scholarly journals An Accessible Diagnostic Toolbox to Detect Bacterial Causes of Ovine and Caprine Abortion

Pathogens ◽  
2021 ◽  
Vol 10 (9) ◽  
pp. 1147
Author(s):  
René van den Brom ◽  
Inge Santman-Berends ◽  
Remco Dijkman ◽  
Piet Vellema ◽  
Reinie Dijkman ◽  
...  

Results of laboratory investigations of ovine and caprine cases of abortion in the lambing season 2015–2016 were analyzed, using pathology records of submissions to Royal GD (Deventer, the Netherlands) from January until and including April 2016, in comparison with the results of two accessible alternative techniques for sampling aborted lambs and kids, swabbing the fetal oropharynx and puncture of the fetal lung. Chlamydia abortus was the main cause of abortion in sheep as well as in goats. Other causes of abortion were Campylobacter spp., Listeria spp., Escherichia coli, and Yersinia enterocolitica. Ovine pathological submissions resulted more often in detecting an infectious agent compared to caprine submissions. For the three main bacterial causes of abortion, Campylobacter spp., Listeria spp., and Chlamydia spp., compared to results of the pathological examination, oropharynx mucus, and fetal lung puncture samples showed an observed agreement of 0.87 and 0.89, an expected agreement of 0.579 and 0.584, and a kappa value of 0.691 and 0.737 (95% CI: 0.561–0.82 and 0.614–0.859), respectively. The agreement between the results of the pathological examination and both fetal lung puncture and oropharynx mucus samples was classified as good. In conclusion, although a full step-wise post-mortem examination remains the most proper way of investigating small ruminant abortions, the easily accessible, low-threshold tools for practitioners and farmers as described in this paper not only provide reliable results compared to results of the post-mortem examination but also stimulates farmers and veterinarians to submit fetuses and placentas if necessary. Suggestions for further improvement of both alternatives have been summarized. Both alternatives could also be tailor-made for specific regions with their specific causes of abortion.


1997 ◽  
Vol 38 (3) ◽  
pp. 253-262
Author(s):  
A.-M. Dalin ◽  
K. Gidlund ◽  
L. Eliasson-Selling


2021 ◽  
Vol 10 (7) ◽  
pp. 1337
Author(s):  
Astrid Malézieux-Picard ◽  
Cecilia Ferrer Soler ◽  
David De Macedo Ferreira ◽  
Emilie Gaud-Luethi ◽  
Christine Serratrice ◽  
...  

Background: Mechanisms and causes of death in older patients with SARS-CoV-2 infection are still poorly understood. Methods: We conducted in a retrospective monocentric study, a clinical chart review and post-mortem examination of patients aged 75 years and older hospitalized in acute care and positive for SARS-CoV-2. Full body autopsy and correlation with clinical findings and suspected causes of death were done. Results: Autopsies were performed in 12 patients (median age 85 years; median of 4 comorbidities, mainly hypertension and cardiovascular disease). All cases showed exudative or proliferative phases of alveolar damage and/or a pattern of organizing pneumonia. Causes of death were concordant in 6 cases (50%), and undetected diagnoses were found in 6. Five patients died from hypoxemic respiratory failure due to coronavirus disease 2019 (COVID-19), five had another associated diagnosis and two died from alternative causes. Deaths that occurred in the second week were related to SARS-CoV-2 pneumonia whereas those occurring earlier were related mainly to heart failure and those occurring later to complications. Conclusions: Although COVID-19 hypoxemic respiratory failure was the most common cause of death, post-mortem pathological examination revealed that acute decompensation from chronic comorbidities during the first week of COVID-19 and complications in the third week contributed to mortality.



2018 ◽  
Vol 52 (1) ◽  
pp. 126-136 ◽  
Author(s):  
V. J. Strong ◽  
M. N. Sheppard ◽  
S. Redrobe ◽  
K. Baiker


2009 ◽  
Vol 29 (3) ◽  
pp. 225-228 ◽  
Author(s):  
A. E. P. Heazell ◽  
E. A. Martindale


1874 ◽  
Vol 20 (90) ◽  
pp. 259-262
Author(s):  
William T. Benham

Mary M., æt 14, was admitted into the Bristol Asylum July 15th, 1862. She is described in the case book as having a hydrocephalic cranium, measuring “24 inches in circumference, and 14 inches over vertex.” Trunk shortened and thickened; legs doubled up on the thighs, which were again slightly flexed on the abdomen. Quite unable to walk or stand, but could sit comfortably in a low chair. She possessed considerable intelligence; knew the name of the place from whence she came, and answered simple questions in a lively manner Had her bodily health and education have been well attended to, it is probable that she would have possessed a fair amount of mental power. She was dirty in her habits, but of a tractable disposition, and good tempered. During the year following her admission attempts were made to teach her to read, but without success; she, however, soon learnt to be cleanly in her person and habits.



1986 ◽  
Vol 15 (2) ◽  
pp. 95-98 ◽  
Author(s):  
P H Cooke ◽  
A E Goodship

An experiment was performed to determine the effects of stiffness of cruciate ligament prostheses upon joint function and degeneration. Twenty four sheep were allocated into four groups. One group had the ligament excised with no replacement and subsequent groups underwent substitution procedures with either a stiff, matched, or lax prosthesis. After six months the animals with a stiff or matched prosthesis were significantly less lame than those with a lax prosthesis or no prosthesis. However, at post mortem examination the animals with a stiff prosthesis or no prosthesis showed significantly more widespread cartilage damage than the matched or lax groups. The results indicate that either a stiff or matched prosthesis may restore functional activity, but that the stiff prosthesis may predispose to increased degenerative changes.



1985 ◽  
Vol 53 (1) ◽  
pp. 24-28
Author(s):  
S. M. Cordner


Author(s):  
Arnold T. Mahne ◽  
Driene Janse van Rensburg ◽  
Michael Hewetson

A 4-year-old Thoroughbred gelding underwent an explorative celiotomy for a suspected small intestinal obstruction. During surgery, an impacted diverticulum of the ileum was suspected, necessitating a jejunocaecostomy. The owner opted for euthanasia. On post-mortem examination and histopathology, a true diverticulum on the mesenteric side of the ileum, with ileal hypertrophy, was diagnosed.



2018 ◽  
Vol 164 (3) ◽  
pp. 225.1-225
Author(s):  
J Barratt ◽  
M Welch ◽  
C Wright

IntroductionThe use of Celox gauze has been established in military practice as an adjunct in the treatment of external haemorrhage. The future character of conflict means that casualties may take longer to reach definitive care. The aim of this study was to test whether Celox Rapid, a topical haemostatic dressing, would maintain haemostasis during extended use in a junctional haemorrhage model.MethodsAn anaesthetised swine underwent simultaneous bilateral femoral arteriotomies; after 30 s of free bleeding Celox Rapid gauze was applied to the wound and pressure was maintained for 1 min. Following inspection for re-bleeding the Celox gauze was covered with standard field dressings and checked for re-bleeding every hour until the 6 hours had elapsed or the animal deceased.ResultsThere was no evidence of re-bleeding at any point up to and including 6 hours. The animal was declared deceased shortly afterwards. Celox Rapid gauze maintained haemostasis in extended use in this limited single animal model. Post mortem examination revealed a stable clot at the site of the arteriotomy with no evidence of re-bleeding.ConclusionCelox Rapid was effective at achieving initial homeostasis and preventing re-bleeding in this limited study using a single anaesthetised swine. Its potential for use in situations where evacuation and definitive care may be delayed should be explored.



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