaging studies and pathology while EC is available for more urgent cases whenever requested. This platform is available to Kaiser Permanente physicians in Northern and Southern California and other states including Hawaii, Mid-Atlantic, Northwest, Colorado, and Georgia. We conducted a survey targeting referring physicians to assess the value of this service platform in improving sarcoma care. Results: From March 2013 to October 2015, approximately 500 cases have been referred to the VTB and EC. Approximately 2/3 of the cases were referred to the VTB and 1/3 to the EC. The cases include a vast spectrum of bone and soft tissue sarcoma cases that were either newly diagnosed or at the time of relapse or progression. The physician survey on the quality and utilization of this sarcoma platform provided very positive feedback, with 100% responses stating that VTB and EC improved patient care and their confidence in managing patients with sarcoma, 90% stating VTB and EC changed their management to a certain extent. Approximately 90% responders rated VTB and EC very to extremely helpful. Conclusions: We conclude that a system-based VTB and EC can provide an excellent platform for improving quality of care and physician confidence in managing patients with bone and soft tissue sarcoma in an integrated healthcare system.

scholarly journals ‘‘Two-Week Waits’’—Are They Leading to Earlier Diagnosis of Soft-Tissue Sarcomas?

Sarcoma ◽  
2010 ◽  
Vol 2010 ◽  
pp. 1-3 ◽  
Author(s):  
W. St. J. Taylor ◽  
R. J. Grimer ◽  
S. R. Carter ◽  
R. M. Tillman ◽  
A. Abudu ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Mass ◽  
Soft Tissue Sarcomas ◽  
Malignant Tumours ◽  
Tissue Mass ◽  
Borderline Lesion ◽  
Average Size ◽  
Malignant Diagnosis ◽  
Malignant Soft Tissue

Introduction. The ‘‘two-week wait’’ was established as a potential means of diagnosing malignant tumours earlier. This paper investigated whether these clinics are leading to earlier diagnosis of malignant soft-tissue lumps.Method. We identified all referrals to our centre from a database over a 4-year period.Results. 2225 patients were referred to our unit for investigation of a soft-tissue mass. 576 (26%) were referred under the ‘‘two-week wait’’ criteria. 153 (27%) of which were found to have a malignant or borderline malignant diagnosis. 1649 patients were referred nonurgently. 855 (52%) of which were diagnosed with a malignant or borderline lesion. The average size at diagnosis was 9.4 cm with no difference in size between the different referral routes.Conclusion. There is little evidence that the two-week wait clinic is leading to earlier diagnosis of soft-tissue sarcomas with the majority still being referred nonurgently.

Detection of local recurrences of limb soft-tissue sarcomas: Is magnetic resonance imaging (MRI) relevant?

2009 ◽  
Vol 27 (15_suppl) ◽  
pp. 10582-10582
Author(s):  
G. Ferron ◽  
R. Aziza ◽  
M. Delannes ◽  
T. Filleron ◽  
B. Marquès ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Soft Tissue ◽  
Clinical Examination ◽  
Soft Tissue Sarcomas ◽  
Adult Patients ◽  
Resonance Imaging ◽  
Local Recurrences ◽  
Magnetic Resonance Imaging Mri ◽  
Mri Surveillance

10582 Background: The role of systematic magnetic resonance imaging (MRI) surveillance after resection of soft-tissue sarcomas (STS) of the limb is opened to debate. The aim of our study was to retrospectively evaluate the effectiveness of a MRI surveillance schedule performed in adult patients. Methods: 124 adult patients have been treated from 1996 to 2006 for a non-metastatic limb STS at our centre: 86 patients (70%) had clear resection margins (R0) and 111 patients (90%) received an adjuvant radiotherapy. 663 MRI examinations were performed, with a median of 5 per patient [range: 1 to 5]. The rythm of surveillance schedule was respected in 57% of the examinations. Results: Forty-one patients (33%) prematurely withdrew from the planned radiological surveillance due to metastasis diagnosis (15 cases), 5-year remission duration (5 cases), other reasons (12 cases), and drop out (9 cases). Among the 11 local recurrences (9%) which were observed, MRI was able to detect only 2 asymptomatic local recurrences, 1 with and 1 without synchronous metastasis, both had microscopically involved margins (R1). In contrast, MRI showed 11 false-positive cases. As the predictive positive value of MRI was 42%, clinical surveillance seems to be more effective. The evaluation of the cost of the systematic MRI surveillance is 200,000 euros. Clinical examination failed in 2 cases (2 asymptomatic local recurrences detected by MRI) as did MRI surveillance (2 false negative cases). In our study, cost-effectiveness was better with clinical examination than MRI surveillance. Conclusions: As observed in our study, systematic MRI surveillance is not relevant for the follow-up of all limb soft-tissue sarcomas. A prospective study could be promoted to evaluate the MRI surveillance of patient at high risk of local recurrence. No significant financial relationships to disclose.

scholarly journals Peripheral soft tissue Ewing’s sarcoma: a rare case report

2014 ◽  
Vol 7 (2) ◽  
pp. 43-46
Author(s):  
Farzana Shegufta ◽  
Mahfuz Ara Ferdousi ◽  
Md Abu Taher
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Mass ◽  
Left Forearm ◽  
Tissue Mass ◽  
X Ray ◽  
Intensity Lesion ◽  
Rare Case Report ◽  
Spectral Doppler ◽  
Bony Involvement ◽  
Magnetic Resonance Imaging Mri

