scholarly journals Rabies Surveillance Identifies Potential Risk Corridors and Enables Management Evaluation

Viruses ◽  
2019 ◽  
Vol 11 (11) ◽  
pp. 1006 ◽  
Author(s):  
Amy J. Davis ◽  
Kathleen M. Nelson ◽  
Jordona D. Kirby ◽  
Ryan Wallace ◽  
Xiaoyue Ma ◽  
...  

Intensive efforts are being made to eliminate the raccoon variant of rabies virus (RABV) from the eastern United States and Canada. The United States Department of Agriculture (USDA) Wildlife Services National Rabies Management Program has implemented enhanced rabies surveillance (ERS) to improve case detection across the extent of the raccoon oral rabies vaccination (ORV) management area. We evaluated ERS and public health surveillance data from 2006 to 2017 in three northeastern USA states using a dynamic occupancy modeling approach. Our objectives were to examine potential risk corridors for RABV incursion from the U.S. into Canada, evaluate the effectiveness of ORV management strategies, and identify surveillance gaps. ORV management has resulted in a decrease in RABV cases over time within vaccination zones (from occupancy ( ψ ¯ ) of 0.60 standard error (SE) = 0.03 in the spring of 2006 to ψ ¯ of 0.33 SE = 0.10 in the spring 2017). RABV cases also reduced in the enzootic area (from ψ ¯ of 0.60 SE = 0.03 in the spring of 2006 to ψ ¯ of 0.45 SE = 0.05 in the spring 2017). Although RABV occurrence was related to habitat type, greater impacts were associated with ORV and trap–vaccinate–release (TVR) campaigns, in addition to seasonal and yearly trends. Reductions in RABV occupancy were more pronounced in areas treated with Ontario Rabies Vaccine Bait (ONRAB) compared to RABORAL V-RG®. Our approach tracked changes in RABV occurrence across space and time, identified risk corridors for potential incursions into Canada, and highlighted surveillance gaps, while evaluating the impacts of management actions. Using this approach, we are able to provide guidance for future RABV management.

2020 ◽  
Author(s):  
Hossein Noorazar ◽  
Lee Kalcsits ◽  
Vincent P. Jones ◽  
Matthew S. Jones ◽  
Kirti Rajagopalan

AbstractWinter chill accumulation is critical for the productivity and profitability of perennial tree fruit production systems. Several studies have quantified the impacts of global warming on risks of insufficient chill accumulation in the warmer tree fruit and nut production regions of the United States (US), such as the Southeast and California, where these risks are currently prevalent. In this work, we focus on the Pacific Northwest US – the largest production area in the US for apples, pears and cherries – and quantify the potential risk of insufficient chill accumulation. Our results highlight large spatial variations in response within the PNW, with northern areas projected to have reduced risks and southern areas projected to have increased risks. In the southern areas, rather than chill accumulation in and of itself, it is the combination of reduced and delayed chill accumulation with likely advancement in spring phenology that lead to production risks. In spite of future reductions to chill accumulation, risks of insufficient chill accumulation seem limited for apple even with advancement of spring phenology. Under the extreme “no climate policy” RCP 8.5 climate projections, the production risks are significant for early blooming crops (e.g. cherries) and varieties with relatively high chill portions requirements (e.g. Sam cherries), necessitating planning for management strategies such as frost protection and chemical management of budbreak to address potential risks which have not historically been a concern in the region. Under less extreme warming outcomes, the PNW tree fruit production systems are likely to remain resilient. Given that the convergence of the fulfillment of chilling requirements and environmental conditions promoting budbreak is where potential risk to perennial tree fruit production exists, future work should focus on understanding, modelling and projecting responses within this convergence space. Additionally, given significant spatial differences across a relatively small geographic range, it is also critical to understand and model these dynamics at a local landscape resolution for regions such as the PNW that faced limited risk historically, but could be exposed to new risks under a warming climate.


Plant Disease ◽  
2012 ◽  
Vol 96 (8) ◽  
pp. 1216-1221 ◽  
Author(s):  
J. A. Kolmer ◽  
D. L. Long ◽  
M. E. Hughes

Collections of Puccinia triticina were obtained from rust-infected leaves provided by cooperators throughout the United States and from wheat fields and breeding plots by United States Department of Agriculture–Agricultural Research Service personnel and cooperators in the Great Plains, Ohio River Valley, southeastern states, Oregon, and Washington State in order to determine the virulence of the wheat leaf rust population in 2010. Single uredinial isolates (537 total) were derived from the collections and tested for virulence phenotype on 19 lines of ‘Thatcher’ wheat and a winter wheat line that are near-isogenic for 20 leaf rust resistance genes. In 2010, 38 virulence phenotypes were described in the United States. Virulence phenotypes MLDSD, TDBJG, and TCRKG were the three most common phenotypes. Phenotype MLDSD is virulent to Lr17 and Lr39/Lr41 and was widely distributed throughout the United States. Phenotype TDBJG is virulent to Lr24 and was found in both the soft red winter wheat and hard red winter wheat regions. Phenotype TCRKG is virulent to Lr11, Lr18, and Lr26 and was found mostly in the soft red winter wheat region in the eastern United States. Virulence to Lr21 was found for the first time in North America in isolates collected from spring wheat cultivars in North Dakota and Minnesota.


