Faculty Opinions recommendation of The effect of dual-chamber closed-loop stimulation on syncope recurrence in healthy patients with tilt-induced vasovagal cardioinhibitory syncope: a prospective, randomised, single-blind, crossover study.

2013 ◽  
Author(s):  
Paolo Della Bella ◽  
Pasquale Vergara
Keyword(s):  
Crossover Study ◽  
Closed Loop ◽  
Dual Chamber ◽  
Single Blind ◽  
Blind Crossover Study ◽  
Closed Loop Stimulation

scholarly journals Treating primary hypothyroidism with weekly doses of levothyroxine: a randomized, single-blind, crossover study

2012 ◽  
Vol 56 (4) ◽  
pp. 250-258 ◽  
Author(s):  
Andressa Bornschein ◽  
Gilberto Paz-Filho ◽  
Hans Graf ◽  
Gisah A. de Carvalho
Keyword(s):  
Crossover Study ◽  
Primary Hypothyroidism ◽  
Weekly Dose ◽  
Safe Alternative ◽  
Cardiac Symptoms ◽  
Daily Schedule ◽  
Single Blind ◽  
Levothyroxine Treatment ◽  
Randomized Crossover Study ◽  
Blind Crossover Study

OBJECTIVE: Compliance to levothyroxine treatment in hypothyroidism is compromised by daily schedule, and a weekly dose may be an alternative. SUBJECTS AND METHODS: This was a randomized, crossover study. Fourteen females were assigned to daily or weekly doses of LT4. After six weeks, they switched regimens. Thyroid parameters were measured at baseline, and after 42 and 84 days. Echocardiogram and hyperthyroidism symptoms were evaluated before and four hours after LT4 intake. RESULTS: In the weekly dose treatment, fT4 levels were higher after taking LT4, and lower seven days after the last dose; by the 6th week there was a small decrease in T3 levels. TSH remained unchanged and there were no hyperthyroidism symptoms or echocardiographic manifestations. CONCLUSION: Weekly dose leads to transient increases in fT4, without hyperthyroidism or cardiac symptoms. That approach seems to be a safe alternative for the treatment of hypothyroidism.

scholarly journals Acute effects of beer on endothelial function and hemodynamics: A single-blind, crossover study in healthy volunteers

Nutrition ◽  
2013 ◽  
Vol 29 (9) ◽  
pp. 1122-1126 ◽  
Author(s):  
Kalliopi Karatzi ◽  
Victoria G. Rontoyanni ◽  
Athanase D. Protogerou ◽  
Aggeliki Georgoulia ◽  
Konstantinos Xenos ◽  
...  
Keyword(s):  
Endothelial Function ◽  
Crossover Study ◽  
Healthy Volunteers ◽  
Acute Effects ◽  
Single Blind ◽  
Blind Crossover Study

A Trial of Fortagesic and Paramol 118 in Osteoarthritis

1976 ◽  
Vol 4 (6) ◽  
pp. 432-434 ◽  
Author(s):  
C J Andrews ◽  
L Cohen ◽  
R B Crail ◽  
G Douch ◽  
M G Sheldon ◽  
...  
Keyword(s):  
Side Effects ◽  
Crossover Study ◽  
Moderate Pain ◽  
Single Blind ◽  
Blind Crossover Study

Fortagesic was compared with Paramol 118 in a fourteen day single-blind crossover study in patients with moderate pain due to osteoarthritis. Both preparations were shown to be similarly effective. More side-effects were seen with Paramol 118 than with Fortagesic and more patients preferred Fortagesic. These differences were not statistically significant, but it is concluded that Fortagesic is a useful effective analgesic for standard use in moderate pain.

A Comparative Study of the Effectiveness and Safety of Two Non-Steroidal Anti-Inflammatory Agents, Nabumetone and Naproxen in Rheumatoid Arthritis

1982 ◽  
Vol 10 (4) ◽  
pp. 204-208 ◽  
Author(s):  
G Fostiropoulos ◽  
E A P Croydon
Keyword(s):  
Rheumatoid Arthritis ◽  
Comparative Study ◽  
Crossover Study ◽  
Grip Strength ◽  
Analgesic Activity ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Single Blind ◽  
Blind Crossover Study ◽  
Articular Index

A single-blind crossover study of two non-steroidal anti-inflammatory drugs, nabumetone (1000 mg/day) and naproxen (500 mg/day) was performed in thirty patients suffering from definite or classical rheumatoid arthritis. Nabumetone significantly improved the various parameters assessed, while this was not observed with naproxen. The superiority of nabumetone over naproxen appeared for the anti-inflammatory activity (e.g. E.S.R., articular index, P.I.P. joint circumference, grip strength) as well as for the analgesic activity (patient's opinion). The clinical tolerance appeared equally good for both drugs.

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