scholarly journals Biochemical and Hematological Relationship with the Evaluation of Autonomic Dysfunction by Heart Rate Recovery in Patients with Asthma and Type 2 Diabetes

Diagnostics ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 2187
Author(s):  
O. Gamaliel Aztatzi-Aguilar ◽  
Claudia Vargas-Domínguez ◽  
Yazmin Debray-Garcia ◽  
Manolo S. Ortega-Romero ◽  
Paloma Almeda-Valdés ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Heart Rate ◽  
Oxygen Saturation ◽  
Cell Count ◽  
Autonomic Dysfunction ◽  
Heart Rate Recovery ◽  
Low Cost ◽  
Clinical Settings ◽  
Red Cell Count

There are several methods to assess the function of the autonomic nervous system. Among them, heart rate recovery (HRR) is an accepted, easy, low-cost technique. Different pathological conditions have been related to the development of autonomic dysfunction. Our study aimed to evaluate the relationship between HRR and HRR-derived parameters in ambulatory patients with asthma or type 2 diabetes followed at the National Institutes of Health in Mexico City. A total of 78 participants, 50 women and, 28 men were enrolled; anthropometric, respiratory evaluations, and fasting blood samples were taken before participants performed a 6-min walking test (6MWT). Abnormal HRR was defined as a drop of ≤8 and ≤11 beats/min at 1 or 2 min and correlated negatively with basal oxygen saturation at 1 min. Heart rate at 1 min, correlated negatively with final oxygen saturation (p < 0.01). Statistically significant negative correlations were also observed between red cell count and white blood cell count and HOMA-IR with a p < 0.01. Since discrete hematological but significant changes correlated with HRR and HRR-derived parameters, we consider that these measures are helpful in clinical settings to identify subclinical autonomic dysfunction that permits us to prevent or anticipate chronic and fatal clinical outcomes.

scholarly journals Effect of Deep Relaxation Technique on Cardiac Autonomic Dysfunction in Type 2 Diabetes Mellitus

2018 ◽  
Vol 13 (1) ◽  
pp. 22-28 ◽  
Author(s):  
Farhana Rahman ◽  
Sultana Ferdousi
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Heart Rate ◽  
Type 2 Diabetes Mellitus ◽  
Autonomic Dysfunction ◽  
Time Domain ◽  
Autonomic Nerve ◽  
Nerve Function ◽  
Autonomic Nerve Function

Background: Type 2 Diabetes Mellitus (T2DM) may be associated with autonomic dysfunction. Performance of deep relaxation technique (DRT) may cause upturn of this deranged nerve function.Objective: To evaluate the impact of DRT on cardiac autonomic nerve function by analysis of time domain series of Heart Rate Variability (HRV) in T2DM patients.Methods: This prospective study was carried out on 30 female T2DM patients aged 50-55 years with duration of diabetes of 5-10 years enrolled from the Out Patient Department of Endocrinology, Bangabandhu Sheikh Mujib Medical University, Dhaka. They performed DRT (20 minutes twice daily) for 3 months. Thirty apparently healthy female with similar age who did not perform DRT or any other form of exercise, were included as control. To assess the cardiac autonomic nerve function, time domain measures of HRV of all subjects were recorded by a data acquisition device Power Lab (Australia). HRV data of all subjects were collected at baseline (pre) and also after 3 months(Post). For statistical analysis, paired and independent sample t-test were used.Results: The pre-intervention values of resting HR was significantly higher (p<0.001) and mean R-R interval, SDRR, CVRR, SDSD, RMSSD and pRR50% were significantly lower (p<0.001) in all diabetic patients compared to control. After 3 months of DRT, there was significant decrement in resting mean heart rate (p<0.01) and significant increment in mean R-R interval, SDRR, CVRR, SDSD, RMSSD and pRR50% (p<0.001) compared to their pre-intervention values.Conclusion: Cardiac autonomic nerve dysfunction may occur in T2DM and 3 months regular practice of DRT mayy significantly improv cardiac autonomic nerve function with parasympathetic dominance.J Bangladesh Soc Physiol. 2018, June; 13(1): 22-28

scholarly journals Heart Rate Recovery After Exercise Is a Predictor of Silent Myocardial Ischemia in Patients With Type 2 Diabetes

Diabetes Care ◽  
2011 ◽  
Vol 34 (3) ◽  
pp. 724-726 ◽  
Author(s):  
T. Yamada ◽  
T. Yoshitama ◽  
K. Makino ◽  
T. Lee ◽  
F. Saeki
Keyword(s):  
Type 2 Diabetes ◽  
Heart Rate ◽  
Myocardial Ischemia ◽  
Heart Rate Recovery ◽  
Silent Myocardial Ischemia

Heart rate recovery after exercise and incidence of type 2 diabetes in men

2009 ◽  
Vol 19 (3) ◽  
pp. 189-192 ◽  
Author(s):  
Sae Young Jae ◽  
Mercedes R. Carnethon ◽  
Kevin S. Heffernan ◽  
Bo Fernhall ◽  
Moon-Kyu Lee ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Heart Rate ◽  
Heart Rate Recovery

scholarly journals EVALUATION OF AUTONOMIC DYSFUNCTION BY HEART RATE VARIABILITY ANALYSIS IN TYPE 2 DIABETES MELLITUS

2016 ◽  
Vol 10 (1) ◽  
pp. 309
Author(s):  
Phurpa Nil Nil ◽  
Sultana - Ferdousi
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Type 2 Diabetes Mellitus ◽  
Autonomic Neuropathy ◽  
Autonomic Dysfunction ◽  
Cardiac Autonomic Neuropathy ◽  
Heart Rate Variability Analysis

ABSTRACTObjective: Cardiac autonomic neuropathy (CAN) is a severe and common, yet highly underdiagnosed, complication of Type 2 diabetes mellitus(T2DM). Subclinical CAN may have reduced heart rate variability (HRV) but normal Ewing battery test. This study was performed to evaluate theimportance of 5 minutes HRV for the detection of autonomic dysfunction in T2DM without (CAN-T2DM).Methods: This cross-sectional observational study was conducted at the Department of Physiology, Bangabandhu Sheikh Mujib Medical University(BSMMU) on 30 recently diagnosed T2DM (RT2DM) and 54 long-term CAN-male T2DM patients (LT2DM), aged 45-55 years, from the EndocrinologyOut Patient Department of BSMMU, Dhaka. 30 age and body mass index matched apparently healthy male subjects were control. Ewing battery testwas used to rule out CAN positive T2DM. HRV data were recorded by a polyrite-D and analyzed by software. HRV was assessed by time domainmethod. For statistical analysis, ANOVA and unpaired t-test were used.Results: Mean RR, standard deviation of NN intervals (SDNN) (p<0.05), and root mean square of the successive differences (RMSSD) were significantly(p<0.001) lower, and mean HR and SDNN/RMSSD were (p<0.001) significantly higher in LT2DM compared to RT2DM and control. In addition, SDNNwas also significantly (p<0.05) lower in RT2DM than that of control.Conclusions: Results conclude that autonomic dysfunction may occur in both LT2DM and RT2DM patients without neuropathy and 5 minutes HRVtest is an important tool for detecting subclinical CAN.Keywords: Type 2 diabetes mellitus, Cardiac autonomic neuropathy, Heart rate variability.

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