Faculty Opinions recommendation of Management of precancerous anal intraepithelial lesions in human immunodeficiency virus-positive men who have sex with men: Clinical effectiveness and cost-effectiveness.

2018 ◽  
Author(s):  
Heather Yeo
Keyword(s):  
Human Immunodeficiency Virus ◽  
Cost Effectiveness ◽  
Clinical Effectiveness ◽  
Immunodeficiency Virus ◽  
Sex With Men ◽  
Intraepithelial Lesions

scholarly journals Management of precancerous anal intraepithelial lesions in human immunodeficiency virus-positive men who have sex with men: Clinical effectiveness and cost-effectiveness

Cancer ◽  
2017 ◽  
Vol 123 (23) ◽  
pp. 4709-4719 ◽  
Author(s):  
Ashish A. Deshmukh ◽  
Elizabeth Y. Chiao ◽  
Scott B. Cantor ◽  
Elizabeth A. Stier ◽  
Stephen E. Goldstone ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Cost Effectiveness ◽  
Clinical Effectiveness ◽  
Immunodeficiency Virus ◽  
Sex With Men ◽  
Intraepithelial Lesions

Anal Squamous Intraepithelial Lesions (SILs) in Human Immunodeficiency Virus–Positive Men Who Have Sex With Men: Incidence and Risk Factors of SIL and of Progression and Clearance of Low-Grade SILs

2019 ◽  
Vol 222 (1) ◽  
pp. 62-73 ◽  
Author(s):  
V W Jongen ◽  
O Richel ◽  
E Marra ◽  
M L Siegenbeek van Heukelom ◽  
A van Eeden ◽  
...  
Keyword(s):  
Risk Factors ◽  
Human Immunodeficiency Virus ◽  
Hiv Positive ◽  
Low Grade ◽  
Squamous Intraepithelial Lesions ◽  
Immunodeficiency Virus ◽  
Anal Squamous Intraepithelial Lesions ◽  
Sex With Men ◽  
Intraepithelial Lesions

Abstract Background Human immunodeficiency virus (HIV)–positive men who have sex with men (MSM) are at risk of anal squamous cell carcinoma. Data are limited on the natural history of the precursor to this carcinoma, anal squamous intraepithelial lesions (SILs). Methods HIV-positive MSM were screened for histopathological SILs by means of high-resolution anoscopy (HRA). For participants without SILs at baseline, we estimated the cumulative incidence and risk factors for SILs. For those with low-grade SILs (LSILs) at baseline, the risk of progression to high-grade SILs (HSILs) and the clearance rate were estimated at the lesion level. Results Of 807 men without SILs at baseline, 107 underwent follow-up HRA between 1 to 4.5 years later. At the second visit 18 men (16.8%) showed LSIL, and 25 (23.4%) HSIL. Age was associated with incident LSILs (adjusted odds ratio [aOR], 2.10 per 10-year increase in age; P = .01). Of 393 men with LSILs at baseline, 114 underwent follow-up HRA 0.5 to 2.5 years later. Of the 177 LSILs found at baseline, 87 (49.2%) had cleared at the second visit, and 29 (16.4%) had progressed to HSILs. Conclusion Incident LSILs and HSILs were common during follow-up among HIV-positive MSM without dysplasia at baseline. Among men with LSILs at baseline, nearly half of these lesions cleared, and a small portion progressed.

Virological and Serological Predictors of Anal High-grade Squamous Intraepithelial Lesions Among Human Immunodeficiency Virus–positive Men Who Have Sex With Men

2018 ◽  
Vol 68 (8) ◽  
pp. 1377-1387 ◽  
Author(s):  
Elske Marra ◽  
Matthijs L Siegenbeek van Heukelom ◽  
Annemiek Leeman ◽  
Tim Waterboer ◽  
Chris J L M Meijer ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
High Grade ◽  
Squamous Intraepithelial Lesions ◽  
Immunodeficiency Virus ◽  
Sex With Men ◽  
Intraepithelial Lesions

scholarly journals Trends in human immunodeficiency virus diagnoses among men who have sex with men in North America, Western Europe, and Australia, 2000–2014

2018 ◽  
Vol 28 (12) ◽  
pp. 874-880 ◽  
Author(s):  
Johanna Chapin-Bardales ◽  
Axel J. Schmidt ◽  
Rebecca J. Guy ◽  
John M. Kaldor ◽  
Skye McGregor ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
North America ◽  
Western Europe ◽  
Immunodeficiency Virus ◽  
Sex With Men
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