Faculty Opinions recommendation of Short-chain fatty acids regulate the enteric neurons and control gastrointestinal motility in rats.

2010 ◽  
Author(s):  
Beverley Greenwood ◽  
Brandt Wiskur
Keyword(s):  
Fatty Acids ◽  
Gastrointestinal Motility ◽  
Short Chain Fatty Acids ◽  
Enteric Neurons ◽  
Short Chain ◽  
And Control ◽  
Chain Fatty Acids

Short-Chain Fatty Acids Regulate the Enteric Neurons and Control Gastrointestinal Motility in Rats

2010 ◽  
Vol 138 (5) ◽  
pp. 1772-1782.e4 ◽  
Author(s):  
Rodolphe Soret ◽  
Julien Chevalier ◽  
Pierre De Coppet ◽  
Guillaume Poupeau ◽  
Pascal Derkinderen ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Gastrointestinal Motility ◽  
Short Chain Fatty Acids ◽  
Enteric Neurons ◽  
Short Chain ◽  
And Control ◽  
Chain Fatty Acids

Inulin and isomalto-oligosaccharide alleviate constipation and improve reproductive performance by modulating motility-related hormones, short-chain fatty acids, and feces microflora in pregnant sows

2021 ◽  
Vol 99 (10) ◽  
Author(s):  
Xiaorong Yu ◽  
Chunsheng Fu ◽  
Zhenchuan Cui ◽  
Guangyong Chen ◽  
Yinglei Xu ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Dietary Fiber ◽  
Gastrointestinal Motility ◽  
Reproductive Performance ◽  
Basal Diet ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Control Group ◽  
Fecal Microflora ◽  
Chain Fatty Acids

Abstract Constipation in gestating and lactating sows is common and the inclusion of dietary fiber may help to alleviate this problem. We investigated the effects of inulin (INU) and isomalto-oligosaccharide (IMO), two sources of soluble dietary fiber, on gastrointestinal motility-related hormones, short-chain fatty acids (SCFA), fecal microflora, and reproductive performance in pregnant sows. On day 64 of gestation, 30 sows were randomly divided into three groups and fed as follows: a basal diet, a basal diet with 0.5% INU, and a basal diet with 0.5% IMO. We found that INU and IMO significantly modulated the levels of gastrointestinal motility-related hormones, as evidenced by an increase in substance P (P < 0.05), and a decrease in the vasoactive intestinal peptide concentrations (P < 0.05), indicating the capacity of INU and IMO to alleviate constipation. Furthermore, IMO enhanced the concentrations of acetic, propionic, isobutyric, butyric, isovaleric, and valeric acids in the feces (P < 0.05). High-throughput sequencing showed that IMO and INU increased the fecal microflora α- and β-diversity (P < 0.05). Methanobrevibacter was more abundant (P < 0.05), whereas the richness of Turicibacter was lower in the INU and IMO groups than in the control group (P < 0.05). In addition, IMO significantly increased litter size (P < 0.05). Overall, our findings indicate that INU and IMO can relieve constipation, optimize intestinal flora, and promote reproductive performance in pregnant sows.

scholarly journals Postnatal development of the myenteric glial network and its modulation by butyrate

2016 ◽  
Vol 310 (11) ◽  
pp. G941-G951 ◽  
Author(s):  
François Cossais ◽  
Tony Durand ◽  
Julien Chevalier ◽  
Marie Boudaud ◽  
Laetitia Kermarrec ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Short Chain Fatty Acids ◽  
Enteric Neurons ◽  
Short Chain ◽  
Postnatal Maturation ◽  
Enteric Glial Cells ◽  
Postnatal Evolution ◽  
Chain Fatty Acids

The postnatal period is crucial for the development of gastrointestinal (GI) functions. The enteric nervous system is a key regulator of GI functions, and increasing evidences indicate that 1) postnatal maturation of enteric neurons affect the development of GI functions, and 2) microbiota-derived short-chain fatty acids can be involved in this maturation. Although enteric glial cells (EGC) are central regulators of GI functions, the postnatal evolution of their phenotype remains poorly defined. We thus characterized the postnatal evolution of EGC phenotype in the colon of rat pups and studied the effect of short-chain fatty acids on their maturation. We showed an increased expression of the glial markers GFAP and S100β during the first postnatal week. As demonstrated by immunohistochemistry, a structured myenteric glial network was observed at 36 days in the rat colons. Butyrate inhibited EGC proliferation in vivo and in vitro but had no effect on glial marker expression. These results indicate that the EGC myenteric network continues to develop after birth, and luminal factors such as butyrate endogenously produced in the colon may affect this development.

Effects of Short-Chain Fatty Acids on Gastrointestinal Motility

1997 ◽  
Vol 32 (sup222) ◽  
pp. 58-61 ◽  
Author(s):  
C. Cherbut ◽  
A. C. Aubé ◽  
H. M. Blottière ◽  
J. P. Galmiche
Keyword(s):  
Fatty Acids ◽  
Gastrointestinal Motility ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Chain Fatty Acids

Effects of inulin and isomalto-oligosaccharide on diphenoxylate-induced constipation, gastrointestinal motility-related hormones, short-chain fatty acids, and the intestinal flora in rats

2020 ◽  
Vol 11 (10) ◽  
pp. 9216-9225
Author(s):  
Junhong Lan ◽  
Kangli Wang ◽  
Guangyong Chen ◽  
Guangtian Cao ◽  
Caimei Yang
Keyword(s):  
Fatty Acids ◽  
Gastrointestinal Motility ◽  
Intestinal Flora ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Intestinal Health ◽  
Chain Fatty Acids

The prebiotics inulin (INU) and isomalto-oligosaccharide (IMO) influence intestinal health and immunity, but their effects on constipation are not clearly established.

Effect of short-chain fatty acids on the ethylene pathway in embryonic axes of Cicer arietinum during germination

1994 ◽  
Vol 92 (4) ◽  
pp. 629-635 ◽  
Author(s):  
Mercedes Gallardo ◽  
Paloma Munoz De Rueda ◽  
Angel Jesus Matilla ◽  
Isabel Maria Sanchez-Calle
Keyword(s):  
Fatty Acids ◽  
Cicer Arietinum ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Embryonic Axes ◽  
Chain Fatty Acids

Short-Chain Fatty Acids Prevent Diabetic Nephropathy In Vivo and In Vitro

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 92-OR ◽  
Author(s):  
WEI HUANG ◽  
YONG XU ◽  
YOUHUA XU ◽  
LUPING ZHOU ◽  
CHENLIN GAO
Keyword(s):  
Fatty Acids ◽  
Diabetic Nephropathy ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Chain Fatty Acids
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