Needleless Ablation of Osteoid Osteoma and Osteoblastoma: The Emergent Role of MRgFUS

Osteoblastoma (OB) and osteoid osteoma (OO) are benign bone-forming tumors, with nearly identical basic microscopic features. The main difference is dimension (OO has usually a nidus measuring <2 cm in diameter). In addition, OB is biologically more active than OO, with a tendency to grow in size. Historically, treatments have included surgical resection and analgesics, although invasiveness and poor tolerance have led to the current standard of care moving toward interventional radiology, where radiofrequency ablation (RFA) represents the most diffuse technique. Magnetic resonance-guided focused ultrasound surgery (MRgFUS) has recently emerged as another innovative alternative treatment, providing tumor ablation through a needleless and ionizing radiation-free modality. In addition, this technique has the ability to guarantee a very precise and controlled increase in temperature, delivering small amounts of energy that can accurately destroy only the lesion, avoiding healthy surrounding tissues. The present review focuses on MRgFUS as the less invasive, safe, effective, and durable treatment option for the management of osteoid osteoma and osteoblastoma, including a description of technical details, indications and outcomes.

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Magnetic resonance-guided focused Ultrasound surgery for treatment of osteoid osteoma: How do we do it?

Journal Of Cardiovascular, Neurovascular & Stroke ◽

10.32896/cvns.v3n1.159-162 ◽

2021 ◽

Vol 3 (1) ◽

pp. 159-162

Author(s):

Khariah Mat Nor ◽

Marlina Tanty Ramli Hamid ◽

Basri Johan Jeet Abdullah ◽

Vivek Ajit Singh

Keyword(s):

Magnetic Resonance ◽

Osteoid Osteoma ◽

Severe Pain ◽

Bone Pain ◽

Focused Ultrasound ◽

Joint Involvement ◽

Invasive Technique ◽

Appendicular Skeleton ◽

Ultrasound Surgery ◽

Focused Ultrasound Surgery

Magnetic Resonance-guided Focused Ultrasound Surgery (MRgFUS) is an increasingly popular non-invasive technique for treatment of severe pain produced by soft tissue, solid or bone tumours. MRgFUS used targeted thermal ablation technique to control moderate to severe pain. Osteoid osteoma is a small benign, highly vascular tumour, composed of osteoid and woven bone, most commonly affect the appendicular skeleton. Bony spine involvement can produce painful scoliosis, while intra-articular joint involvement can cause irreversible joint damage. Clinical presentation is local bone pain which typically worsen at night and with increased activity. Conventional standard treatment of osteoid osteoma is analgesic or surgical intervention. Under conservative medical treatment, the patient needs to be on long term analgesic, e.g. salicylates, where well-known reported complications include renal tubular acidosis and gastric ulcer. The standard surgical treatment is curettage. However, this carry the risk of bleeding, infection and tissue damage. Minimally invasive radiofrequency ablation (RFA) or cryoablation which are the current treatment of choice also carry the risk of tumour rupture and bleeding. We present a case of severe bone pain from benign bone tumor (osteoid osteoma), successfully treated with noninvasive Magnetic MRgFUS.

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