Faculty Opinions recommendation of Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex.

Author(s):  
Tom Rapoport
2002 ◽  
Vol 32 (4) ◽  
pp. 457-466 ◽  
Author(s):  
Alessandra Devoto ◽  
Manuela Nieto-Rostro ◽  
Daoxin Xie ◽  
Christine Ellis ◽  
Rebecca Harmston ◽  
...  

Author(s):  
Jiayan Xie ◽  
Yimei Jin ◽  
Guang Wang

AbstractAs the largest family of E3 ligases, the Skp1-cullin 1-F-box (SCF) E3 ligase complex is comprised of Cullins, Skp1 and F-box proteins. And the SCF E3 ubiquitin ligases play an important role in regulating critical cellular processes, which promote degradation of many cellular proteins, including signal transducers, cell cycle regulators, and transcription factors. We review the biological roles of the SCF ubiquitin-ligase complex in gametogenesis, oocyte-to-embryo transition, embryo development and the regulation for estrogen and progestin. We find that researches about the SCF ubiquitin-ligase complex at the beginning of life are not comprehensive, thus more in-depth researches will promote its eventual clinical application.


Oncogene ◽  
2001 ◽  
Vol 20 (36) ◽  
pp. 5067-5074 ◽  
Author(s):  
Steven C Clifford ◽  
Dewi Astuti ◽  
Laura Hooper ◽  
Patrick H Maxwell ◽  
Peter J Ratcliffe ◽  
...  

PLoS ONE ◽  
2015 ◽  
Vol 10 (6) ◽  
pp. e0130288 ◽  
Author(s):  
Daniela Salat ◽  
Anja Winkler ◽  
Henning Urlaub ◽  
Manfred Gessler

2019 ◽  
Vol 33 (S1) ◽  
Author(s):  
Muriel Desbois ◽  
Oliver Crawley ◽  
Paul R. Evans ◽  
Scott T. Baker ◽  
Ikuo Masuho ◽  
...  

2001 ◽  
Vol 286 (2) ◽  
pp. 357-364 ◽  
Author(s):  
Silvia N Bocca ◽  
Mariana Muzzopappa ◽  
Susana Silberstein ◽  
Pablo Wappner

2012 ◽  
Vol 35 (9) ◽  
pp. 1539-1545 ◽  
Author(s):  
Hitoshi Sasajima ◽  
Koji Nakagawa ◽  
Makoto Kashiwayanagi ◽  
Hideyoshi Yokosawa

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