scholarly journals Case Report and Genomic Characterization of a Novel Porcine Nodavirus in the United States

Viruses ◽  
2021 ◽  
Vol 13 (1) ◽  
pp. 73
Author(s):  
Chenghuai Yang ◽  
Leyi Wang ◽  
Kent Schwartz ◽  
Eric Burrough ◽  
Jennifer Groeltz-Thrush ◽  
...  
Keyword(s):  
United States ◽  
Genetic Characterization ◽  
The United States ◽  
Nucleotide Identity ◽  
Flock House Virus ◽  
The Family ◽  
Genomic Characterization ◽  
A New Species ◽  
Generation Sequencing

Nodaviruses are small bisegmented RNA viruses belonging to the family Nodaviridae. Nodaviruses have been identified in different hosts, including insects, fishes, shrimps, prawns, dogs, and bats. A novel porcine nodavirus was first identified in the United States by applying next-generation sequencing on brain tissues of pigs with neurological signs, including uncontrollable shaking. RNA1 of the porcine nodavirus had the highest nucleotide identity (51.1%) to the Flock House virus, whereas its RNA2 shared the highest nucleotide identity (48%) with the RNA2 segment of caninovirus (Canine nodavirus). Genetic characterization classified porcine nodavirus as a new species under the genus Alphanodavirus. Further studies are needed to understand the pathogenicity and clinical impacts of this virus.

scholarly journals A molecular epidemiological analysis of the incursion of the raccoon strain of rabies virus into Canada

2005 ◽  
Vol 134 (3) ◽  
pp. 534-547 ◽  
Author(s):  
S. A. NADIN-DAVIS ◽  
F. MULDOON ◽  
A. I. WANDELER
Keyword(s):  
United States ◽  
New Brunswick ◽  
Genetic Characterization ◽  
The United States ◽  
Epidemiological Analysis ◽  
Cross Border ◽  
P Gene ◽  
Canadian Provinces ◽  
Index Cases

Three physically separate incursions of the raccoon strain of rabies have entered Canada, two into eastern Ontario in 1999 and one into New Brunswick in 2000. The course of these epizootics is described. Phylogenetic analysis of the index cases from these two provinces with raccoon rabies viruses representative of this strain in the United States supported the independence of these incursions into Canada via cross-border transmission from the United States. Genetic characterization of 190 isolates from these two Canadian provinces over a 550-bp region of the variable central portion of the viral P gene distinguished 14 variants in Ontario and five in New Brunswick although in both regions the variant represented by the initial case was most commonly encountered. The quasi-species nature of the Ontario virus was analysed using isolates taken at different times during the main outbreak to examine whether viral variation was increasing with time as well as changing in nature. These data provide a framework for study of future incursions of this rabies strain into Canada.

scholarly journals Genomic characterization of Salmonella Cerro ST367, an emerging Salmonella subtype in cattle in the United States

BMC Genomics ◽  
2014 ◽  
Vol 15 (1) ◽  
pp. 427 ◽  
Author(s):  
Lorraine D Rodriguez-Rivera ◽  
Andrea I Moreno Switt ◽  
Lovorka Degoricija ◽  
Rixun Fang ◽  
Craig A Cummings ◽  
...  
Keyword(s):  
United States ◽  
The United States ◽  
Genomic Characterization

scholarly journals Genetic Characterization of H1N2 Influenza A Viruses Isolated from Pigs throughout the United States

2002 ◽  
Vol 40 (3) ◽  
pp. 1073-1079 ◽  
Author(s):  
A. I. Karasin ◽  
J. Landgraf ◽  
S. Swenson ◽  
G. Erickson ◽  
S. Goyal ◽  
...  
Keyword(s):  
United States ◽  
Influenza A ◽  
Genetic Characterization ◽  
The United States ◽  
Influenza A Viruses

scholarly journals Genomic characterization of Canine circovirus detected in a dog with intermittent hemorrhagic gastroenteritis in Brazil

2020 ◽  
Vol 50 (5) ◽  
Author(s):  
Taís Fukuta Cruz ◽  
Thiago Neves Batista ◽  
Ester Mariane Vieira ◽  
Luiz Marcos Frediani Portela ◽  
Amanda Mahnke Baccarin ◽  
...  
Keyword(s):  
Complete Genome ◽  
The United States ◽  
Diagnostic Tools ◽  
German Shepherd ◽  
German Shepherd Dog ◽  
History Of ◽  
Genomic Characterization ◽  
And Control ◽  
Generation Sequencing

ABSTRACT: Because Canine circovirus (CanineCV) is a new species of the genus Circovirus, several issues related to its epidemiology, pathogenesis and clinical disease remain unknown. Thus, this study aimed to perform the characterization of the first complete genome sequence of CanineCV detected in a dog with diarrhea in Brazil. A stool sample was collected of a ten-month-old female German Shepherd dog which had signs of intermittent hemorrhagic gastroenteritis, vomiting, and a history of eating raw pork. The complete CanineCV genome was sequenced by Next-Generation Sequencing. The sequence had 2,063 nucleotides, showed a typical genomic organization for circovirus, and was grouped with strain 214 described in the United States by phylogenetic analysis. One amino acid change was found in the replicase protein, and because of that it was considered unique to CanineCV. Therefore, the characterization of the complete genome of Brazilian CanineCV can be used in future studies of molecular epidemiology, pathogenesis and development of diagnostic tools for the prevention and control of this disease.

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