scholarly journals The Value of Residual Volume/Total Lung Capacity as an Indicator for Predicting Postoperative Lung Function in Non-Small Lung Cancer

2021 ◽  
Vol 10 (18) ◽  
pp. 4159
Author(s):  
Oh-Beom Kwon ◽  
Chang-Dong Yeo ◽  
Hwa-Young Lee ◽  
Hye-Seon Kang ◽  
Sung-Kyoung Kim ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Lung Function ◽  
Total Lung Capacity ◽  
Mediastinal Lymph Node ◽  
Residual Volume ◽  
Node Dissection ◽  
Lung Capacity ◽  
The Difference ◽  
Postoperative Fev1 ◽  
Postoperative Lung Function

Chronic obstructive pulmonary disease (COPD) is one of the most frequently occurring concomitant diseases in patients with non-small cell lung cancer (NSCLC). It is characterized by small airways and the hyperinflation of the lung. Patients with hyperinflated lung tend to have more reserved lung function than conventionally predicted after lung cancer surgery. The aim of this study was to identify other indicators in predicting postoperative lung function after lung resection for lung cancer. Patients with NSCLC who underwent curative lobectomy with mediastinal lymph node dissection from 2017 to 2019 were included. Predicted postoperative FEV1 (ppoFEV1) was calculated using the formula: preoperative FEV1 × (19 segments-the number of segments to be removed) ÷ 19. The difference between the measured postoperative FEV1 and ppoFEV1 was defined as an outcome. Patients were categorized into two groups: preserved FEV1 if the difference was positive and non-preserved FEV1, if otherwise. In total, 238 patients were included: 74 (31.1%) in the FEV1 non-preserved group and 164 (68.9%) in the FEV1 preserved group. The proportion of preoperative residual volume (RV)/total lung capacity (TLC) ≥ 40% in the FEV1 non-preserved group (21.4%) was lower than in the preserved group (36.1%) (p = 0.03). In logistic regression analysis, preoperative RV/TLC ≥ 40% was related to postoperative FEV1 preservation. (adjusted OR, 2.02, p = 0.041). Linear regression analysis suggested that preoperative RV/TLC was positively correlated with a significant difference. (p = 0.004) Preoperative RV/TLC ≥ 40% was an independent predictor of preserved lung function in patients undergoing curative lobectomy with mediastinal lymph node dissection. Preoperative RV/TLC is positively correlated with postoperative lung function.

Changes in lung, airway, and chest wall function in boys and girls between 8 and 12 yr

1984 ◽  
Vol 57 (2) ◽  
pp. 304-308 ◽  
Author(s):  
M. E. Hibbert ◽  
J. M. Couriel ◽  
L. I. Landau
Keyword(s):  
Chest Wall ◽  
School Children ◽  
Total Lung Capacity ◽  
Residual Volume ◽  
Wall Function ◽  
Lung Volumes ◽  
Lung Capacity ◽  
Maximum Expiratory Flow ◽  
Lower Maximum ◽  
The Difference

Maximum expiratory flows, maximum inspiratory and expiratory pressures, and lung volumes were measured in 248 8-yr-old and 215 12-yr-old healthy school children. Eight-year-old girls had smaller total lung capacity but higher volume-corrected expiratory flows than boys. Maximum expiratory flow and total lung capacity increased more in girls than in boys between 8 and 12 yr. Girls had a greater increase in residual volume (0.23 liter for girls, 0.16 liter for boys) as well as lower maximum expiratory and inspiratory pressures (P less than 0.001). Girls have smaller lung volumes than boys, so one would expect smaller airways in girls, but girls generate greater flows, indicating that their airways are possibly wider than those of boys. There is also evidence of unequal growth of the airways and air spaces between 8 and 12 yr. Chest wall development appears less in girls than boys and the difference becomes more marked at 12 yr.

