scholarly journals Expression of apelin among the individuals of chronic periodontitis, with and without type ii diabetes mellitus: A study using enzyme-linked immunosorbent assay

2020 ◽  
Vol 10 (3) ◽  
pp. 182
Author(s):  
Santosh Kumar ◽  
Tanvi Hirani ◽  
Viral Patel ◽  
Sagar Hirani ◽  
Irfan Mohammed ◽  
...  
Author(s):  
Júlia Dias Magalhães ◽  
Camila Barreto dos Santos Tolomei ◽  
Roberta Santos Tunes ◽  
Urbino da Rocha Tunes ◽  
Márcia Tosta Xavier

Periodontitis and diabetes mellitus combine systemic condition and dental health and can cause  salivary alterations. This work examined the saliva of 16 individuals with type II diabetes mellitus (DM) and severe chronic periodontitis (SCP) (G1), 11 with DM and without SCP (G2), 14 without DM with SCP (G3) and 15 without DM and without SCP (G4). The periodontal condition was evaluated, salivary flow and buffering capacity were analyzed and salivary components were measured using commercial kits. Diabetics with SCP showed a tendency to decrease the flow. The buffering capacity remains unchanged. Urea (p < 0.018) and total protein (p < 0.001) were larger and less Calcium was observed (p < 0.0001) in diabetics. In patients with SCP, the DM favored even greater urea increase. The phosphate increased in groups G1, G2 and G3 (p < 0.0001) compared to G4. The metabolism from diabetics with SCP increases salivary proteins, increasing urea resulting from amino acids degradation by periodontal bacterias.


Author(s):  
SARVODAYA VAISHNAVI RATHEESH ◽  
SANGEETHA SUBRAMANIAN ◽  
DAYANAND JOHN VICTOR ◽  
PRAKASH PONNUDURAI SAMUEL GNANA

2011 ◽  
Vol 2 (1) ◽  
pp. 12 ◽  
Author(s):  
Savita Sambashivaiah ◽  
Shivaprasad Bilichodmath ◽  
Nanjammanni Nanjaiah ◽  
Rithesh Kulal

This randomized controlled study evaluated the association of Helicobacter pylori (H. pylori) with chronic periodontitis patients with and without type II Diabetes Mellitus. H. pylori is considered to be a pathogen responsible for gastritis, peptic ulcers and a risk factor for gastric cancer. The aim of the present study was to evaluate the association of H. pylori with chronic periodontitis patients with and without type II diabetes mellitus before and after treatment. The prevalence of H. pylori in periodontal pockets was determined by rapid urease test in a 36 patients, which were grouped as Group 1 (Healthy subjects), Group II (chronic periodontitis patients) and Group III (Chronic periodontitis patients with Type II Diabetes Mellitus), 12 in each group before treatment by collecting plaque samples. After treatment, 12 plaque samples were collected and prevalence H. pylori was detected. Group II and Group III had a significantly higher rate of positive results for H. pylori compared to healthy subjects before treatment. After treatment, H. pylori were not detected in Group II and in Group III Only one of 12 chronic periodontitis patients with Type II diabetes mellitus had H. pylori in the periodontal pocket. The prevalence of H. pylori did not differ significantly between the chronic periodontitis patients with and without type II diabetes mellitus. Meticulous scaling and root planning will reduce the prevalence of H. pylori in periodontal pockets.


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