scholarly journals Multiple Comorbidity Profile of Psychiatric Disorders in Epilepsy

2021 ◽  
Vol 10 (18) ◽  
pp. 4104
Author(s):  
Agata M. Grzegorzewska ◽  
Mariusz S. Wiglusz ◽  
Jerzy Landowski ◽  
Katarzyna Jakuszkowiak-Wojten ◽  
Wiesław J. Cubała ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Anxiety Disorder ◽  
Depressive Disorder ◽  
Psychiatric Disorders ◽  
Depressive Disorders ◽  
Self Report ◽  
Major Depressive ◽  
Comorbid Anxiety ◽  
Axis I ◽  
Dsm Iv

The co-occurrence of psychiatric disorders in people with epilepsy (PWE) is not well documented or studied. Anxiety and depressive disorders are the most frequent comorbid disorders in PWE. In this paper, we characterized the rates of multiple psychiatric disorder comorbidity by reanalyzing data from a study sample of PWE. A total of 96 outpatient PWE completed the self-report symptom scale, and were diagnosed using the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR) Axis I disorders (SCID-I). For analyses, patients were assigned to a comprehensive diagnostic group of anxiety and depressive disorders. In order to determine comorbidity across psychiatric diagnoses for the DSM-IV categories, Pearson’s chi-squared test (χ2) was used. In the study sample, eight patients (8.3% of the study sample, n = 96) had comorbid major depressive disorder and anxiety disorder. When looking at comorbidity of each diagnosis separately, it was determined that 50% of individuals with an anxiety disorder had comorbid Major Depressive Disorder (MDD) and 38% patients with MDD had comorbid anxiety disorder. This finding encourages a more systematic reporting of psychiatric prevalence data in epilepsy, especially taking into account the high ratio of multiple comorbid anxiety and depressive disorders in PWE.

Current Comorbidity of Psychiatric Disorders Among DSM-IV Major Depressive Disorder Patients in Psychiatric Care in the Vantaa Depression Study

2002 ◽  
Vol 63 (2) ◽  
pp. 126-134 ◽  
Author(s):  
Tarja K. Melartin ◽  
Heikki J. Rytsala ◽  
Ulla S. Leskela ◽  
Paula S. Lestela-Mielonen ◽  
T. Petteri Sokero ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Psychiatric Disorders ◽  
Psychiatric Care ◽  
Major Depressive ◽  
Dsm Iv

Family history of psychiatric disorders and the outcome of psychiatric patients with DSM-IV major depressive disorder

2011 ◽  
Vol 131 (1-3) ◽  
pp. 251-259 ◽  
Author(s):  
K. Mikael Holma ◽  
Tarja K. Melartin ◽  
Irina A.K. Holma ◽  
Tiina Paunio ◽  
Erkki T. Isometsä
Keyword(s):  
Major Depressive Disorder ◽  
Family History ◽  
Depressive Disorder ◽  
Psychiatric Disorders ◽  
Psychiatric Patients ◽  
Major Depressive ◽  
History Of ◽  
Dsm Iv

scholarly journals Anxious and non-anxious major depressive disorder in the World Health Organization World Mental Health Surveys

2015 ◽  
Vol 24 (3) ◽  
pp. 210-226 ◽  
Author(s):  
R. C. Kessler ◽  
N. A. Sampson ◽  
P. Berglund ◽  
M. J. Gruber ◽  
A. Al-Hamzawi ◽  
...  
Keyword(s):  
Mental Health ◽  
Risk Factors ◽  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Anxiety Disorders ◽  
Risk Markers ◽  
Major Depressive ◽  
Comorbid Anxiety ◽  
World Mental Health ◽  
Dsm Iv

Background.To examine cross-national patterns and correlates of lifetime and 12-month comorbid DSM-IV anxiety disorders among people with lifetime and 12-month DSM-IV major depressive disorder (MDD).Method.Nationally or regionally representative epidemiological interviews were administered to 74 045 adults in 27 surveys across 24 countries in the WHO World Mental Health (WMH) Surveys. DSM-IV MDD, a wide range of comorbid DSM-IV anxiety disorders, and a number of correlates were assessed with the WHO Composite International Diagnostic Interview (CIDI).Results.45.7% of respondents with lifetime MDD (32.0–46.5% inter-quartile range (IQR) across surveys) had one of more lifetime anxiety disorders. A slightly higher proportion of respondents with 12-month MDD had lifetime anxiety disorders (51.7%, 37.8–54.0% IQR) and only slightly lower proportions of respondents with 12-month MDD had 12-month anxiety disorders (41.6%, 29.9–47.2% IQR). Two-thirds (68%) of respondents with lifetime comorbid anxiety disorders and MDD reported an earlier age-of-onset (AOO) of their first anxiety disorder than their MDD, while 13.5% reported an earlier AOO of MDD and the remaining 18.5% reported the same AOO of both disorders. Women and previously married people had consistently elevated rates of lifetime and 12-month MDD as well as comorbid anxiety disorders. Consistently higher proportions of respondents with 12-month anxious than non-anxious MDD reported severe role impairment (64.4 v. 46.0%; χ21 = 187.0, p < 0.001) and suicide ideation (19.5 v. 8.9%; χ21 = 71.6, p < 0.001). Significantly more respondents with 12-month anxious than non-anxious MDD received treatment for their depression in the 12 months before interview, but this difference was more pronounced in high-income countries (68.8 v. 45.4%; χ21 = 108.8, p < 0.001) than low/middle-income countries (30.3 v. 20.6%; χ21 = 11.7, p < 0.001).Conclusions.Patterns and correlates of comorbid DSM-IV anxiety disorders among people with DSM-IV MDD are similar across WMH countries. The narrow IQR of the proportion of respondents with temporally prior AOO of anxiety disorders than comorbid MDD (69.6–74.7%) is especially noteworthy. However, the fact that these proportions are not higher among respondents with 12-month than lifetime comorbidity means that temporal priority between lifetime anxiety disorders and MDD is not related to MDD persistence among people with anxious MDD. This, in turn, raises complex questions about the relative importance of temporally primary anxiety disorders as risk markers v. causal risk factors for subsequent MDD onset and persistence, including the possibility that anxiety disorders might primarily be risk markers for MDD onset and causal risk factors for MDD persistence.

