Faculty Opinions recommendation of Estrogen receptor alpha mediates progestin-induced mammary tumor growth by interacting with progesterone receptors at the cyclin D1/MYC promoters.

Author(s):  
Ferdinando Auricchio ◽  
Antimo Migliaccio
2012 ◽  
Vol 72 (9) ◽  
pp. 2416-2427 ◽  
Author(s):  
Sebastián Giulianelli ◽  
José P. Vaqué ◽  
Rocío Soldati ◽  
Victoria Wargon ◽  
Silvia I. Vanzulli ◽  
...  

2002 ◽  
Vol 64 (5-6) ◽  
pp. 827-836 ◽  
Author(s):  
James Hulit ◽  
Richard.J Lee ◽  
Robert G Russell ◽  
Richard G Pestell

2019 ◽  
Vol 11 (1) ◽  
pp. 25-36
Author(s):  
Priscila Prais Carneiro ◽  
Bruna Vicente de Oliveira ◽  
Antonio Marcio Teodoro Cordeiro Silva

Purpose: To investigate the association between polymorphisms in the genes of estrogen receptor alpha, estrogen receptor beta, and progesterone receptor and the genesis of endometriosis. Methods: Systematic review and meta-analysis of articles published fully in the PubMed database, in Portuguese, English, or Spanish, from 2006 to 2017, using the descriptors: “endometriosis,” “polymorphism,” “ESR1,” “ESR2,” “PROGINS,” “rs9340799,” “rs4986938,” and “rs1042838.” Results: A total of 20 studies were included based on the criterion of search for susceptibility to endometriosis related to polymorphisms of estrogen receptor alpha, estrogen receptor beta, and progesterone receptor genes. Analysis of all polymorphisms found no association with endometriosis. Conclusion: This meta-analysis showed that estrogen receptor alpha, estrogen receptor beta, and progesterone receptor polymorphisms are not related to susceptibility to endometriosis. However, such results may be able to provide more detailed interpretations of how they influence the pathogenesis of endometriosis.


Cell Reports ◽  
2016 ◽  
Vol 17 (1) ◽  
pp. 249-260 ◽  
Author(s):  
Obi L. Griffith ◽  
Szeman Ruby Chan ◽  
Malachi Griffith ◽  
Kilannin Krysiak ◽  
Zachary L. Skidmore ◽  
...  

2002 ◽  
Vol 39 (6) ◽  
pp. 739-743 ◽  
Author(s):  
J. Martín de las Mulas ◽  
J. Ordás ◽  
M. Y. Millán ◽  
A. Espinosa de los Monteros ◽  
C. Reymundo

Spontaneous basaloid adenomas occurred in four out of 354 dogs with mammary tumors. Affected dogs were pure-bred, intact females between 6 and 8 years of age. Three dogs were nuliparous, two had pseudopregnancies, and none had received contraceptive steroids. The tumors were multiple (three cases) or unique, less than 1 cm in diameter, well delineated, and composed of uniform cords and clusters of monomorphic epithelial cells with focal signs of squamous or glandular differentiation. A basal cell immunophenotype (cytokeratins 5 and 14 positive) without either glandular epithelial (cytokeratins 8, 18, and 19 negative) or myoepithelial (calponin negative) differentiation was observed in the majority of tumor cells. No recurrence or metastasis was recorded after follow-up periods between 3 and 24 months. In spite of the hormone-dependent nature of this tumor in female Beagles given experimental contraceptive steroids, spontaneous basaloid adenomas lacked estrogen receptor alpha and progesterone receptors.


Endocrine ◽  
2009 ◽  
Vol 35 (3) ◽  
pp. 459-466 ◽  
Author(s):  
Gisele Branchini ◽  
Lolita Schneider ◽  
Rodrigo Cericatto ◽  
Edison Capp ◽  
Ilma Simoni Brum

Sign in / Sign up

Export Citation Format

Share Document