Adherence to Mediterranean Diet, Malnutrition, Length of Stay and Mortality in Elderly Patients Hospitalized in Internal Medicine Wards

: This investigation aimed to explore the adherence to a Mediterranean Diet and its relationship with length of stay and in-hospital mortality, circulating interleukins, body composition, and frailty, in elderly patients hospitalized in internal medicine wards. Thus, a cross-sectional study in 194 acute hospitalized, community-dwelling elderly patients was performed. Adherence to a Mediterranean Diet was evaluated by the Italian Mediterranean Index (IMI). Length of stay, but not in-hospital mortality rate, was higher in patients with a low IMI score, as compared to subjects with high IMI score. Markers of systemic inflammation, as well as circulating interleukin-6 and tumor necrosis factor alpha, were higher in patients with a low IMI score, with respect to patients with high IMI score. Furthermore, patients with low IMI score had increased fat mass and reduced lean mass, together with a higher prevalence of frailty, as compared to those presenting with high IMI score. In a multivariate logistic regression model, an IMI score < 3 resulted as an independent predictor of longer length of stay. In conclusion, low adherence to a Mediterranean Diet in elderly patients hospitalized in internal medicine wards is associated with higher length of stay and related to unfavorable changes in circulating pro-inflammatory markers and body composition.

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Polypharmacy, length of hospital stay, and in-hospital mortality among elderly patients in internal medicine wards. The REPOSI study

European Journal of Clinical Pharmacology ◽

10.1007/s00228-010-0977-0 ◽

2011 ◽

Vol 67 (5) ◽

pp. 507-519 ◽

Cited By ~ 159

Author(s):

Alessandro Nobili ◽

◽

Giuseppe Licata ◽

Francesco Salerno ◽

Luca Pasina ◽

...

Keyword(s):

Internal Medicine ◽

Elderly Patients ◽

Hospital Mortality ◽

Hospital Stay ◽

Length Of Hospital Stay ◽

Internal Medicine Wards

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Correction to: Hyperglycemia at admission, comorbidities, and in-hospital mortality in elderly patients hospitalized in internal medicine wards: data from the RePoSI Registry

Acta Diabetologica ◽

10.1007/s00592-021-01749-z ◽

2021 ◽

Author(s):

Salvatore Corrao ◽

Alessandro Nobili ◽

Giuseppe Natoli ◽

Pier Mannuccio Mannucci ◽

Francesco Perticone ◽

...

Keyword(s):

Internal Medicine ◽

Elderly Patients ◽

Hospital Mortality ◽

Internal Medicine Wards

A correction to this paper has been published: https://doi.org/10.1007/s00592-021-01749-z

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Hyperglycemia at admission, comorbidities, and in-hospital mortality in elderly patients hospitalized in internal medicine wards: data from the RePoSI Registry

Acta Diabetologica ◽

10.1007/s00592-021-01716-8 ◽

2021 ◽

Author(s):

Salvatore Corrao ◽

Alessandro Nobili ◽

Giuseppe Natoli ◽

Pier Mannuccio Mannucci ◽

Francesco Perticone ◽

...

Keyword(s):

Internal Medicine ◽

Elderly Patients ◽

Hospital Mortality ◽

Barthel Index ◽

Rating Scale ◽

Depression Scale ◽

Cognitive Status ◽

Hospital Death ◽

Glycemia Level ◽

Male Sex

Abstract Aims The association between hyperglycemia at hospital admission and relevant short- and long-term outcomes in elderly population is known. We assessed the effects on mortality of hyperglycemia, disability, and multimorbidity at admission in internal medicine ward in patients aged ≥ 65 years. Methods Data were collected from an active register of 102 internal medicine and geriatric wards in Italy (RePoSi project). Patients were recruited during four index weeks of a year. Socio-demographic data, reason for hospitalization, diagnoses, treatment, severity and comorbidity indexes (Cumulative Illness rating Scale CIRS-SI and CIRS-CI), renal function, functional (Barthel Index), and cognitive status (Short Blessed Test) and mood disorders (Geriatric Depression Scale) were recorded. Mortality rates were assessed in hospital 3 and 12 months after discharge. Results Of the 4714 elderly patients hospitalized, 361 had a glycemia level ≥ 250 mg/dL at admission. Compared to subjects with lower glycemia level, patients with glycemia ≥ 250 mg/dL showed higher rates of male sex, smoke and class III obesity. These patients had a significantly lower Barthel Index (p = 0.0249), higher CIRS-SI and CIRS-CI scores (p = 0.0025 and p = 0.0013, respectively), and took more drugs. In-hospital mortality rate was 9.2% and 5.1% in subjects with glycemia ≥ 250 and < 250 mg/dL, respectively (p = 0.0010). Regression analysis showed a strong association between in-hospital death and glycemia ≥ 250 mg/dL (OR 2.07; [95% CI 1.34–3.19]), Barthel Index ≤ 40 (3.28[2.44–4.42]), CIRS-SI (1.87[1.27–2.77]), and male sex (1.54[1.16–2.03]). Conclusions The stronger predictors of in-hospital mortality for older patients admitted in general wards were glycemia level ≥ 250 mg/dL, Barthel Index ≤ 40, CIRS-SI, and male sex.

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