scholarly journals Functional Impairment in Patients with Major Depressive Disorder and Comorbid Anxiety Disorder

2013 ◽  
Vol 58 (12) ◽  
pp. 679-686 ◽  
Author(s):  
Margalida Gili ◽  
Mauro García Toro ◽  
Silvia Armengol ◽  
Javier García-Campayo ◽  
Adoración Castro ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Anxiety Disorder ◽  
Depressive Disorder ◽  
Functional Impairment ◽  
Major Depressive ◽  
Comorbid Anxiety

Do characteristics of patients with major depressive disorder differ between primary and psychiatric care?

2007 ◽  
Vol 37 (6) ◽  
pp. 893-904 ◽  
Author(s):  
MARIA S. VUORILEHTO ◽  
TARJA K. MELARTIN ◽  
HEIKKI J. RYTSÄLÄ ◽  
ERKKI T. ISOMETSÄ
Keyword(s):  
Primary Care ◽  
Major Depressive Disorder ◽  
Personality Disorder ◽  
Depressive Disorder ◽  
Psychiatric Care ◽  
Major Depressive ◽  
Co Morbidity ◽  
Axis I ◽  
Dsm Iv ◽  
Treatment Settings

Background. Despite the need for rational allocation of resources and cooperation between different treatment settings, clinical differences in patients with major depressive disorder (MDD) between primary and psychiatric care remain obscure. We investigated these differences in representative patient populations from primary care versus secondary level psychiatric care in the city of Vantaa, Finland.Method. We compared MDD patients from primary care in the Vantaa Primary Care Depression Study (PC-VDS) (n=79) with psychiatric out-patients (n=223) and in-patients (n=46) in the Vantaa Depression Study (VDS). DSM-IV diagnoses were assigned by the Structured Clinical Interview for DSM-IV Axis I disorders (SCID-I in PC-VDS) or Schedules for Clinical Assessment in Neuropsychiatry (SCAN in VDS), and SCID-II interviews. Comparable information was collected on depression severity, Axis I and II co-morbidity, suicidal behaviour, preceding clinical course, and attitudes towards and pathways to treatment.Results. Prevalence of psychotic subtype and severity of depression were highest among in-patients, but otherwise few clinical differences between psychiatric and primary care patients were detected. Suicide attempts, alcohol dependence, and cluster A personality disorder were associated with treatment in psychiatric care, whereas cluster B personality disorder was associated with primary care treatment. Patients' choice of the initial point of contact for current depressive symptoms seemed to be independent of prior clinical history or attitude towards treatment.Conclusions. Severe, suicidal and psychotic depression cluster in psychiatric in-patient settings, as expected. However, MDD patients in primary care or psychiatric out-patient settings may not differ markedly in their clinical characteristics. This apparent blurring of boundaries between treatment settings calls for enhanced cooperation between settings, and clearer and more structured division of labour.

Some mental disorders are based on networks, others on latent variables

2010 ◽  
Vol 33 (2-3) ◽  
pp. 166-167 ◽  
Author(s):  
Don Ross
Keyword(s):  
Major Depressive Disorder ◽  
Anxiety Disorder ◽  
Mental Disorders ◽  
Depressive Disorder ◽  
Latent Variables ◽  
Latent Variable ◽  
Generalized Anxiety ◽  
Major Depressive ◽  
Axis I Disorders ◽  
Axis I

AbstractCramer et al. persuasively conceptualize major depressive disorder (MDD) and generalized anxiety disorder (GAD) as network disorders, rejecting latent variable accounts. But how does their radical picture generalize across the suite of mental and personality disorders? Addictions are Axis I disorders that may be better characterized by latent variables. Their comorbidity relationships could be captured by inserting them as nodes in a super-network of Axis I conditions.

Sign in / Sign up

Export Citation Format

Share Document