scholarly journals Cys2/His2 Zinc-Finger Proteins in Transcriptional Regulation of Flower Development

2018 ◽  
Vol 19 (9) ◽  
pp. 2589 ◽  
Author(s):  
Tianqi Lyu ◽  
Jiashu Cao
Keyword(s):  
Transcriptional Regulation ◽  
Molecular Mechanism ◽  
Zinc Finger ◽  
Flower Development ◽  
Hormonal Regulation ◽  
Regulatory Networks ◽  
Floral Organ ◽  
Zinc Finger Proteins ◽  
Higher Plant ◽  
Flowering Induction

Flower development is the core of higher-plant ontogenesis and is controlled by complex gene regulatory networks. Cys2/His2 zinc-finger proteins (C2H2-ZFPs) constitute one of the largest transcription factor families and are highly involved in transcriptional regulation of flowering induction, floral organ morphogenesis, and pollen and pistil maturation. Nevertheless, the molecular mechanism of C2H2-ZFPs has been gradually revealed only in recent years. During flowering induction, C2H2-ZFPs can modify the chromatin of FLOWERING LOCUS C, thereby providing additional insights into the quantification of transcriptional regulation caused by chromatin regulation. C2H2-ZFPs are involved in cell division and proliferation in floral organ development and are associated with hormonal regulation, thereby revealing how a flower is partitioned into four developmentally distinct whorls. The studies reviewed in this work integrate the information from the endogenous, hormonal, and environmental regulation of flower development. The structure of C2H2-ZFPs determines their function as transcriptional regulators. The findings indicate that C2H2-ZFPs play a crucial role in flower development. In this review, we summarize the current understanding of the structure, expression, and function of C2H2-ZFPs and discuss their molecular mechanism in flower development.

KRAB zinc-finger proteins contribute to the evolution of gene regulatory networks

Nature ◽  
2017 ◽  
Vol 543 (7646) ◽  
pp. 550-554 ◽  
Author(s):  
Michaël Imbeault ◽  
Pierre-Yves Helleboid ◽  
Didier Trono
Keyword(s):  
Zinc Finger ◽  
Gene Regulatory Networks ◽  
Regulatory Networks ◽  
Zinc Finger Proteins ◽  
Gene Regulatory

scholarly journals The Roles of CCCH Zinc-Finger Proteins in Plant Abiotic Stress Tolerance

2021 ◽  
Vol 22 (15) ◽  
pp. 8327
Author(s):  
Guoliang Han ◽  
Ziqi Qiao ◽  
Yuxia Li ◽  
Chengfeng Wang ◽  
Baoshan Wang
Keyword(s):  
Transcriptional Regulation ◽  
Abiotic Stress ◽  
Stress Tolerance ◽  
Zinc Finger ◽  
Molecular Mechanisms ◽  
Zinc Finger Proteins ◽  
Structural Domain ◽  
Cold Temperatures ◽  
Ccch Zinc Finger ◽  
Post Transcriptional Regulation

Zinc-finger proteins, a superfamily of proteins with a typical structural domain that coordinates a zinc ion and binds nucleic acids, participate in the regulation of growth, development, and stress adaptation in plants. Most zinc fingers are C2H2-type or CCCC-type, named after the configuration of cysteine (C) and histidine (H); the less-common CCCH zinc-finger proteins are important in the regulation of plant stress responses. In this review, we introduce the domain structures, classification, and subcellular localization of CCCH zinc-finger proteins in plants and discuss their functions in transcriptional and post-transcriptional regulation via interactions with DNA, RNA, and other proteins. We describe the functions of CCCH zinc-finger proteins in plant development and tolerance to abiotic stresses such as salt, drought, flooding, cold temperatures and oxidative stress. Finally, we summarize the signal transduction pathways and regulatory networks of CCCH zinc-finger proteins in their responses to abiotic stress. CCCH zinc-finger proteins regulate the adaptation of plants to abiotic stress in various ways, but the specific molecular mechanisms need to be further explored, along with other mechanisms such as cytoplasm-to-nucleus shuttling and post-transcriptional regulation. Unraveling the molecular mechanisms by which CCCH zinc-finger proteins improve stress tolerance will facilitate the breeding and genetic engineering of crops with improved traits.

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