scholarly journals Preparation of Fe3O4@PDA@Au@GO Composite as SERS Substrate and Its Application in the Enrichment and Detection for Phenanthrene

Micromachines ◽  
2022 ◽  
Vol 13 (1) ◽  
pp. 128
Author(s):  
Junyu Liu ◽  
Yiwei Liu ◽  
Yida Cao ◽  
Shihua Sang ◽  
Liang Guan ◽  
...  
Keyword(s):  
Surface Enhanced Raman Spectroscopy ◽  
Raman Signal ◽  
Sers Substrate ◽  
Visible Absorption ◽  
Highly Active ◽  
Electromagnetic Enhancement ◽  
Surface Enhanced Raman ◽  
Active Substrate ◽  
Polycyclic Aromatic ◽  
Sers Active Substrate

In this study, highly active Fe3O4@PDA@Au@GO surface-enhanced Raman spectroscopy (SERS) active substrate was synthesized for application in the enrichment and detection of trace polycyclic aromatic hydrocarbons (PAHs) in the environment. The morphology and structure were characterized by transmission electron microscopy (TEM), energy-dispersive spectroscopy (EDS), X-ray diffraction (XRD) and UV–visible absorption spectrum (UV–vis spectra). The effect of each component of Fe3O4@PDA@Au@GO nanocomposites on SERS was explored, and it was found that gold nanoparticles (Au NPs) are crucial to enhance the Raman signal based on the electromagnetic enhancement mechanism, and apart from enriching the PAHs through π–π interaction, graphene oxide (GO) also generates strong chemical enhancement of Raman signals, and polydopamine (PDA) can prevent Au from shedding and agglomeration. The existence of Fe3O4 aided the quick separation of substrate from the solutions, which greatly simplified the detection procedure and facilitated the reuse of the substrate. The SERS active substrate was used to detect phenanthrene in aqueous solution with a detection limit of 10−7 g/L (5.6 × 10−10 mol/L), which is much lower than that of ordinary Raman, it is promising for application in the enrichment and detection of trace PAHs.

Self-assembled two-dimensional gold nanoparticle film for sensitive nontargeted analysis of food additives with surface-enhanced Raman spectroscopy

The Analyst ◽  
2018 ◽  
Vol 143 (10) ◽  
pp. 2363-2368 ◽  
Author(s):  
Yiping Wu ◽  
Wenfang Yu ◽  
Benhong Yang ◽  
Pan Li
Keyword(s):  
Self Assembly ◽  
Food Additives ◽  
High Sensitivity ◽  
Surface Enhanced Raman Spectroscopy ◽  
Assembly Strategy ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Active Substrate ◽  
Nanoparticle Film ◽  
Sers Active Substrate

CTAB-functionalized Au NP film as SERS active substrate prepared by the evaporation-driven self-assembly strategy demonstrated high sensitivity and reproducibility for the detection of different food additives.

scholarly journals Fabrication of Silver Nanodendrites on Copper for Detecting Rhodamine 6G in Chili Powder Using Surface-enhanced Raman Spectroscopy

2021 ◽  
Vol 31 (4) ◽  
Author(s):  
Quynh-Ngan Luong ◽  
Tran Cao Dao ◽  
Thi Thu Vu ◽  
Manh Cuong Nguyen ◽  
Nhu Duong Nguyen
Keyword(s):  
Raman Spectroscopy ◽  
Rhodamine 6G ◽  
Surface Enhanced Raman Spectroscopy ◽  
Sers Substrate ◽  
Simple Method ◽  
Sers Substrates ◽  
Highly Active ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Silver Nanodendrites

Surface-enhanced Raman spectroscopy (SERS) is increasingly being used as a method for detecting traces of contaminants in a variety of specimens. In order to maximize SERS’s performance, the most important thing is to have highly active SERS substrates. In this report, we present a simple method for synthesizing silver nanodendrites (AgNDs) on the surface of a copper (Cu) plate using chemical deposition method. The results showed that, after fabrication, a large number of fern-like AgNDs formed on the Cu surface. These AgNDs are distributed evenly across the entire Cu surface with a relatively thick density. The prepared AgNDs were applied as SERS substrates for detecting Rhodamine 6G (R6G) in chili powders. The results showed that, using the prepared AgNDs substrates, as low as 10−10 M R6G in chili powders can be detected. This demonstrates the applicability of fabricated AgNDs as a highly active SERS substrate.