2009 ◽  
Vol 1193 ◽  
Author(s):  
Kurt D. Gerdes ◽  
Steven L. Ross

The year 2009 marks 20 years since the Environmental Management program was first established in the Department of Energy. At that time, nearly 50 years of nuclear activity had left a legacy that included nuclear waste and environmental contamination at more than 100 sites across the United States. The extent of the risk to our citizens and communities was unknown, and certainly many of the processes and technologies to reduce that risk had not yet been invented. Since then, the Department of Energy has closed 86 of 108 sites originally assigned to the program nationwide. The Department of Energy has packaged and safely stored the nation’s entire excess plutonium inventory. The Department has pioneered new technologies that have allowed progress in retrieving millions of liters of tank waste and safely disposing of tens of thousands of cubic meters of transuranic waste. In Fiscal years 2006 and 2007 alone, the Department of Energy demolished approximately 500 buildings (nuclear, radioactive, and industrial) as part of our decontamination and decommissioning projects. Finally, there have been great strides in restoring groundwater contaminated with radionuclides using innovative treatment systems. In August 2005, a rigorous project management system was instituted. This Department of Energy program was built on the principle of prioritizing risk reduction supported by our four guiding tenets of safety, performance, clean-up, and closure. The mission activities at our clean-up sites are targeted at our highest risk activities. In planning its environmental clean-up efforts and developing the budget for those activities, the Department seeks to focus on work that will produce the greatest environmental benefit and the largest amount of risk reduction.


2015 ◽  
Vol 81 (17) ◽  
pp. 5736-5742 ◽  
Author(s):  
Dylan P. G. Short ◽  
Mark Double ◽  
Donald L. Nuss ◽  
Cameron M. Stauder ◽  
William MacDonald ◽  
...  

ABSTRACTChestnut blight is a devastating disease ofCastaneaspp. Mycoviruses that reduce virulence (hypovirulence) of the causative agent,Cryphonectria parasitica, can be used to manage chestnut blight. However, vegetative incompatibility (vic) barriers that restrict anastomosis-mediated virus transmission hamper hypovirulence efficacy. In order to effectively determine the vegetative incompatibility genetic structure ofC. parasiticafield populations, we have designed PCR primer sets that selectively amplify and distinguish alleles for each of the six known diallelicC. parasiticavicgenetic loci. PCR assay results were validated using a panel of 64 European tester strains with genetically determinedvicgenotypes. Analysis of 116C. parasiticaisolates collected from five locations in the eastern United States revealed 39 uniquevicgenotypes and generally good agreement between PCR and tester strain coculturing assays in terms ofvicdiversity and genotyping. However, incongruences were observed for isolates from multiple locations and suggested that the coculturing assay can overestimate diversity at the six knownvicloci. The availability of molecular tools for rapid and precisevicgenotyping significantly improves the ability to predict and evaluate the efficacy of hypovirulence and related management strategies.


HortScience ◽  
2011 ◽  
Vol 46 (3) ◽  
pp. 343-344
Author(s):  
Jeff Olsen

In the mid-1980s, eastern filbert blight (EFB) fungus, Anisogramma anomala (Peck) E. Müller, was discovered in Oregon's main hazelnut-producing region and now is present throughout the hazelnut-producing area. Oregon State University's (OSU) Hazelnut Breeding Program responded by developing EFB-resistant cultivars, the first of which was released in 2005. The breeding program has also selected for other beneficial traits such as uniform early nut maturation, larger kernel size, and improved kernel quality. A 2008 OSU economic study on the costs of establishing and producing hazelnuts showed that the EFB-resistant cultivars enhanced economic viability of orchards, increasing cumulative cash flow during the 12-year establishment period by $12,243 per hectare. Several completely resistant cultivars have been released from the OSU Hazelnut Breeding program, all of which have ‘Gasaway’ as a resistance source, which transmits a dominant allele at a single locus that provides resistance to EFB. Additional EFB-resistant genotypes have also been identified from a diversity of origins that are being integrated into the OSU breeding program to produce new cultivars expressing multiple sources of genetic resistance. Interest in growing hazelnuts is increasing in other parts of the United States; for example, the Arbor Day Foundation began the Hazelnut Research Project in 1996 in Nebraska. A Hybrid Hazelnut Consortium was formed to join the leading hazelnut researchers in the United States. The Consortium's goal is to create a world-leading research and breeding program to develop hazelnuts as a widely adapted, high-yielding, and low-input sustainable crop that is competitive with annual crops for food, feed, or bioenergy. At Rutgers University, there has been a program of breeding and research for hazelnuts for the eastern United States since 1996. The program currently has ≈11,000 hazelnut seedlings undergoing evaluation. The Rutgers program is also looking for winter-hardy genotypes. They have been working closely with OSU to assess the response of OSU hazelnut selections that are resistant to EFB in Oregon when they are exposed to EFB isolates collected from across the eastern United States. This work has demonstrated the need for cultivars to express multiple sources of resistance and has prompted quarantine on importation of hazelnut plants into Oregon from other states where EFB strains may differ. Rutgers is also searching for new sources of resistance to EFB from seedling populations from Europe with the goal of integrating these sources into American germplasm. More effective Integrated Pest Management for EFB-susceptible hazelnut cultivars has been developed by OSU scientists. They recommend a management program that integrates scouting for and pruning infected tissue, fungicidal sprays, and the use of more resistant cultivars. Advances in hazelnut fertilizer management have included descriptions of patterns of nitrogen uptake, distribution, and use using isotopically labeled nitrogen.


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