scholarly journals Faal Paru Statis

2019 ◽  
Vol 2 (3) ◽  
pp. 91
Author(s):  
Arief Bakhtiar ◽  
Wirya Sastra Amran
Keyword(s):  
Lung Function ◽  
Functional Residual Capacity ◽  
Total Lung Capacity ◽  
Normal Lung ◽  
Residual Volume ◽  
Arterial Blood Gas ◽  
Lung Capacity ◽  
Arterial Blood ◽  
Normal Lung Function ◽  
Residual Capacity

Respiration or breathing is the body’s attempt to meet the needs of O2 in the metabolic process and emit CO2 as a result of intermediary metabolism by lung and respiratory organs together so that the resulting cardiovascular oxygen rich blood. Respiration has three phases: ventilation, diffusion, perfusion. The situation is said to somebody normal lung function if the work process of ventilation, diffusion, perfusion, and the relationship between ventilation to perfusion of the person is in a relaxed state resulted in the partial pressure of arterial blood gas (PaO2 and PaCO2) were normal. Examination of lung function has an important role in assessing a lung function. However, the thing to know that these checks are supporting and quite helpful in making a specific diagnosis. With spirometry examination can be known or determined all the static volume except residual volume and respiratory capacity than the capacity of residual volume that contains components such as total lung capacity and functional residual capacity. Functional residual capacity measured by special methods such as by using the inert gas helium (helium dilution test), N2 washout and bodyplethysmograph. Some static pulmonary function parameters can interpret any kind of disturbance in the lungs. In restrictive disorders in general decreased static lung volumes. While the obstruction interference parameters are quite significant, namely an increase in residual volume (RV), functional residual capacity (FRC) and the ratio of residual volume and total lung capacity (RV/TLC)

Measurement of lung emptying patterns during slow exhalations

1983 ◽  
Vol 55 (6) ◽  
pp. 1818-1824 ◽  
Author(s):  
W. R. Scott ◽  
H. D. Van Liew
Keyword(s):  
Concentration Profile ◽  
Large Volume ◽  
Sulfur Hexafluoride ◽  
Vital Capacity ◽  
Total Lung Capacity ◽  
Residual Volume ◽  
Maximal Volume ◽  
Lung Capacity ◽  
The Difference ◽  
Volume Difference

Five subjects slowly inhaled a 200-ml bolus of sulfur hexafluoride (SF6) from residual volume (RV) followed by an O2-Ar mixture to total lung capacity, then exhaled to RV, either slowly or as rapidly as possible. Larger amounts of SF6 and N2 were recovered in fast than in slow exhalations. We calculated the gas volumes of the apical and basal halves of the parenchymal mass as functions of exhaled volume during slow exhalations from 1) the difference between SF6 recovered in slow and fast exhalations and 2) an estimate of the apex-to-base concentration profile of SF6 in the lung after inspiration. The maximal volume difference, where the apex contained 600 ml more gas than the base, occurred when 70% of the vital capacity had been exhaled. The same calculation, but using N2 data, gave unrealistically large volume differences. Apparently SF6 delivered as a bolus results in an apex-to-base gradient that is large relative to intraregional gradients, but dilution of the resident N2 by a non-N2 gas results in sizable intraregional gradients.

Prediction of postoperative lung function in lung cancer patients using perfusion scintigraphy

2018 ◽  
Vol 60 (4) ◽  
pp. 488-495
Author(s):  
Ik Dong Yoo ◽  
Jooyeon Jamie Im ◽  
Yong-An Chung ◽  
Eun Kyung Choi ◽  
Jin Kyung Oh ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Lung Function ◽  
Cancer Patients ◽  
Lung Perfusion ◽  
Perfusion Scintigraphy ◽  
Lung Perfusion Scintigraphy ◽  
Lung Cancer Patients ◽  
The Mean ◽  
Postoperative Fev1 ◽  
Postoperative Lung Function