scholarly journals Liquid Surface-Enhanced Raman Spectroscopy (SERS) Sensor-Based Au-Ag Colloidal Nanoparticles for Easy and Rapid Detection of Deltamethrin Pesticide in Brewed Tea

Crystals ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 24
Author(s):  
Affi Nur Hidayah ◽  
Djoko Triyono ◽  
Yuliati Herbani ◽  
Rosari Saleh
Keyword(s):  
Raman Spectroscopy ◽  
Liquid Surface ◽  
Limit Of Detection ◽  
Surface Enhanced Raman Spectroscopy ◽  
Ease Of Use ◽  
Raman Signal ◽  
Colloidal Nanoparticles ◽  
Sers Substrate ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

Deltamethrin pesticides can cause inflammation, nephrotoxicity and hepatotoxicity as well as affect the activity of antioxidant enzymes in tissues. As a result of this concern, there is a rising focus on the development of fast and reliable pesticide residue testing to minimise potential risks to humans. The goal of this study is to use Au-Ag colloid nanoparticles as liquid surface-enhanced Raman spectroscopy (SERS) to improve the Raman signal in the detection of deltamethrin pesticide in a brewed tea. The liquid SERS system is fascinating to study due to its ease of use and its unlikeliness to cause several phenomena, such as photo-bleaching, combustion, sublimation and even photo-catalysis, which can interfere with the Raman signal, as shown in the SERS substrate. Our liquid SERS system is simpler than previous liquid SERS systems that have been reported. We performed the detection of pesticide analyte directly on brewed tea, without diluting it with ethanol or centrifuging it. Femtosecond laser-induced photo-reduction was employed to synthesise the liquid SERS of Au, Au-Ag, and Ag colloidal nanoparticles. The SERS was utilised to detect deltamethrin pesticide in brewed tea. The result showed that liquid SERS-based Ag NPs significantly enhance the Raman signal of pesticides compared with liquid SERS-based Au NPs and Au-Ag Nanoalloys. The maximum residue limits (MRLs) in tea in Indonesia are set at 10 ppm. Therefore, this method was also utilised to detect and improve, to 0.01 ppm, the deltamethrin pesticide Limit of Detection (LOD).

scholarly journals Genetic Algorithm-Driven Surface-Enhanced Raman Spectroscopy Substrate Optimization

Nanomaterials ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 2905
Author(s):  
Buse Bilgin ◽  
Cenk Yanik ◽  
Hulya Torun ◽  
Mehmet Cengiz Onbasli
Keyword(s):  
Genetic Algorithm ◽  
Raman Spectroscopy ◽  
Strong Electric Field ◽  
Surface Enhanced Raman Spectroscopy ◽  
Raman Signal ◽  
Sers Substrate ◽  
Design Constraints ◽  
Sers Substrates ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

Surface-enhanced Raman spectroscopy (SERS) is a highly sensitive and molecule-specific detection technique that uses surface plasmon resonances to enhance Raman scattering from analytes. In SERS system design, the substrates must have minimal or no background at the incident laser wavelength and large Raman signal enhancement via plasmonic confinement and grating modes over large areas (i.e., squared millimeters). These requirements impose many competing design constraints that make exhaustive parametric computational optimization of SERS substrates prohibitively time consuming. Here, we demonstrate a genetic-algorithm (GA)-based optimization method for SERS substrates to achieve strong electric field localization over wide areas for reconfigurable and programmable photonic SERS sensors. We analyzed the GA parameters and tuned them for SERS substrate optimization in detail. We experimentally validated the model results by fabricating the predicted nanostructures using electron beam lithography. The experimental Raman spectrum signal enhancements of the optimized SERS substrates validated the model predictions and enabled the generation of a detailed Raman profile of methylene blue fluorescence dye. The GA and its optimization shown here could pave the way for photonic chips and components with arbitrary design constraints, wavelength bands, and performance targets.

scholarly journals Microfluidic setup for on-line SERS monitoring using laser induced nanoparticle spots as SERS active substrate

