scholarly journals Lung Deposition of Surfactant Delivered via a Dedicated Laryngeal Mask Airway in Piglets

Pharmaceutics ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 1858
Author(s):  
Anders Nord ◽  
Doris Cunha-Goncalves ◽  
Rikard Linnér ◽  
Federico Bianco ◽  
Fabrizio Salomone ◽  
...  
Keyword(s):  
Laryngeal Mask Airway ◽  
Endotracheal Tube ◽  
Pressure Support ◽  
Positive Airway Pressure ◽  
Lung Surfactant ◽  
Standard Technique ◽  
Lung Deposition ◽  
Laryngeal Mask ◽  
Vocal Cords ◽  
Catheter Tip

It is unknown if the lung deposition of surfactant administered via a catheter placed through a laryngeal mask airway (LMA) is equivalent to that obtained by bolus instillation through an endotracheal tube. We compare the lung deposition of surfactant delivered via two types of LMA with the standard technique of endotracheal instillation. 25 newborn piglets on continuous positive airway pressure support (CPAP) were randomized into three groups: 1—LMA-camera (integrated camera and catheter channel; catheter tip below vocal cords), 2—LMA-standard (no camera, no channel; catheter tip above the glottis), 3—InSurE (Intubation, Surfactant administration, Extubation; catheter tip below end of endotracheal tube). All animals received 100 mg·kg−1 of poractant alfa mixed with 99mTechnetium-nanocolloid. Surfactant deposition was measured by gamma scintigraphy as a percentage of the administered dose. The median (range) total lung surfactant deposition was 68% (10–85), 41% (5–88), and 88% (67–92) in LMA-camera, LMA-standard, and InSurE, respectively, which was higher (p < 0.05) in the latter. The deposition in the stomach and nasopharynx was higher with the LMA-standard. The surfactant deposition via an LMA was lower than that obtained with InSurE. Although not statistically significant, introducing the catheter below the vocal cords under visual control with an integrated camera improved surfactant LMA delivery by 65%.

Resuscitation of Neonates with the Laryngeal Mask Airway—A Caution

PEDIATRICS ◽  
1995 ◽  
Vol 95 (3) ◽  
pp. 453-454
Author(s):  
Joe Brimacombe ◽  
D. Gandini
Keyword(s):  
Laryngeal Mask Airway ◽  
Airway Pressure ◽  
Positive Pressure Ventilation ◽  
Positive Airway Pressure ◽  
Neonatal Resuscitation ◽  
Standard Technique ◽  
Intermittent Positive Pressure Ventilation ◽  
Laryngeal Mask ◽  
Positive Pressure ◽  
Meconium Aspiration

We would like to report our experience with the laryngeal mask airway (LMA) for neonatal resuscitation. The LMA was used in neonates with apnea or heart rate &lt;100 min-1 who had no evidence of meconium aspiration. The LMA was inserted using the standard technique with the cuff fully deflated and then inflated with 2 to 5 mL air.1 It was then held in place manually and connected to a pediatric Mapleson F circuit. Intermittent positive-pressure ventilation or continuous positive airway pressure was administered until respiration was established.

scholarly journals A comparison of laryngeal mask airway-supreme and endotracheal tube use with respect to airway protection in patients undergoing septoplasty: a randomized, single-blind, controlled clinical trial

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Erol Karaaslan ◽  
Sedat Akbas ◽  
Ahmet Selim Ozkan ◽  
Cemil Colak ◽  
Zekine Begec
Keyword(s):  
Laryngeal Mask Airway ◽  
Adverse Events ◽  
Endotracheal Tube ◽  
Sore Throat ◽  
Fiberoptic Bronchoscopy ◽  
Laryngeal Mask ◽  
Controlled Clinical Trial ◽  
Airway Protection ◽  
Link Type ◽  
Single Blind

