Dietary fiber intake and reduced risk of ovarian cancer: a meta-analysis

Objective To evaluate the associations between dietary fiber intake and ovarian cancer risk. Methods A literature survey was conducted by searching the PubMed, Web of Science, and Wanfang Med Online databases up to March 1st, 2018. The effect of dietary fiber intake on ovarian cancer risk was evaluated by calculating relative risks with 95% confidence intervals (95%CI) using Stata 12.0 software. Results A total of 17 articles with 149,177 participants including 7609 ovarian cancer patients were included in this analysis. The summarized relative risk for ovarian cancer in participants with the highest compared with the lowest fiber intake was 0.760 (95%CI=0.702–0.823), with no significant between-study heterogeneity ( I2=12.4%). Subgroup analysis according to study design demonstrated positive associations in both cohort studies and case-control studies. Moreover, the results were consistent among populations from America, Europe, and Asia. No publication bias was found by Egger’s test or funnel plots. Conclusion This meta-analysis concluded that a high intake of dietary fiber could significantly reduce the risk of ovarian cancer compared with a low fiber intake.

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Dietary fiber intake, depression, and anxiety: a systematic review and meta-analysis of epidemiologic studies

Nutritional Neuroscience ◽

10.1080/1028415x.2021.2020403 ◽

2022 ◽

pp. 1-19

Author(s):

Faezeh Saghafian ◽

Maryam Hajishafiee ◽

Parisa Rouhani ◽

Parvane Saneei

Keyword(s):

Systematic Review ◽

Dietary Fiber ◽

Meta Analysis ◽

Epidemiologic Studies ◽

Depression And Anxiety ◽

Fiber Intake ◽

Dietary Fiber Intake

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Dietary fiber intake and risk of breast cancer: a meta-analysis of prospective cohort studies

American Journal of Clinical Nutrition ◽

10.3945/ajcn.111.015578 ◽

2011 ◽

Vol 94 (3) ◽

pp. 900-905 ◽

Cited By ~ 42

Author(s):

J.-Y. Dong ◽

K. He ◽

P. Wang ◽

L.-Q. Qin

Keyword(s):

Breast Cancer ◽

Cohort Studies ◽

Dietary Fiber ◽

Prospective Cohort ◽

Meta Analysis ◽

Fiber Intake ◽

Prospective Cohort Studies ◽

Dietary Fiber Intake

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Dietary fiber intake and risks of proximal and distal colon cancers: A systematic review and meta-analysis.

Journal of Clinical Oncology ◽

10.1200/jco.2017.35.15_suppl.e15080 ◽

2017 ◽

Vol 35 (15_suppl) ◽

pp. e15080-e15080 ◽

Cited By ~ 3

Author(s):

Yu Ma ◽

Peilin Huang ◽

Mingyue Hu ◽

Sunkai Ling ◽

Yuan Li ◽

...

Keyword(s):

Systematic Review ◽

Colon Cancer ◽

Cohort Studies ◽

Dietary Fiber ◽

Meta Analysis ◽

Distal Colon ◽

Proximal Colon ◽

Fiber Intake ◽

Dietary Fiber Intake ◽

Colon Cancers

e15080 Background: Epidemiological studies have suggested that intake of dietary fiber is associated with decreased risk of colon cancer, however, these findings are inconsistent in that dietary fiber intake is differentially associated with risks of proximal colon and distal colon cancers. To address this, we conducted a systematic review and meta-analysis. Methods: Pubmed database were searched to identify relevant cohort studies up to December 2016 to examine the association between dietary fiber and risks of proximal colon and distal colon cancers, respectively. A random-effects model was used to compute summary risk estimates. Results: 11 prospective cohort studies were identified and included in the analysis. We observed that the risk of proximal colon cancer was 14% lower among the highest dietary fiber intake compared with the lowest intake (RR = 0.86, 95% confidence interval [CI] = 0.78 to 0.95). A similar result was also found for distal colon cancer (RR = 0.79, 95% CI = 0.71 to 0.87). Conclusions: In current analysis, we show that dietary fiber intake is associated inversely with risks of both proximal and distal colon cancers.

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