A 22 years male patient presented with gradual left forearm swelling for 6 months. X ray forearm revealed large soft tissue swelling with tiny calcification and mild scalloping at inner aspect of ulna and ultrasonogram (USG) revealed soft tissue mass having calcification and necrotic areas within and spectral Doppler showed arterial type of blood flow with no augmentation. Later computerized tomography (CT) scan showed soft tissue mass with necrotic area and calcification with no bony involvement. Magnetic resonance imaging (MRI) with contrast revealed a large heterogeneously enhancing lobulated mixed intensity lesion in antero-medial compartment of the left forearm involving flexor group of muscles causing displacement of fat plane. MRI and subsequent histopathology of the lesion revealed it as a rare soft tissue Ewing’s sarcoma / primitive neuroectodermal tumor (PNET) in extremity. DOI: http://dx.doi.org/10.3329/imcj.v7i2.20113 Ibrahim Med. Coll. J. 2013; 7(2): 43-46

scholarly journals Soft Tissue Sarcoma: An Insight on Biomarkers at Molecular, Metabolic and Cellular Level

Cancers ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 3044
Author(s):  
Serena Pillozzi ◽  
Andrea Bernini ◽  
Ilaria Palchetti ◽  
Olivia Crociani ◽  
Lorenzo Antonuzzo ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcomas ◽  
Predictive Biomarkers ◽  
Cellular Level ◽  
Comprehensive Overview ◽  
Novel Treatments ◽  
Patients At Risk ◽  
Prognostic Stratification ◽  
Biomarker Research ◽  
Metabolic Biomarkers

Soft tissue sarcomas (STSs) are a heterogeneous group of rare tumors. Although constituting only 1% of all human malignancies, STSs represent the second most common type of solid tumors in children and adolescents and comprise an important group of secondary malignancies. Over 100 histologic subtypes have been characterized to date (occurring predominantly in the trunk, extremity, and retroperitoneum), and many more are being discovered due to molecular profiling. STS mortality remains high, despite adjuvant chemotherapy. New prognostic stratification markers are needed to help identify patients at risk of recurrence and possibly apply more intensive or novel treatments. Recent scientific advancements have enabled a more precise molecular characterization of sarcoma subtypes and revealed novel therapeutic targets and prognostic/predictive biomarkers. This review aims at providing a comprehensive overview of the most relevant cellular, molecular and metabolic biomarkers for STS, and highlight advances in STS-related biomarker research.

Microsurgical Management of Early Onset Alveolar Soft Part Sarcoma of the Oral Tongue: Case Report and Review of the Literature

2021 ◽  
pp. 000348942110212
Author(s):  
Jacob C. Lucas ◽  
Omar A. Karadaghy ◽  
Brian Andrews ◽  
Elizabeth Friedman ◽  
Kiran Kakarala ◽  
...  
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Soft Part ◽  
Soft Tissue Sarcomas ◽  
Alveolar Soft Part Sarcoma ◽  
Microvascular Reconstruction ◽  
Retrospective Case ◽  
Tissue Mass ◽  
Radial Forearm ◽  
Posterior Tongue

Objectives: Alveolar soft part sarcoma is a rare subset of soft tissue sarcomas, typically presenting in subjects 15 to 35 years of age. Usual presentation sites are the trunk, extremities, and the head and neck. Subjects younger than 5 years are rarely affected. Methods: In this retrospective case report, we present a 16-month old male with a rapidly growing soft tissue mass of the anterior and posterior tongue, found to be alveolar soft part sarcoma. Results: The subject was treated with primary surgical resection and the resulting defect was reconstructed with a radial forearm free flap. Conclusions: To our knowledge, this is the youngest subject to have been diagnosed with alveolar soft part sarcoma. Surgical extirpation and microvascular reconstruction were successful, and the patient remains disease free 4 years post-operatively.

scholarly journals Sporadic Retroperitoneal Hemangioblastoma: Report of a Case and Review of the Literature

2017 ◽  
Vol 2017 ◽  
pp. 1-5
Author(s):  
F. G. Jalikis ◽  
B. L. Hoch ◽  
R. Bakthavatsalam ◽  
M. I. Montenovo
Keyword(s):  
Differential Diagnosis ◽  
Soft Tissue ◽  
Soft Tissue Mass ◽  
Final Diagnosis ◽  
Rare Tumor ◽  
Review Of The Literature ◽  
Tissue Mass ◽  
Pathologic Features

We report a case of sporadic isolated hemangioblastoma arising from the retroperitoneum and provide a review of the scarce literature regarding this very rare tumor. Furthermore, we thoroughly describe the pathologic features and the broad differential diagnosis that should always be included in the study of any retroperitoneal soft tissue mass to arrive at the final diagnosis.

scholarly journals Giant Soft Tissue Sarcoma of Scalp with Skull and Cerebral Invasion

2021 ◽  
Vol 23 (4) ◽  
pp. 357-359
Author(s):  
Raghav Yelamanchi ◽  
Parikshith Manjunath ◽  
Nikhil Gupta ◽  
CK Durga
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Malignant Tumors ◽  
Soft Tissue Sarcomas ◽  
Brain Parenchyma ◽  
Clinical Image ◽  
Tissue Mass ◽  
Surgical Department ◽  
Pleomorphic Sarcoma ◽  
Multimodality Approach

Scalp soft tissue sarcomas (STS) are very rare accounting for less than 0.1% of all malignancies. We report a rare clinical image of advanced stage soft tissue sarcoma of the scalp. A 65 year woman had presented to the surgical department with complaints of a rapidly growing swelling over the scalp for three months. On examination there was huge 20 x 20 cm swelling over the scalp in the left temporoparietal region with variegated consistency. Computed tomography of head revealed a large soft tissue mass with necrosis invading the bone and underlying brain parenchyma. Histopathological finding from core needle biopsy revealed pleomorphic sarcoma. STS are highly malignant tumors which should be diagnosed and treated using multimodality approach. Recurrences are common even after complete resection and prognosis is poor.

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