Faculty of 1000 evaluation for Effects of vitamin C and vitamin D administration on mood and distress in acutely hospitalized patients.

Nowadays, due to Covid-19 pandemic circumstance, numerous individuals are Staying from home. Understudy is additionally concern with the online class from home, because of which all physical movement of all individual has been stopped. Medoroga is one of the dominating metabolic problems and driving reason for mortality. Numerous patients with Covid infection 2019 (COVID-19) have identified with the metabolic disorder during the lockdown. The general wellbeing proposes (Work from Home, requests, gyms, terminations of garden and wellness focuses) to forestall Covid-19 spread can possibly decrease day by day physical movement. Ideas of Agni, Prakriti, strategy for victualing ought to be given equivalent consideration while choosing ones dietary and exercise routine to turn away/control Medoroga (STHAULYA). Organizing of diet is generally important to support insusceptibility. According to numerous investigates to give valuable pabulum which contains Zinc, Vitamin C, Vitamin D and invulnerability. It is practically equivalent to Medoroga referenced in Ayurveda compositions. Strick likeness outwardly inspected in both customary arrangement of medication and Ayurveda while portraying its causative components, outcomes and preventive part of exercise and diet in its administration. Striking is outwardly analyzed in both Traditional arrangements of medication and Ayurveda depicting its causative factors, and preventive capacity of movement and diet in its pandemic Covid-19.

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A cost-effective preventative approach to potentially save lives in the coronavirus pandemic, jointly using Vitamin D, Curcumin, and Vitamin C. Authors Bakare T A and Soar J S

10.31232/osf.io/jgf6e ◽

2020 ◽

Author(s):

Jagjit S Soar

Keyword(s):

Vitamin D ◽

Vitamin C ◽

Cost Effective ◽

Risk Groups ◽

The Elderly ◽

Pharmaceutical Drugs ◽

Over The Counter ◽

Literature Searches ◽

Pharmaceutical Agents ◽

And Control

he current COVID-19 pandemic now believed to be based on the mutation of the SARS-CoV virus (first reported in 2002) to SARS-CoV-2 emerging in 2019, is naturally causing extreme worry and concern around the world with sometimes mixed and incoherent messages on how to deal with it. There is a plethora of information from previous epidemics caused by other coronaviruses such as severe acute respiratory syndrome, SARS (2002) and Middle East respiratory syndrome MERS (2012) from which we can extrapolate guidance on how to deal with the current pandemic. In the current absence of specific pharmaceutical agents, we propose assessing the extended tools that we already possess in our biological armoury to combat, prevent and control the spread of this virus. Using a set of precise criteria to locate such possible contenders, we conducted literature searches to find compounds that met these criteria. We have now reduced this to a shortlist of three agents that may be the best candidates. We propose vitamin C, vitamin D and Curcumin fit our criteria well. These compounds are widely available to the general public. They are available online and over-the-counter as supplements. Otherwise healthy individuals are safely able to self-administer these agents as a prophylactic to protect themselves and to enhance their immune response. This would be especially desirable for the elderly and at risk groups. These agents can also be used as adjunct therapy, particularly for those who may have early symptoms. This preventative therapy could be implemented whilst awaiting specific pharmaceutical drugs to emerge as a treatment for COVID-19. Our suggested compounds are a highly cost-effective way to potentially reduce the mortality that is regretfully mounting as a result of COVID-19 infection. The biological mode of action and the dosing of these compounds are summarised.

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Stellenwert komplementärer Supportivtherapie bei immunsupprimierten onkologischen Patienten – Eine Kasuistik

Erfahrungsheilkunde ◽

10.1055/a-1263-2875 ◽

2020 ◽

Vol 69 (05) ◽

pp. 280-284

Author(s):

Peter Holzhauer ◽

Uwe Gröber ◽

Klaus Kisters

Keyword(s):

Vitamin D ◽

Vitamin C ◽

Checkpoint Inhibition

ZusammenfassungDie hochdosierte parenterale Applikation von Vitamin C ist eine von zahlreichen komplementärmedizinischen Methoden, die häufig zur Behandlung von tumorassoziierter Fatigue-Symptomatik und als komplementäre Supportivtherapie – auch jetzt in der Phase der COVID-19-Pandemie – zur Immunstimulation und als antivirale Option eingesetzt wird. Die hier vorgestellte Kasuistik beschreibt neben einer folgenreichen Wechselwirkung dieser medikamentösen supportiven Therapie mit einem Hightech-Medizinprodukt auch moderne konventionelle Therapieoptionen beim triple-negativen Mammakarzinom. Dabei kommen verschiedene immunrelevante Mikronährstoffe zum Einsatz, die einerseits die moderne Checkpoint-Inhibition mit Atezolizumab unterstützen und andererseits eine möglichst optimale Abwehrlage in der Phase der Pandemie gewährleisten sollen. Aktuelle Daten wurden zu dieser Thematik gerade für Selen und Vitamin D publiziert.

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Vitamin D supplementation, COVID-19 and disease severity: a meta-analysis

QJM ◽

10.1093/qjmed/hcab009 ◽

2021 ◽

Cited By ~ 1

Author(s):

K Shah ◽

D Saxena ◽

D Mavalankar

Keyword(s):

Vitamin D ◽

Randomized Controlled Trials ◽

Usual Care ◽

Odds Ratio ◽

Meta Analysis ◽

Vitamin D Supplementation ◽

Hospitalized Patients ◽

Controlled Trials ◽

Randomized Controlled

Abstract Objective: Current meta-analysis aims to understand the effect of oral supplementation of vitamin D on intensive care unit (ICU) requirement and mortality in hospitalized COVID-19 patients. Methods: Databases PubMed, preprint servers, and google scholar were searched from December 2019 to December 2020. Authors searched for the articles assessing role of vitamin D supplementation on COVID-19. Cochrane RevMan tool was used for quantitative assessment of the data, where heterogeneity was assessed using I2 and Q statistics and data was expressed using odds ratio with 95% confidence interval. Results: Final meta-analysis involved pooled data of 532 hospitalized patients (189 on vitamin D supplementation and 343 on usual care/placebo) of COVID-19 from three studies (Two randomized controlled trials, one retrospective case-control study). Statistically (p<0.0001) lower ICU requirement was observed in patients with vitamin D supplementation as compared to patients without supplementations (odds ratio: 0.36; 95% CI: 0.210-0.626). However, it suffered from significant heterogeneity, which reduced after sensitivity analysis. In case of mortality, vitamin D supplements has comparable findings with placebo treatment/usual care (odds ratio: 0.93; 95% CI: 0.413-2.113; p=0.87). The studies did not show any publication bias and had fair quality score. Subgroup analysis could not be performed due to limited number of studies and hence dose and duration dependent effect of vitamin D could not be evaluated. Conclusions: Although the current meta-analysis findings indicate potential role of vitamin D in improving COVID-19 severity in hospitalized patients, more robust data from randomized controlled trials are needed to substantiate its effects on mortality.

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