scholarly journals Dietary intake to help prevent Covid-19 implications: The devil is in the detail

2021 ◽  
pp. 20-27
Author(s):  
Sana Noreen ◽  
Abdul Rehman ◽  
Rabia Kanwal ◽  
Saba Saleem ◽  
Ayesha Sadiqa ◽  
...  

One of the most frequent antecedents of mortality in world is coronavirus that proceeds multitude metabolic disorders and is consequence of damaged lungs that is ultimately caused by contagious infection and virus called coronavirus. It effects people of every age mostly dominating in child, aged, people who have already poor immune system and lungs related disorders. It has tremendous effects on body affecting physical, emotional, cognitive and intellectual abilities as well. It leads to various clinical moderate to severe complications including acute respiratory distress syndrome (ARDS), pneumonia, coughing up blood, persistent chest pain, fever, SOB (shortness of breath), coughing up sputum, chills, sore throat, respiratory sputum production (phlegm), loss of sense and smell, headache, muscle aches, rashes and diarrhea etc. One of the most imprudent factors examined in these patients is acute respiratory distress syndrome (ARDS) as well which refers to respiratory failure, a mechanism in which body is unable to respond normally sequentially results by high level of widespread inflammation in lungs. Penurious immune system which contributes to higher rate of mortality worldwide present strong association with COVID-19. Metabolic disturbances contribute to the development and progression of respiratory distress, as well as they have serious consequences in next stages of life that can have harmful effects on health. In this review we will discuss the pathophysiology as well as the signs and symptoms of COVID-19, the morbidities related to this disease and the treatment required controlling this disorder. Keywords: Covid-19, Diet, Health Benefits.

2017 ◽  
Vol 87 (1) ◽  
Author(s):  
Muhammad Ijaz ◽  
Muhammad Jaffar Khan ◽  
Jawad Khan ◽  
. Usama

<p>Clinical judgement and suspicion of influenza based on signs and symptoms of influenza-like illness and severe acute respiratory illness are critical for better patient outcome. Whether clinical characteristics of patients are associated with the development of acute respiratory distress syndrome and PCR positivity of samples was the aim of this study. We included all patients (n=37) presenting with influenza like illness (ILI) or severe acute respiratory illness (SARI) to a tertiary care hospital in northwest Pakistan during December 2015 until the end of January 2016. Each patient was assessed for signs and symptoms, clinical features, treatment, complications and outcome of ILI and SARI. Throat or nasopharyngeal swabs were obtained from 36 patient and analyzed for the presence of Influenza virus by quantitative PCR.<strong><em> </em></strong>Patients presenting with ILI or SARI were febrile (p&lt;0.001, one sample <em>t-</em>test), significantly tachypneic (p&lt;0.001) and had critically lower oxygen saturation (p&lt;0.001). Nasal congestion at presentation (p=0.006, chi-square test for association) and infiltrates on chest radiographs (p=0.025) were significantly associated with acute respiratory distress syndrome. Likelihood of the occurrence of ARDS was significantly increased with decrease in oxygen saturation (Odds ratio; 0.75, 95% CI; 0.46, 1.21, p=0.048) and marginally significantly increased in lower age (Odds ratio; 0.82, 95% CI; 0.58, 1.15, p=0.055) and higher white cell count (Odds ratio; 1.001, 95% CI; 0.99, 1.002, p=0.054). The presence of Influenza type A/H1N1pdm09 strains was confirmed in 7/11 patients. However no significant difference was observed in the clinical features and complications of PCR positive and negative patients. Clinical signs and symptoms of influenza-like illness or severe acute respiratory illness significantly predict the development of complications irrespective of the positivity or negativity of laboratory qPCR reports.</p>


2022 ◽  
Vol 71 (6) ◽  
pp. 2254-55
Author(s):  
Seema Shafiq ◽  
Asim Riaz

Dear Editor, It is indeed an honour for us to contribute towards the ongoing research regarding the latest contagion, Coronavirus disease (COVID-19) as caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) leading to global pandemic with variable clinical outcomes. COVID-19 positive individuals present with a variety of signs and symptoms as sore throat, cough, fever, dyspnoea, headache, myalgia, nausea, and vomiting whereas, some develop severe acute respiratory distress syndrome with a fatality rate of about 10%.1 Possible oral findings include xerostomia, hypogeusia, and chemosensory alterations. Common routes of transmission being person-to-person via direct sneeze, cough, and droplet inhalation or by contact through mucosa of eyes, nose and saliva.


2020 ◽  
Vol 49 (10) ◽  
pp. 418-421
Author(s):  
Christopher Werlein ◽  
Peter Braubach ◽  
Vincent Schmidt ◽  
Nicolas J. Dickgreber ◽  
Bruno Märkl ◽  
...  

ZUSAMMENFASSUNGDie aktuelle COVID-19-Pandemie verzeichnet mittlerweile über 18 Millionen Erkrankte und 680 000 Todesfälle weltweit. Für die hohe Variabilität sowohl der Schweregrade des klinischen Verlaufs als auch der Organmanifestationen fanden sich zunächst keine pathophysiologisch zufriedenstellenden Erklärungen. Bei schweren Krankheitsverläufen steht in der Regel eine pulmonale Symptomatik im Vordergrund, meist unter dem Bild eines „acute respiratory distress syndrome“ (ARDS). Darüber hinaus zeigen sich jedoch in unterschiedlicher Häufigkeit Organmanifestationen in Haut, Herz, Nieren, Gehirn und anderen viszeralen Organen, die v. a. durch eine Perfusionsstörung durch direkte oder indirekte Gefäßwandschädigung zu erklären sind. Daher wird COVID-19 als vaskuläre Multisystemerkrankung aufgefasst. Vor dem Hintergrund der multiplen Organmanifestationen sind klinisch-pathologische Obduktionen eine wichtige Grundlage der Entschlüsselung der Pathomechanismen von COVID-19 und auch ein Instrument zur Generierung und Hinterfragung innovativer Therapieansätze.


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