scholarly journals A Polymorphism at the Translation Start Site of the Vitamin D Receptor Gene Is Associated with the Response to Anti-Osteoporotic Therapy in Postmenopausal Women from Southern Italy

2015 ◽  
Vol 16 (12) ◽  
pp. 5452-5466 ◽  
Author(s):  
Valeria Conti ◽  
Giusy Russomanno ◽  
Graziamaria Corbi ◽  
Giuseppe Toro ◽  
Vittorio Simeon ◽  
...  
Keyword(s):  
Vitamin D ◽  
Postmenopausal Women ◽  
Vitamin D Receptor ◽  
Southern Italy ◽  
Receptor Gene ◽  
Vitamin D Receptor Gene ◽  
Start Site ◽  
Translation Start Site ◽  
Translation Start

scholarly journals Difference in Height Associated with a Translation Start Site Polymorphism in the Vitamin D Receptor Gene1

1998 ◽  
Vol 44 (5) ◽  
pp. 628-632 ◽  
Author(s):  
Kanshi Minamitani ◽  
Yoshihito Takahashi ◽  
Masanori Minagawa ◽  
Toshiyuki Yasuda ◽  
Hiroo Niimi
Keyword(s):  
Vitamin D ◽  
Vitamin D Receptor ◽  
Start Site ◽  
Translation Start Site ◽  
Translation Start

scholarly journals The Relationship between Polymorphisms in the Vitamin D Receptor Gene and Bone Mineral Density in Postmenopausal Women

ISRN Genetics ◽  
2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Jose M. Moran ◽  
Francisco J. Rodriguez-Velasco ◽  
Raul Roncero-Martin ◽  
Purificación Rey-Sanchez ◽  
Mariana Martinez ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Vitamin D Receptor ◽  
Meta Analysis ◽  
Receptor Gene ◽  
Vitamin D Receptor Gene ◽  
Mineral Density ◽  
Gene Environment

The objective of this study was to identify, through a systematic review of the literature, Vitamin D receptor gene (VDR) polymorphisms related to osteoporosis and their effects on bone mineral density (BMD). The articles dated between January 2000 and December 2011 in the Scielo and PubMed databases were reviewed. A total of 23 articles that studied the association between the BsmI, ApaI, FokI, and TaqI polymorphisms and bone mineral density in postmenopausal women were selected. We found systematic studies/meta-analysis (level E-I) and case-control/cohort (level E-IV) studies. No definite conclusions can be made regarding the association of BsmI, ApaI, FokI, and TaqI polymorphisms with BMD among postmenopausal women. Larger and more rigorous analytical studies with consideration of gene-gene/environment interactions are needed to further dissect the mechanisms by which VDR alleles influence BMD.

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