2017 ◽  
Vol 8 ◽  
pp. 237-243 ◽  
Author(s):  
Oana-M Buja ◽  
Ovidiu D Gordan ◽  
Nicolae Leopold ◽  
Andreas Morschhauser ◽  
Jörg Nestler ◽  
...  
Keyword(s):  
Sodium Citrate ◽  
Sers Substrate ◽  
Gold Chloride ◽  
Glass Capillary ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Active Substrate ◽  
On Line ◽  
Enhanced Raman Scattering ◽  
Sers Active Substrate

A microfluidic setup which enables on-line monitoring of residues of malachite green (MG) using surface-enhanced Raman scattering (SERS) is reported. The SERS active substrate was prepared via laser induced synthesis of silver or gold nanoparticles spot on the bottom of a 200 μm inner dimension glass capillary, by focusing the laser beam during a continuous flow of a mixture of silver nitrate or gold chloride and sodium citrate. The described microfluidic setup enables within a few minutes the monitoring of several processes: the synthesis of the SERS active spot, MG adsorption to the metal surface, detection of the analyte when saturation of the SERS signal is reached, and finally, the desorption of MG from the spot. Moreover, after MG complete desorption, the regeneration of the SERS active spot was achieved. The detection of MG was possible down to 10−7 M concentration with a good reproducibility when using silver or gold spots as SERS substrate.

Ag dendritic nanostructures for rapid detection of thiram based on surface-enhanced Raman scattering

RSC Advances ◽  
2015 ◽  
Vol 5 (86) ◽  
pp. 70553-70557 ◽  
Author(s):  
Qiang Wang ◽  
Dun Wu ◽  
Zhidong Chen
Keyword(s):  
Rapid Detection ◽  
Agricultural Products ◽  
Raman Signal ◽  
Surface Enhanced ◽  
Dendritic Nanostructures ◽  
Surface Enhanced Raman ◽  
Active Substrate ◽  
Enhanced Raman Scattering ◽  
Sers Active Substrate ◽  
Signal Readout

We have developed a SERS-active substrate based on Ag dendritic nanostructures for sensitive Raman signal readout and fingerprint identification of pesticide residues in agricultural products and environments.

Human Spermatozoa on Nanostrucutured Ag Deposited on GaAs Surface

2002 ◽  
Vol 735 ◽  
Author(s):  
Lucia G. Quagliano
Keyword(s):  
Structural Information ◽  
Surface Enhanced Raman Spectroscopy ◽  
Human Spermatozoa ◽  
Raman Signal ◽  
Ag Particles ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Active Substrate ◽  
Promising Application ◽  
Nanoscale Science

ABSTRACTMotivated by the SERS (Surface Enhanced Raman Spectroscopy) sensitivity to very small amounts of material we are interested in the application of the SERS technique for studying complex biological systems, such as cells.Using nanometer-sized Ag particles deposited on GaAs surfaces as SERS-active substrate we have observed an enhancement of Raman signal from human spermatozoa. We have obtained structural information on extremely small amounts of biomaterials and at the same time evidence that the bio-systems are preserved on the surface.In our opinion, this kind of SERS-active substrates with nanometer-sized Ag particles on semiconductors might have promising application in nanoscale science and technology. In fact bio-molecules, cells and processes of their interfacing with Si, GaAs, silver and gold and other inorganic substrates, form the basis of bio-electronics a new emerging field at the crossing of molecular biology and nano-electronics with numerous electronic and biotechnological applications.

scholarly journals Dual-enhancement and dual-tag design for SERS-based sandwich immunoassays: evaluation of a metal–metal effect in 3D architecture

2021 ◽  
Vol 189 (1) ◽  
Author(s):  
Ewelina Wiercigroch ◽  
Pawel Swit ◽  
Agnieszka Brzozka ◽  
Łukasz Pięta ◽  
Kamilla Malek
Keyword(s):  
Limit Of Detection ◽  
Specific Binding ◽  
3D Structure ◽  
Three Dimensional ◽  
Surface Enhanced Raman Spectroscopy ◽  
Raman Signal ◽  
Metal Metal ◽  
Surface Enhanced Raman ◽  
Active Substrate ◽  
Sandwich Type

