Periodontitis and diabetes mellitus combine systemic condition and dental health and can cause salivary alterations. This work examined the saliva of 16 individuals with type II diabetes mellitus (DM) and severe chronic periodontitis (SCP) (G1), 11 with DM and without SCP (G2), 14 without DM with SCP (G3) and 15 without DM and without SCP (G4). The periodontal condition was evaluated, salivary flow and buffering capacity were analyzed and salivary components were measured using commercial kits. Diabetics with SCP showed a tendency to decrease the flow. The buffering capacity remains unchanged. Urea (p < 0.018) and total protein (p < 0.001) were larger and less Calcium was observed (p < 0.0001) in diabetics. In patients with SCP, the DM favored even greater urea increase. The phosphate increased in groups G1, G2 and G3 (p < 0.0001) compared to G4. The metabolism from diabetics with SCP increases salivary proteins, increasing urea resulting from amino acids degradation by periodontal bacterias.
Effect of NonSurgical Periodontal Therapy on Plasma Levels of IL-17 in Chronic Periodontitis Patients with Well Controlled Type-II Diabetes Mellitus—A Clinical Study