scholarly journals Human Exposure Risk Assessment Due to Heavy Metals in Groundwater by Pollution Index and Multivariate Statistical Methods: A Case Study from South Africa

Water ◽  
2017 ◽  
Vol 9 (4) ◽  
pp. 234 ◽  
Author(s):  
Vetrimurugan Elumalai ◽  
K. Brindha ◽  
Elango Lakshmanan
Author(s):  
Songtao Wang ◽  
Zongjun Gao ◽  
Yuqi Zhang ◽  
Hairui Zhang ◽  
Zhen Wu ◽  
...  

This study investigated the characteristics and sources of heavy metals in a soil–ginger system and assessed their health risks. To this end, 321 topsoil samples and eight soil samples from a soil profile, and 18 ginger samples with root–soil were collected from a ginger-planting area in the Jing River Basin. The average concentration of heavy metals in the topsoil followed the order: Cr > Zn > Pb > Ni > Cu > As > Cd > Hg. In the soil profile, at depths greater than 80 cm, the contents of Cr, Ni, and Zn tended to increase with depth, which may be related to the parent materials, whereas As and Cu contents showed little change. In contrast, Pb content decreased sharply from top to bottom, which may be attributable to external environmental and anthropogenic factors. Multivariate statistical analysis showed that Cr, Ni, Cu, Zn, and Cd contents in soil are affected by natural sources, Pb and As contents are significantly affected by human activities, and Hg content is affected by farmland irrigation. Combined results of the single pollution index (Pi), geo-accumulation index (Igeo), and potential ecological risk assessment (Ei and RI) suggest that soil in the study area is generally not polluted by heavy metals. In ginger, Zn content was the highest (2.36 mg/kg) and Hg content was the lowest (0.0015 mg/kg). Based on the bioconcentration factor, Cd and Zn have high potential for enrichment in ginger. With reference to the limit of heavy metals in tubers, Cr content in ginger exceeds the standard in the study area. Although Cr does not accumulate in ginger, Cr enrichment in soil significantly increases the risk of excessive Cr content in ginger.


2020 ◽  
Vol 201 ◽  
pp. 110833 ◽  
Author(s):  
Samantha Jiménez-Oyola ◽  
María-Jesús García-Martínez ◽  
Marcelo F. Ortega ◽  
David Bolonio ◽  
Clara Rodríguez ◽  
...  

2019 ◽  
Vol 19 (3) ◽  
pp. 206-214 ◽  
Author(s):  
Qinghua Wu ◽  
Jiri Patocka ◽  
Kamil Kuca

Beauvericin (BEA) is a cyclic hexadepsipeptide, which derives from Cordyceps cicadae. It is also produced by Fusarium species, which are parasitic to maize, wheat, rice and other important commodities. BEA increases ion permeability in biological membranes by forming a complex with essential cations, which may affect ionic homeostasis. Its ion-complexing capability allows BEA to transport alkaline earth metal and alkali metal ions across cell membranes. Importantly, increasing lines of evidence show that BEA has an anticancer effect and can be potentially used in cancer therapeutics. Normally, BEA performs the anticancer effect due to the induced cancer cell apoptosis via a reactive oxygen species-dependent pathway. Moreover, BEA increases the intracellular Ca2+ levels and subsequently regulates the activity of a series of signalling pathways including MAPK, JAK/STAT, and NF-κB, and finally causes cancer cell apoptosis. In vivo studies further show that BEA reduces tumour volumes and weights. BEA especially targets differentiated and invasive cancer types. Currently, the anticancer activity of BEA is a hot topic; however, there is no review article to discuss the anticancer activity of BEA. Therefore, in this review, we have mainly summarized the anticancer activity of BEA and thoroughly discussed its underlying mechanisms. In addition, the human exposure risk assessment of BEA is also discussed. We hope that this review will provide further information for understanding the anticancer mechanisms of BEA.


2014 ◽  
Vol 88 (11) ◽  
pp. 1915-1928 ◽  
Author(s):  
Zhonghong Wang ◽  
Qinghua Wu ◽  
Kamil Kuča ◽  
Vlastimil Dohnal ◽  
Zhihong Tian

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