Hydroxylated Dimeric Naphthoquinones Increase the Generation of Reactive Oxygen Species, Induce Apoptosis of Acute Myeloid Leukemia Cells and Are Not Substrates of the Multidrug Resistance Proteins ABCB1 and ABCG2

Blockade of JAK2/STAT3 intensifies the anti-tumor activity of arsenic trioxide in acute myeloid leukemia cells: Novel synergistic mechanism via the mediation of reactive oxygen species

European Journal of Pharmacology ◽

10.1016/j.ejphar.2018.07.010 ◽

2018 ◽

Vol 834 ◽

pp. 65-76 ◽

Cited By ~ 12

Author(s):

Yashar Mesbahi ◽

Ali Zekri ◽

Seyed H. Ghaffari ◽

Parvaneh Sadat Tabatabaie ◽

Shahin Ahmadian ◽

...

Keyword(s):

Reactive Oxygen Species ◽

Acute Myeloid Leukemia ◽

Arsenic Trioxide ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Oxygen Species ◽

Synergistic Mechanism ◽

Anti Tumor Activity ◽

Reactive oxygen species activate differentiation gene transcription of acute myeloid leukemia cells via the JNK/c-JUN signaling pathway

Leukemia Research ◽

10.1016/j.leukres.2018.03.012 ◽

2018 ◽

Vol 68 ◽

pp. 112-119 ◽

Cited By ~ 9

Author(s):

Chung Fan Lam ◽

Hoi Ting Yeung ◽

Yuk Man Lam ◽

Ray Kit Ng

Keyword(s):

Reactive Oxygen Species ◽

Acute Myeloid Leukemia ◽

Signaling Pathway ◽

Gene Transcription ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Oxygen Species ◽

Differentiation Gene ◽

The role of reactive oxygen species in the differentiation of acute myeloid leukemia cells

Experimental Hematology ◽

10.1016/j.exphem.2016.06.191 ◽

2016 ◽

Vol 44 (9) ◽

pp. S91

Author(s):

Ray Kit Ng ◽

Chung Fan Lam ◽

Yuk Man Lam ◽

Hoi Ting Yeung

Keyword(s):

Reactive Oxygen Species ◽

Acute Myeloid Leukemia ◽

Myeloid Leukemia ◽

Reactive Oxygen ◽

Leukemia Cells ◽

Oxygen Species ◽

CD34+ acute myeloid leukemia cells with low levels of reactive oxygen species show increased expression of stemness genes and can be targeted by the BCL2 inhibitor venetoclax

Haematologica ◽

10.3324/haematol.2019.229997 ◽

2019 ◽

Vol 105 (8) ◽

pp. e399-e403

Author(s):

Katharina Mattes ◽

Mylène Gerritsen ◽

Hendrik Folkerts ◽

Marjan Geugien ◽

Fiona A. van den Heuvel ◽

...

Keyword(s):

Reactive Oxygen Species ◽

Acute Myeloid Leukemia ◽

Myeloid Leukemia ◽

Reactive Oxygen ◽

Leukemia Cells ◽

Oxygen Species ◽

Low Levels ◽

Vorinostat Induces Reactive Oxygen Species and DNA Damage in Acute Myeloid Leukemia Cells

PLoS ONE ◽

10.1371/journal.pone.0020987 ◽

2011 ◽

Vol 6 (6) ◽

pp. e20987 ◽

Cited By ~ 73

Author(s):

Luca A. Petruccelli ◽

Daphné Dupéré-Richer ◽

Filippa Pettersson ◽

Hélène Retrouvey ◽

Sophia Skoulikas ◽

...

Keyword(s):

Reactive Oxygen Species ◽

Dna Damage ◽

Acute Myeloid Leukemia ◽

Myeloid Leukemia ◽

Reactive Oxygen ◽

Leukemia Cells ◽

Oxygen Species ◽

Bortezomib activity and in vitro interactions with anthracyclines and cytarabine in acute myeloid leukemia cells are independent of multidrug resistance mechanisms and p53 status

Cancer Chemotherapy and Pharmacology ◽

10.1007/s00280-006-0367-6 ◽

2006 ◽

Vol 60 (2) ◽

pp. 245-255 ◽

Cited By ~ 53

Author(s):

Hans Minderman ◽

Yunfei Zhou ◽

Kieran L. O’Loughlin ◽

Maria R. Baer

Keyword(s):

Acute Myeloid Leukemia ◽

Multidrug Resistance ◽

Myeloid Leukemia ◽

Resistance Mechanisms ◽

Leukemia Cells ◽

P53 Status ◽

Acute Myeloid ◽

In Vitro Interactions

Synergistic effect of ginsenoside Rg3 with verapamil on the modulation of multidrug resistance in human acute myeloid leukemia cells

Oncology Letters ◽

10.3892/ol.2014.1826 ◽

2014 ◽

Vol 7 (4) ◽

pp. 1265-1269 ◽

Cited By ~ 11

Author(s):

SUNG SU KIM ◽

SIN SEONG ◽

SUNG YOUNG KIM

Keyword(s):

Acute Myeloid Leukemia ◽

Multidrug Resistance ◽

Synergistic Effect ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Ginsenoside Rg3 ◽

Human Acute Myeloid Leukemia ◽

P005 Prognostic significance of the different multidrug resistance proteins co-expression in acute myeloid leukemia

Leukemia Research ◽

10.1016/s0145-2126(07)70353-3 ◽

2007 ◽

Vol 31 ◽

pp. S67

Author(s):

O. Zakharov ◽

E. Rybalkina ◽

A. Stavrovskaya ◽

M. Volkova ◽

S. Klimuk ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Multidrug Resistance ◽

Myeloid Leukemia ◽

Prognostic Significance ◽

Multidrug Resistance Proteins ◽

Resistance Proteins ◽

The glutathione S-transferase inhibitor 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol overcomes the MDR1-P-glycoprotein and MRP1-mediated multidrug resistance in acute myeloid leukemia cells

Cancer Chemotherapy and Pharmacology ◽

10.1007/s00280-009-0960-6 ◽

2009 ◽

Vol 64 (2) ◽

pp. 419-424 ◽

Cited By ~ 21

Author(s):

Alessandro Ascione ◽

Maurizio Cianfriglia ◽

Maria Luisa Dupuis ◽

Alessandra Mallano ◽

Andrea Sau ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Multidrug Resistance ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Glutathione S Transferase ◽

P Glycoprotein ◽

Induction of Multidrug Resistance of Acute Myeloid Leukemia Cells by Cocultured Stromal Cells via Upregulation of the PI3K/Akt Signaling Pathway

Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics ◽

10.3727/096504016x14634208143021 ◽

2016 ◽

Vol 24 (4) ◽

pp. 215-223 ◽

Cited By ~ 8

Author(s):

Ping Chen ◽

Qing Jin ◽

Qiang Fu ◽

Peidong You ◽

Xi Jiang ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Multidrug Resistance ◽

Signaling Pathway ◽

Stromal Cells ◽

Myeloid Leukemia ◽

Akt Signaling ◽

Leukemia Cells ◽

Akt Signaling Pathway ◽