Abstract The design of a sandwich-type SERS immunoassay (surface-enhanced Raman spectroscopy) is demonstrated operating in dual surface enhancement and dual-tag paradigm. The capture and detection antibodies are linked to two SERS-active substrates and form together the three-dimensional (3D) structure after specific binding to interleukin 6. A variety of metal combinations is tested (Au–Ag, Au–Au, and Ag–Ag), but an enhanced electromagnetic field is generated only due to coupling of Ag and Au nanoparticles with an Au hexagonal nanoarray. The amplified in that way Raman signals improve the limit of detection over 3 times in comparison to the assay with only one SERS-active substrate. It is also shown that the proper readout of the true-positive signal can be achieved in assays with two Raman tags, and this approach also improves LOD. For the optimal combination of the metal–metal junction and Raman tags, a linear relationship between the Raman signal and the concentration of IL-6 is obtained in the range 0–1000 pg⋅mL−1with LOD of 25.2 pg mL−1and RSD < 10%. The presented proof-of-concept of the SERS immunoassay with the dual-enhancement and dual-tag opens additional opportunities for engineering reliable SERS biosensing. Graphical abstract

scholarly journals Development and Application of Aptamer-Based Surface-Enhanced Raman Spectroscopy Sensors in Quantitative Analysis and Biotherapy

Sensors ◽  
2019 ◽  
Vol 19 (17) ◽  
pp. 3806 ◽  
Author(s):  
Hai-Xia Wang ◽  
Yu-Wen Zhao ◽  
Zheng Li ◽  
Bo-Shi Liu ◽  
Di Zhang
Keyword(s):  
Surface Enhanced Raman Spectroscopy ◽  
Raman Signal ◽  
Label Free ◽  
Sers Substrates ◽  
Highly Active ◽  
Detection Technology ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Sers Detection ◽  
Target Molecules

Surface-enhanced Raman scattering (SERS) is one of the most special and important Raman techniques. An apparent Raman signal can be observed when the target molecules are absorbed onto the surface of the SERS substrates, especially on the “hot spots” of the substrates. Early research focused on exploring the highly active SERS substrates and their detection applications in label-free SERS technology. However, it is a great challenge to use these label-free SERS sensors for detecting hydrophobic or non-polar molecules, especially in complex systems or at low concentrations. Therefore, antibodies, aptamers, and antimicrobial peptides have been used to effectively improve the target selectivity and meet the analysis requirements. Among these selective elements, aptamers are easy to use for synthesis and modifications, and their stability, affinity and specificity are extremely good; they have been successfully used in a variety of testing areas. The combination of SERS detection technology and aptamer recognition ability not only improved the selection accuracy of target molecules, but also improved the sensitivity of the analysis. Variations of aptamer-based SERS sensors have been developed and have achieved satisfactory results in the analysis of small molecules, pathogenic microorganism, mycotoxins, tumor marker and other functional molecules, as well as in successful photothermal therapy of tumors. Herein, we present the latest advances of the aptamer-based SERS sensors, as well as the assembling sensing platforms and the strategies for signal amplification. Furthermore, the existing problems and potential trends of the aptamer-based SERS sensors are discussed.

scholarly journals Preparation of ZnO nanoflowers for surface enhance Raman scattering applications

2020 ◽  
Vol 36 (1) ◽  
Author(s):  
Tuyen Nguyen Viet
Keyword(s):  
Raman Scattering ◽  
Self Assembly ◽  
Noble Metals ◽  
Zno Nanorods ◽  
Raman Signal ◽  
Sers Substrate ◽  
Chemical Substances ◽  
Sers Substrates ◽  
Electromagnetic Enhancement ◽  
Surface Enhanced Raman

Thanks to unique Raman spectra of chemical substances, a growing number of applications in environmental and biomedical fields based on Raman scattering has been developed. However, the low probability of Raman scattering hindered its potential development and thus, many different techniques were developed to enhance Raman signal. A key step of surface-enhanced Raman scattering technique is to prepare active SERS substrate from noble metals. The main enhancement mechanism is electromagnetic enhancement resulted from surface plasmon resonance. The disadvantages of nanoparticles based SERS substrates include high randomness due to self - assembly process of nanoparticles. Recently, a new kind of SERS substrates with order nanostructures of semiconductors combining with noble metals can serve as active SERS substrates, which are expected to possess high enhancement of Raman signals. In this study, ordered ZnO nanorods were first prepared by galvanic hydrothermal method and gold was sputtered on the as prepared ZnO nanomaterials to enhance Raman. Our SERS substrates exhibit promising high enhancement factors, and can detect chemical substances at concentration in nano molar range.

Sign in / Sign up

Export Citation Format

Share Document