Determination of the degree of degradation of specific impurity B contained in the substance of the drug «Lomustine» by high-resolution HPLC–MS/MS method
Keyword(s):
A high-resolution HPLC–MS/MS method was proposed for the study of solutions of standards of specific impurity B contained in the substance of the drug «Lomustine», which is included in the List of Vital Medicines. A characteristic degradation product of specific impurity B, the content and quantity of which is not regulated by the European Pharmacopoeia, has been found.
2020 ◽
Vol 191
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pp. 113490
1987 ◽
Vol 45
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pp. 260-261
1990 ◽
Vol 48
(1)
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pp. 68-69
Keyword(s):
1983 ◽
Vol 44
(C7)
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pp. C7-149-C7-168
2000 ◽
Vol 42
(5)
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pp. 757