scholarly journals Decreased Fetal Movements: A Sign of Placental SARS-CoV-2 Infection with Perinatal Brain Injury

Viruses ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 2517
Author(s):  
Guillaume Favre ◽  
Sara Mazzetti ◽  
Carole Gengler ◽  
Claire Bertelli ◽  
Juliane Schneider ◽  
...  
Keyword(s):  
Brain Injury ◽  
Caesarean Section ◽  
Severe Acute Respiratory Syndrome ◽  
Vertical Transmission ◽  
Fetal Heart ◽  
Heart Rhythm ◽  
Emergency Caesarean Section ◽  
Perinatal Brain Injury ◽  
Postnatal Transmission ◽  
Fetal Movements

Neonatal COVID-19 is rare and mainly results from postnatal transmission. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), however, can infect the placenta and compromise its function. We present two cases of decreased fetal movements and abnormal fetal heart rhythm 5 days after mild maternal COVID-19, requiring emergency caesarean section at 29 + 3 and 32 + 1 weeks of gestation, and leading to brain injury. Placental examination revealed extensive and multifocal chronic intervillositis, with intense cytoplasmic positivity for SARS-CoV-2 spike antibody and SARS-CoV-2 detection by RT-qPCR. Vertical transmission was confirmed in one case, and both neonates developed extensive cystic peri-ventricular leukomalacia.

Absence of Wharton’s jelly

2020 ◽  
Vol 13 (11) ◽  
pp. e237222
Author(s):  
Sarah J Murphy ◽  
Nikita Deegan ◽  
Bobby D O'Leary ◽  
Peter McParland
Keyword(s):  
Caesarean Section ◽  
Histological Examination ◽  
Umbilical Cord ◽  
Emergency Caesarean Section ◽  
Wharton’S Jelly ◽  
Female Infant ◽  
Fetal Bradycardia ◽  
Wharton's Jelly ◽  
Emergency Caesarean ◽  
Fetal Movements

Wharton’s jelly is a specialised tissue which surrounds the vasculature within the fetal umbilical cord. We present the case of a 42-year-old woman who gave birth to a female infant via emergency caesarean section. At the time of delivery, absence of Wharton’s jelly was noted. This finding was confirmed by histological examination. Emergency caesarean section was necessitated due to a fetal bradycardia, and of note, the patient had presented twice prior to this with reduced fetal movements.

scholarly journals Intrapartum Electronic Fetal Heart Rate Monitoring and the Prevention of Perinatal Brain Injury

2006 ◽  
Vol 108 (3, Part 1) ◽  
pp. 656-666 ◽  
Author(s):  
Ernest M. Graham ◽  
Scott M. Petersen ◽  
Dana K. Christo ◽  
Harold E. Fox
Keyword(s):  
Heart Rate ◽  
Brain Injury ◽  
Fetal Heart Rate ◽  
Fetal Heart ◽  
Heart Rate Monitoring ◽  
Perinatal Brain Injury ◽  
Fetal Heart Rate Monitoring

scholarly journals Anesthetic management for emergency caesarean section and craniotomy together: an overview of the challenge

2020 ◽  
Vol 9 (4) ◽  
pp. 1717
Author(s):  
Nidhi Pathak ◽  
Misha Katyal
Keyword(s):  
Traumatic Brain Injury ◽  
Pregnant Woman ◽  
Brain Injury ◽  
Caesarean Section ◽  
Anesthetic Management ◽  
Skull Fracture ◽  
Fetal Distress ◽  
Anaesthetic Management ◽  
Emergency Caesarean Section ◽  
Brain Contusion

Traumatic brain injury in a pregnant woman is a challenge for anaesthesiologist, surgeon as well as paediatrician as it involves care and management of two lives together. We hereby discuss anaesthetic management of a 23 year old pregnant woman with extra axial bleed and brain contusion and skull fracture. Since the fetus was viable without signs of fetal distress, decision of doing caesarean section followed by craniotomy was taken and our patient was discharged a week later and the baby was handed over to attendant the next day.

scholarly journals Transmission of SARS-CoV-2 to premature twins from an asymptomatic mother

2020 ◽  
Vol 9 (1) ◽  
Author(s):  
Philippa Gaunt ◽  
Imran Ahmed ◽  
Ruppa Geethanath ◽  
Majd Abu-Harb ◽  
Chike Onwuneme
Keyword(s):  
Caesarean Section ◽  
Severe Acute Respiratory Syndrome ◽  
Vertical Transmission ◽  
Horizontal Transmission ◽  
Case Presentation ◽  
Positive Mother ◽  
Intrauterine Transmission

AbstractObjectivesThe incidence of vertically transmitted severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could be higher than published. We feel that cases of SARS-CoV-2 vertical transmission are under-reported.Case presentationWe report a case of SARS-CoV-2 in premature monochorionic monoamniotic twins born by caesarean section to an asymptomatic SARS-CoV-2 positive mother.ConclusionsThis case supports the potential for intrauterine transmission of SARS-CoV-2 as previously reported. The incidence of SARS-CoV-2 vertical transmission from reported cases is low; however this may be due to the difficulty disproving horizontal transmission or under-reporting of cases.

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