Abstract Background There are doubts among anesthesiologists on the use of the Laryngeal Mask Airway (LMA) in nasal surgeries because of concerns about the occurrence of blood leakages to the airway. We hypothesized that the use of LMA-Supreme (LMA-S) in nasal surgery is comparable with endotracheal tube (ETT) according to airway protection against blood leakage through the fiberoptic bronchoscopy, oropharyngeal leakage pressure (OLP), heart rate (HR), mean arterial pressure (MAP), and postoperative adverse events. Methods The present study was conducted in a prospective, randomized, single-blind, controlled manner on 80 patients, who underwent septoplasty procedures under general anesthesia, after dividing them randomly into two groups according to the device used (LMA-S or ETT). The presence of blood in the airway (glottis/trachea, distal trachea) was analyzed with the fiberoptic bronchoscope and a four-point scale. Both groups were evaluated for OLP; HR; MAP; postoperative sore throat, nausea, and vomiting; dysphagia; and dysphonia. Results In the fiberoptic evaluation of the airway postoperatively, less blood leakage was detected in both anatomic areas in the LMA-S group than in the ETT group (glottis/trachea, p = 0.004; distal trachea, p = 0.034). Sore throat was detected less frequently in the LMA-S group at a significant level in the 2nd, 6th, and 12th hours of postoperative period; however, other adverse events were similar in both groups. Hemodynamic parameters were not different between the two groups. Conclusion The present findings demonstrate that the LMA-S provided more effective airway protection than the ETT in preventing blood leakage in the septoplasty procedures. We believe that the LMA-S can be used safely and as an alternative to the ETT in septoplasty cases. Trial registration This trial is registered at the US National Institutes of Health (ClinicalTrials.gov) # NCT03903679 on April 5, 2019.

Laryngeal Mask Airway or Endotracheal Tube for Percutaneous Dilatational Tracheostomy

2010 ◽  
Vol 110 (4) ◽  
pp. 1076-1082 ◽  
Author(s):  
Ulf Linstedt ◽  
Michael Zenz ◽  
Kirsten Krull ◽  
Dietrich Häger ◽  
Andreas W. Prengel
Keyword(s):  
Laryngeal Mask Airway ◽  
Endotracheal Tube ◽  
Percutaneous Dilatational Tracheostomy ◽  
Laryngeal Mask ◽  
Dilatational Tracheostomy

scholarly journals Second-generation laryngeal mask airway as an alternative to endotracheal tube during prolonged laparoscopic abdominal surgery: a comparative analysis of intraoperative gas exchanges

2021 ◽  
Author(s):  
S Park ◽  
JE Lee ◽  
GS Choi ◽  
JM Kim ◽  
JS Ko ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Gas Exchange ◽  
Laryngeal Mask Airway ◽  
Abdominal Surgery ◽  
Partial Pressure ◽  
Endotracheal Tube ◽  
Second Generation ◽  
Laryngeal Mask ◽  
Arterial Partial Pressure ◽  
Prolonged Surgery

Introduction: Despite several advantages over endotracheal tube (ETT), laryngeal mask airway (LMA), which is used in emergencies under difficult airway maintenance conditions, is rarely utilized in prolonged surgery. We compared the variables representing intraoperative gas exchange with second-generation LMA and ETT during prolonged laparoscopic abdominal surgery. Methods: Prolonged surgery was defined as a surgery lasting more than 2 h. In total, 394 patients who underwent laparoscopic liver resection via either second-generation LMA or ETT were retrospectively analysed. Parameters including end-tidal pressure of carbon dioxide (ETCO2), tidal volume (TV), respiratory rate (RR), peak inspiratory pressure (PIP), arterial partial pressure of carbon dioxide (PaCO2), pH, and ratio of arterial partial pressure of oxygen to fractional inspired oxygen (PFR) during surgery were compared between the two groups. In addition, the incidence of postoperative pulmonary complications (PPC) including pulmonary aspiration was also compared. Results: The values of ETCO2, TV, RR and PIP during pneumoperitoneum were comparable between the two groups. Although PaCO2 at 2 h after induction was higher in patients with LMA (40.5 vs. 38.5 mmHg, p < 0.001), the pH and PFR values of the two groups were comparable. The incidence of PPC was not different. Conclusion: During prolonged laparoscopic abdominal surgery, the second-generation LMA facilitates adequate intraoperative gas exchange and represents an alternative to ETT.

Sign in / Sign up

Export Citation Format

Share Document