Background Predicting postoperative lung function is critical in lung cancer patients. Perfusion scintigraphy has been used to estimate postoperative function after lung resection. Purpose To evaluate the usefulness of the posterior oblique method in relation to other conventional processing methods for predicting postoperative lung function using lung perfusion scintigraphy. Material and Methods Fifty-five patients with non-small-cell lung cancer who underwent lobectomy were enrolled. Forced expiratory volume in 1 s (FEV1) values were obtained from preoperative and postoperative pulmonary function tests. After performing lung perfusion scintigraphy, predicted FEV1 values were calculated using the segment, conventional, posterior, and posterior oblique methods. Postoperative FEV1 values were compared with predicted FEV1 values. Results The mean value of the preoperative FEV1 was 2.29 L and that of the postoperative FEV1 was 1.89 L. The mean values of the predicted postoperative FEV1 values for the segment, conventional, posterior, and posterior oblique were 1.83 L, 1.94 L, 1.88 L, and 1.89 L, respectively. Between the observed and predicted FEV1 values, there was a strong correlation without significant difference except for conventional method. Bland–Altman analysis showed that segment and posterior methods underestimated the FEV1, whereas conventional and posterior oblique methods overestimated the FEV1. Conclusion Predictions with each processing method of lung perfusion scintigraphy showed nearly similar results to the actual postoperative lung function. The posterior oblique method of lung perfusion scintigraphy showed a very small difference to such an extent as to be equal to the observed FEV1, implying that this method may be applied for predicting postoperative lung function in lung cancer patients.

Experience With the Two-Windows Method for Mediastinal Lymph Node Dissection in Lung Cancer

1998 ◽  
Vol 65 (3) ◽  
pp. 800-802 ◽  
Author(s):  
Masayuki Iwasaki ◽  
Kichizo Kaga ◽  
Noboru Nishiumi ◽  
Fumio Maitani ◽  
Hiroshi Inoue
Keyword(s):  
Lung Cancer ◽  
Lymph Node ◽  
Lymph Node Dissection ◽  
Mediastinal Lymph Node ◽  
Mediastinal Lymph Node Dissection ◽  
Node Dissection

STUDIES OF RESPIRATORY PHYSIOLOGY IN CHILDREN

PEDIATRICS ◽  
1959 ◽  
Vol 24 (2) ◽  
pp. 181-193
Author(s):  
C. D. Cook ◽  
P. J. Helliesen ◽  
L. Kulczycki ◽  
H. Barrie ◽  
L. Friedlander ◽  
...  
Keyword(s):  
Tidal Volume ◽  
Respiratory Rate ◽  
Vital Capacity ◽  
Total Lung Capacity ◽  
Lung Compliance ◽  
Respiratory Physiology ◽  
Residual Volume ◽  
Lung Volumes ◽  
Lung Capacity ◽  
Residual Capacity

Tidal volume, respiratory rate and lung volumes have been measured in 64 patients with cystic fibrosis of the pancreas while lung compliance and resistance were measured in 42 of these. Serial studies of lung volumes were done in 43. Tidal volume was reduced and the respiratory rate increased only in the most severely ill patients. Excluding the three patients with lobectomies, residual volume and functional residual capacity were found to be significantly increased in 46 and 21%, respectively. These changes correlated well with the roentgenographic evaluation of emphysema. Vital capacity was significantly reduced in 34% while total lung capacity was, on the average, relatively unchanged. Seventy per cent of the 61 patients had a signficantly elevated RV/TLC ratio. Lung compliance was significantly reduced in only the most severely ill patients but resistance was significantly increased in 35% of the patients studied. The serial studies of lung volumes showed no consistent trends among the groups of patients in the period between studies. However, 10% of the surviving patients showed evidence of significant improvement while 15% deteriorated. [See Fig. 8. in Source Pdf.] Although there were individual discrepancies, there was a definite correlation between the clinical evaluation and tests of respiratory function, especially the changes in residual volume, the vital capacity, RV/ TLC ratio and the lung compliance and resistance.

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