Faculty Opinions recommendation of Limited clinical benefit of minority K103N and Y181C-variant detection in addition to routine genotypic resistance testing in antiretroviral therapy-naive patients.

2014 ◽  
Author(s):  
Jonathan Schapiro
Keyword(s):  
Antiretroviral Therapy ◽  
Clinical Benefit ◽  
Resistance Testing ◽  
Genotypic Resistance ◽  
Genotypic Resistance Testing ◽  
Variant Detection

scholarly journals Limited clinical benefit of minority K103N and Y181C-variant detection in addition to routine genotypic resistance testing in antiretroviral therapy-naive patients

AIDS ◽  
2014 ◽  
Vol 28 (15) ◽  
pp. 2231-2239 ◽  
Author(s):  
Karin J. Metzner ◽  
Alexandra U. Scherrer ◽  
Viktor von Wyl ◽  
Jürg Böni ◽  
Sabine Yerly ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Clinical Benefit ◽  
Resistance Testing ◽  
Genotypic Resistance ◽  
Genotypic Resistance Testing ◽  
Variant Detection

Phenotypic or genotypic resistance testing for choosing antiretroviral therapy after treatment failure: a randomized trial

AIDS ◽  
2002 ◽  
Vol 16 (5) ◽  
pp. 727-736 ◽  
Author(s):  
Jean-Luc Meynard ◽  
Muriel Vray ◽  
Laurence Morand-Joubert ◽  
Esther Race ◽  
Diane Descamps ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Treatment Failure ◽  
Randomized Trial ◽  
Resistance Testing ◽  
Genotypic Resistance ◽  
Genotypic Resistance Testing

scholarly journals Replicative phenotyping adds value to genotypic resistance testing in heavily pre-treated HIV-infected individuals - the Swiss HIV Cohort Study

2011 ◽  
Vol 9 (1) ◽  
pp. 14 ◽  
Author(s):  
Jan Fehr ◽  
Tracy R Glass ◽  
S�verine Louvel ◽  
Fran�ois Hamy ◽  
Hans H Hirsch ◽  
...  
Keyword(s):  
Cohort Study ◽  
Resistance Testing ◽  
Genotypic Resistance ◽  
Genotypic Resistance Testing

scholarly journals Distribution of Human Immunodeficiency Virus Type 1 Protease and Reverse Transcriptase Mutation Patterns in 4,183 Persons Undergoing Genotypic Resistance Testing

2004 ◽  
Vol 48 (8) ◽  
pp. 3122-3126 ◽  
Author(s):  
Soo-Yon Rhee ◽  
Tommy Liu ◽  
Jaideep Ravela ◽  
Matthew J. Gonzales ◽  
Robert W. Shafer
Keyword(s):  
Human Immunodeficiency Virus ◽  
Reverse Transcriptase ◽  
Resistance Testing ◽  
Resistance Mutations ◽  
Genotypic Resistance ◽  
Drug Resistance Mutations ◽  
Genotypic Resistance Testing ◽  
Immunodeficiency Virus

ABSTRACT In a sample of 6,156 sequences from 4,183 persons, the top 30 patterns of protease inhibitor, nucleoside reverse transcriptase (RT) inhibitor, and nonnucleoside RT inhibitor mutations accounted for 55, 46, and 66%, respectively, of sequences with drug resistance mutations. Characterization of the phenotypic and clinical significance of these common patterns may lead to improved treatment recommendations for a large proportion of patients for whom antiretroviral therapy is failing.

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