scholarly journals Application of the Response Surface Methodology to Optimize the Fermentation Parameters for Enhanced Docosahexaenoic Acid (DHA) Production by Thraustochytrium sp. ATCC 26185

Molecules ◽  
2018 ◽  
Vol 23 (4) ◽  
pp. 974 ◽  
Author(s):  
Kang Wu ◽  
Lijian Ding ◽  
Peng Zhu ◽  
Shuang Li ◽  
Shan He
Keyword(s):  
Response Surface Methodology ◽  
Docosahexaenoic Acid ◽  
Response Surface ◽  
Dha Production ◽  
Fermentation Parameters

Optimization of fermentation parameters in phage production using response surface methodology

2012 ◽  
Vol 39 (10) ◽  
pp. 1515-1522 ◽  
Author(s):  
Sung-Hye H. Grieco ◽  
Ann Y. K. Wong ◽  
W. Scott Dunbar ◽  
Ross T. A. MacGillivray ◽  
Susan B. Curtis
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Phage Production ◽  
Fermentation Parameters ◽  
Optimization Of Fermentation

scholarly journals Production of β-Glucosidase from a Newly IsolatedAspergillusSpecies Using Response Surface Methodology

2011 ◽  
Vol 2011 ◽  
pp. 1-9 ◽  
Author(s):  
Pilanee Vaithanomsat ◽  
Molnapat Songpim ◽  
Taweesiri Malapant ◽  
Akihiko Kosugi ◽  
Warunee Thanapase ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Ammonium Sulfate ◽  
Yeast Extract ◽  
Culture Medium ◽  
Specific Activity ◽  
Ph Value ◽  
Sulfate Concentration ◽  
Extract Concentration ◽  
Fermentation Parameters

A newly isolated fungusAspergillus nigerSOI017 was shown to be a good producer of β-glucosidase from all isolated fungal strains. Fermentation condition (pH, cellobiose concentration, yeast extract concentration, and ammonium sulfate concentration) was optimized for producing the enzyme in shake flask cultures. Response surface methodology was used to investigate the effects of 4 fermentation parameters (yeast extract concentration, cellobiose concentration, ammonium sulfate concentration, and pH) on β-glucosidase enzyme production. Production of β-glucosidase was most sensitive to the culture medium, especially the nitrogen source yeast extract. The optimized medium for producing maximum β-glucosidase specific activity consisted of 0.275% yeast extract, 1.125% cellobiose, and 2.6% ammonium sulfate at a pH value of 3.

Sign in / Sign up

Export Citation Format

Share Document