Faculty Opinions recommendation of Review article: the role of the perioperative period in recurrence after cancer surgery.

2010 ◽  
Author(s):  
André Boezaart ◽  
Andrea Toufexis Esch
Keyword(s):  
Perioperative Period ◽  
Review Article ◽  
Cancer Surgery ◽  
After Cancer

scholarly journals Inflammation-Based Scores: A New Method for Patient-Targeted Strategies and Improved Perioperative Outcome in Cancer Patients

2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
Dario Bugada ◽  
Massimo Allegri ◽  
Patricia Lavand'homme ◽  
Marc De Kock ◽  
Guido Fanelli
Keyword(s):  
Cancer Patients ◽  
Low Cost ◽  
Perioperative Period ◽  
Cancer Surgery ◽  
Prognostic Scores ◽  
Perioperative Outcome ◽  
After Cancer ◽  
Definition Of ◽  
Anti Inflammation

Systemic inflammatory response (SIR) has actually been shown as an important prognostic factor associated with lower postoperative survival in several types of cancer. Thus, the challenge for physicians is to find specific, low-cost, and highlyreliable inflammatory markers, clearly correlated with prognosis and able to preoperatively stratify patient’s risk. Inflammation is a promising target to improve perioperative outcome, and data show that anti-inflammation techniques have a great potential in the perioperative period of cancer surgery. Inflammation scores could be useful to stratify patients with a potential better response to anti-inflammation strategies. Furthermore, inflammation scores could prevent failure of clinical trials by a better definition of patients to be included in such trials; inflammation scoring could clarify the real role of different drugs and techniques on outcome after cancer surgery, defining if different therapies are required for different patients. The role of this review is to focus on the currently available scores, in order to clarify their rationale and to analyze the actual evidence and limits, providing physicians with an updated overview of the possible inflammation-based prognostic scores for cancer patients undergoing surgery.

The Role of the Perioperative Period in Recurrence After Cancer Surgery

2010 ◽  
Vol 110 (6) ◽  
pp. 1636-1643 ◽  
Author(s):  
Antje Gottschalk ◽  
Sonal Sharma ◽  
Justin Ford ◽  
Marcel E. Durieux ◽  
Mohamed Tiouririne
Keyword(s):  
Perioperative Period ◽  
Cancer Surgery ◽  
After Cancer

Socioeconomic Disparities In Mortality After Cancer Surgery: The Role Of Failure To Rescue

2011 ◽  
Vol 165 (2) ◽  
pp. 268
Author(s):  
A.A. Ghaferi ◽  
J.B. Dimick ◽  
N. J.O. Birkmeyer ◽  
J.D. Birkmeyer
Keyword(s):  
Cancer Surgery ◽  
Socioeconomic Disparities ◽  
Failure To Rescue ◽  
After Cancer

scholarly journals A Real-Time Mobile Intervention to Reduce Sedentary Behavior Before and After Cancer Surgery: Usability and Feasibility Study (Preprint)

2019 ◽  
Author(s):  
Carissa A Low ◽  
Michaela Danko ◽  
Krina C Durica ◽  
Abhineeth Reddy Kunta ◽  
Raghu Mulukutla ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Sedentary Behavior ◽  
Real Time ◽  
Perioperative Period ◽  
Cancer Surgery ◽  
System Usability Scale ◽  
Before And After ◽  
Mobile Intervention ◽  
After Cancer

BACKGROUND Sedentary behavior (SB) is common after cancer surgery and may negatively affect recovery and quality of life, but postoperative symptoms such as pain can be a significant barrier to patients achieving recommended physical activity levels. We conducted a single-arm pilot trial evaluating the usability and acceptability of a real-time mobile intervention that detects prolonged SB in the perioperative period and delivers prompts to walk that are tailored to daily self-reported symptom burden. OBJECTIVE The aim of this study is to develop and test a mobile technology-supported intervention to reduce SB before and after cancer surgery, and to evaluate the usability and feasibility of the intervention. METHODS A total of 15 patients scheduled for abdominal cancer surgery consented to the study, which involved using a Fitbit smartwatch with a companion smartphone app across the perioperative period (from a minimum of 2 weeks before surgery to 30 days postdischarge). Participants received prompts to walk after any SB that exceeded a prespecified threshold, which varied from day to day based on patient-reported symptom severity. Participants also completed weekly semistructured interviews to collect information on usability, acceptability, and experience using the app and smartphone; in addition, smartwatch logs were examined to assess participant study compliance. RESULTS Of eligible patients approached, 79% (15/19) agreed to participate. Attrition was low (1/15, 7%) and due to poor health and prolonged hospitalization. Participants rated (0-100) the smartphone and smartwatch apps as very easy (mean 92.3 and 93.2, respectively) and pleasant to use (mean 93.0 and 93.2, respectively). Overall satisfaction with the whole system was 89.9, and the mean System Usability Scale score was 83.8 out of 100. Overall compliance with symptom reporting was 51% (469/927 days), decreasing significantly from before surgery (264/364, 73%) to inpatient recovery (32/143, 22%) and postdischarge (173/420, 41%). Overall Fitbit compliance was 70% (653/927 days) but also declined from before surgery (330/364, 91%) to inpatient (51/143, 36%) and postdischarge (272/420, 65%). CONCLUSIONS Perioperative patients with cancer were willing to use a smartwatch- and smartphone-based real-time intervention to reduce SB, and they rated the apps as very easy and pleasant to use. Compliance with the intervention declined significantly after surgery. The effects of the intervention on postoperative activity patterns, recovery, and quality of life will be evaluated in an ongoing randomized trial.

