scholarly journals Effects of Lipoic Acid on Immune Function, the Antioxidant Defense System, and Inflammation-Related Genes Expression of Broiler Chickens Fed Aflatoxin Contaminated Diets

2014 ◽  
Vol 15 (4) ◽  
pp. 5649-5662 ◽  
Author(s):  
Yan Li ◽  
Qiu-Gang Ma ◽  
Li-Hong Zhao ◽  
Hua Wei ◽  
Guo-Xiang Duan ◽  
...  
Keyword(s):  
Immune Function ◽  
Lipoic Acid ◽  
Broiler Chickens ◽  
Antioxidant Defense ◽  
Antioxidant Defense System ◽  
Defense System ◽  
Genes Expression

Efficacy of DL-α lipoic acid against systemic inflammation-induced mice: antioxidant defense system

2008 ◽  
Vol 313 (1-2) ◽  
pp. 113-123 ◽  
Author(s):  
E. Philip Jesudason ◽  
J. Gunasingh Masilamoni ◽  
Charles E. Jebaraj ◽  
Solomon F. D. Paul ◽  
R. Jayakumar
Keyword(s):  
Systemic Inflammation ◽  
Lipoic Acid ◽  
Antioxidant Defense ◽  
Antioxidant Defense System ◽  
Defense System

scholarly journals Dose-Dependent Protection by Lipoic Acid against Cisplatin-Induced Nephrotoxicity in Rats: Antioxidant Defense System

2008 ◽  
Vol 86 (5) ◽  
pp. 234-241 ◽  
Author(s):  
Satu M. Somani ◽  
Kazim Husain ◽  
Craig Whitworth ◽  
Gary L. Trammell ◽  
Mokenge Malafa ◽  
...  
Keyword(s):  
Lipoic Acid ◽  
Antioxidant Defense ◽  
Antioxidant Defense System ◽  
Defense System ◽  
Dose Dependent

Dose-Dependent Protection by Lipoic Acid against Cisplatin-Induced Nephrotoxicity in Rats: Antioxidant Defense System

2000 ◽  
Vol 86 (5) ◽  
pp. 234-241 ◽  
Author(s):  
Satu M. Somani ◽  
Kazim Husain ◽  
Craig Whitworth ◽  
Gary L. Trammell ◽  
Mokenge Malafa ◽  
...  
Keyword(s):  
Lipoic Acid ◽  
Antioxidant Defense ◽  
Antioxidant Defense System ◽  
Defense System ◽  
Dose Dependent

scholarly journals Impairment of liver antioxidant defense activity of broiler chickens exposed to benzo[α]pyrene

2011 ◽  
Vol 35 (1) ◽  
pp. 81-87
Author(s):  
I. K. Latif
Keyword(s):  
Oxidative Stress ◽  
Superoxide Dismutase ◽  
Glutathione Peroxidase ◽  
Broiler Chickens ◽  
Antioxidant Defense ◽  
Antioxidant Defense System ◽  
Defense System ◽  
Exogenous Compounds

gainst damage initiated by a variety of endogenous and exogenous compounds. This study was conducted to evaluate the influence of Benzo[α]Pyrene (BαP) administration on the liver antioxidant defense system. Chicks were assigned into five equal groups, as control, tricaprylin group and three groups treated with BαP (1.5 μg, 150 μg or 15 mg/kg BW). Five birds were sacrificed at days 7, 14, 21 and 35 from each group. To assess the liver antioxidant defense system, glutathione (GSH) concentration, glutathione peroxidase (GSH-Px), superoxide dismutase (SOD) and catalase (CAT) activities were employed. It was found that 15 mg of BαP level create significant increase (P<0.05) in the GSH level, GSH-Px, SOD and CAT activities (18.483, 9.88, 69.44 and 89.88 respectively) of broilers at day 7 post-instillation (p.i.) in compared with control (12.392, 6.51, 41.08 and 50.83). Nevertheless, significant decrease (P<0.05) in the GSH level, GSH-Px, SOD and CAT activities at 21 and 35 days. A key finding from this study is that exposure to BαP may induces oxidative stress on the liver and impair the antioxidant defense system in broilers.

Oxidative stress on mitochondrial antioxidant defense system in the aging process: Role of dl-α-lipoic acid and l-carnitine

2005 ◽  
Vol 355 (1-2) ◽  
pp. 173-180 ◽  
Author(s):  
Sethumadhavan Savitha ◽  
Jayavelu Tamilselvan ◽  
Muthuswamy Anusuyadevi ◽  
Chinnakannu Panneerselvam
Keyword(s):  
Oxidative Stress ◽  
Lipoic Acid ◽  
Aging Process ◽  
Antioxidant Defense ◽  
Antioxidant Defense System ◽  
Defense System
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