scholarly journals Dose dependent protection by lipoic acid against cisplatin-induced ototoxicity in rats: antioxidant defense system

1999 ◽  
Vol 47 (2) ◽  
pp. 195-202 ◽  
Author(s):  
L. Rybak
Keyword(s):  
Lipoic Acid ◽  
Antioxidant Defense ◽  
Antioxidant Defense System ◽  
Defense System ◽  
Dose Dependent

scholarly journals Dose-Dependent Protection by Lipoic Acid against Cisplatin-Induced Nephrotoxicity in Rats: Antioxidant Defense System

2008 ◽  
Vol 86 (5) ◽  
pp. 234-241 ◽  
Author(s):  
Satu M. Somani ◽  
Kazim Husain ◽  
Craig Whitworth ◽  
Gary L. Trammell ◽  
Mokenge Malafa ◽  
...  
Keyword(s):  
Lipoic Acid ◽  
Antioxidant Defense ◽  
Antioxidant Defense System ◽  
Defense System ◽  
Dose Dependent

Dose-Dependent Protection by Lipoic Acid against Cisplatin-Induced Nephrotoxicity in Rats: Antioxidant Defense System

2000 ◽  
Vol 86 (5) ◽  
pp. 234-241 ◽  
Author(s):  
Satu M. Somani ◽  
Kazim Husain ◽  
Craig Whitworth ◽  
Gary L. Trammell ◽  
Mokenge Malafa ◽  
...  
Keyword(s):  
Lipoic Acid ◽  
Antioxidant Defense ◽  
Antioxidant Defense System ◽  
Defense System ◽  
Dose Dependent

Efficacy of DL-α lipoic acid against systemic inflammation-induced mice: antioxidant defense system

2008 ◽  
Vol 313 (1-2) ◽  
pp. 113-123 ◽  
Author(s):  
E. Philip Jesudason ◽  
J. Gunasingh Masilamoni ◽  
Charles E. Jebaraj ◽  
Solomon F. D. Paul ◽  
R. Jayakumar
Keyword(s):  
Systemic Inflammation ◽  
Lipoic Acid ◽  
Antioxidant Defense ◽  
Antioxidant Defense System ◽  
Defense System

scholarly journals Nicotine-Induced Oxidative Stress in Human Primary Endometrial Cells

2019 ◽  
Vol 38 (3) ◽  
pp. 202-208 ◽  
Author(s):  
Fatemeh Khademi ◽  
Hamidreza Totonchi ◽  
Neda Mohammadi ◽  
Razieh Zare ◽  
Fatemeh Zal
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Defense ◽  
Antioxidant Defense System ◽  
Dependent Manner ◽  
Direct Effects ◽  
Defense System ◽  
Endometrial Cells ◽  
Nicotine Administration ◽  
Dose Dependent ◽  
Oxidative State

Nicotine is a major component of tobacco plants and is responsible for the development of reproductive problems in smokers. Nicotine has been recognized to result in oxidative stress by inducing the generation of reactive oxygen species (ROS) in some parts of female reproductive system, but the effect of nicotine on endometrium that plays an important role in reproductive biology stays unexplored. The aim of this work was to clarify the direct effects of nicotine administration on the antioxidant defense system and lipid peroxidation in human endometrial cells. Human endometrial stromal primary cells were treated with nicotine (0, 10−11, 10−8, and 10−6 M) for 24 hours. On nicotine administration, the endometrial cells were associated with a decrease in antioxidant defense markers such as Glutathione (GSH) level, glutathione peroxidase (GPx), glutathione reductase (GR), and catalase (CAT) enzymes activity and higher levels of malondialdehyde (MDA) in a dose-dependent manner when compared to the control. We concluded that nicotine as a pro-oxidant affects the oxidative state of the endometrial cells.

Oxidative stress on mitochondrial antioxidant defense system in the aging process: Role of dl-α-lipoic acid and l-carnitine

2005 ◽  
Vol 355 (1-2) ◽  
pp. 173-180 ◽  
Author(s):  
Sethumadhavan Savitha ◽  
Jayavelu Tamilselvan ◽  
Muthuswamy Anusuyadevi ◽  
Chinnakannu Panneerselvam
Keyword(s):  
Oxidative Stress ◽  
Lipoic Acid ◽  
Aging Process ◽  
Antioxidant Defense ◽  
Antioxidant Defense System ◽  
Defense System
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