scholarly journals Potential role of transforming growth factor‐beta 1/Smad signaling in secondary lymphedema after cancer surgery

2020 ◽  
Vol 111 (7) ◽  
pp. 2620-2634
Author(s):  
Masaki Sano ◽  
Satoshi Hirakawa ◽  
Minoru Suzuki ◽  
Jun‐ichi Sakabe ◽  
Mikako Ogawa ◽  
...  
Keyword(s):  
Growth Factor ◽  
Transforming Growth Factor Beta ◽  
Potential Role ◽  
Transforming Growth Factor ◽  
Cancer Surgery ◽  
Smad Signaling ◽  
Secondary Lymphedema ◽  
Growth Factor Beta ◽  
After Cancer

scholarly journals A Real-Time Mobile Intervention to Reduce Sedentary Behavior Before and After Cancer Surgery: Usability and Feasibility Study

10.2196/17292 ◽  
2020 ◽  
Vol 3 (1) ◽  
pp. e17292 ◽  
Author(s):  
Carissa A Low ◽  
Michaela Danko ◽  
Krina C Durica ◽  
Abhineeth Reddy Kunta ◽  
Raghu Mulukutla ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Sedentary Behavior ◽  
Real Time ◽  
Perioperative Period ◽  
Cancer Surgery ◽  
System Usability Scale ◽  
Before And After ◽  
Mobile Intervention ◽  
After Cancer

Background Sedentary behavior (SB) is common after cancer surgery and may negatively affect recovery and quality of life, but postoperative symptoms such as pain can be a significant barrier to patients achieving recommended physical activity levels. We conducted a single-arm pilot trial evaluating the usability and acceptability of a real-time mobile intervention that detects prolonged SB in the perioperative period and delivers prompts to walk that are tailored to daily self-reported symptom burden. Objective The aim of this study is to develop and test a mobile technology-supported intervention to reduce SB before and after cancer surgery, and to evaluate the usability and feasibility of the intervention. Methods A total of 15 patients scheduled for abdominal cancer surgery consented to the study, which involved using a Fitbit smartwatch with a companion smartphone app across the perioperative period (from a minimum of 2 weeks before surgery to 30 days postdischarge). Participants received prompts to walk after any SB that exceeded a prespecified threshold, which varied from day to day based on patient-reported symptom severity. Participants also completed weekly semistructured interviews to collect information on usability, acceptability, and experience using the app and smartphone; in addition, smartwatch logs were examined to assess participant study compliance. Results Of eligible patients approached, 79% (15/19) agreed to participate. Attrition was low (1/15, 7%) and due to poor health and prolonged hospitalization. Participants rated (0-100) the smartphone and smartwatch apps as very easy (mean 92.3 and 93.2, respectively) and pleasant to use (mean 93.0 and 93.2, respectively). Overall satisfaction with the whole system was 89.9, and the mean System Usability Scale score was 83.8 out of 100. Overall compliance with symptom reporting was 51% (469/927 days), decreasing significantly from before surgery (264/364, 73%) to inpatient recovery (32/143, 22%) and postdischarge (173/420, 41%). Overall Fitbit compliance was 70% (653/927 days) but also declined from before surgery (330/364, 91%) to inpatient (51/143, 36%) and postdischarge (272/420, 65%). Conclusions Perioperative patients with cancer were willing to use a smartwatch- and smartphone-based real-time intervention to reduce SB, and they rated the apps as very easy and pleasant to use. Compliance with the intervention declined significantly after surgery. The effects of the intervention on postoperative activity patterns, recovery, and quality of life will be evaluated in an ongoing randomized trial.

Population Control (Review Article)

1961 ◽  
Vol 1 (3) ◽  
pp. 89-98
Author(s):  
Karol J. Krotki
Keyword(s):  
Population Control ◽  
Review Article ◽  
Small Enterprise ◽  
Opportunity Costs ◽  
Relative Importance ◽  
Factual Information ◽  
Undue Influence ◽  
Clear Cut ◽  
Economic Considerations

Discussions about the role of small enterprise in economic development tend to remain inconclusive partly because of the difficulty of assessing the relative importance of economic and non-economic objectives and partly because of the dearth of factual information on which to base an economic calculus. It is probably true, moreover, that, because of a lack of general agreement as to the economic case for or against small enterprise, non-economic considerations, including some merely romantic attitudes toward smallness and bigness, tend to exert an undue influence on public policies. There may, of course, be no clear-cut economic case. And noneconomic considerations should and will inevitably weigh significantly in policy decisions. If, however, some of the economic questions could be settled by more and better knowledge, these decisions could more accurately reflect the opportunity costs of pursuing non-economic objectives.

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