Faculty Opinions recommendation of Taurine supplementation associated with exercise increases mitochondrial activity and fatty acid oxidation gene expression in the subcutaneous white adipose tissue of obese women.

2020 ◽  
Author(s):  
David Wright
Keyword(s):  
Gene Expression ◽  
Adipose Tissue ◽  
Fatty Acid ◽  
Fatty Acid Oxidation ◽  
White Adipose Tissue ◽  
Acid Oxidation ◽  
Mitochondrial Activity ◽  
Obese Women ◽  
Taurine Supplementation ◽  
Subcutaneous White Adipose Tissue

Taurine supplementation associated with exercise increases mitochondrial activity and fatty acid oxidation gene expression in the subcutaneous white adipose tissue of obese women

2020 ◽  
Author(s):  
Flavia Giolo De Carvalho ◽  
Camila Fernanda Cunha Brandao ◽  
Gabriela Batitucci ◽  
Anderson de Oliveira Souza ◽  
Gustavo Duarte Ferrari ◽  
...  
Keyword(s):  
Gene Expression ◽  
Adipose Tissue ◽  
Fatty Acid ◽  
Fatty Acid Oxidation ◽  
White Adipose Tissue ◽  
Acid Oxidation ◽  
Mitochondrial Activity ◽  
Obese Women ◽  
Taurine Supplementation ◽  
Subcutaneous White Adipose Tissue

Molecular and metabolic profiles suggest that increased lipid catabolism in adipose tissue contributes to leanness in domestic chickens

2014 ◽  
Vol 46 (9) ◽  
pp. 315-327 ◽  
Author(s):  
Bo Ji ◽  
Jesse L. Middleton ◽  
Ben Ernest ◽  
Arnold M. Saxton ◽  
Susan J. Lamont ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Fatty Acid ◽  
Fatty Acid Oxidation ◽  
White Adipose Tissue ◽  
Broiler Chickens ◽  
Acid Oxidation ◽  
Human Obesity ◽  
Insulin Resistant ◽  
Expression Of Genes ◽  
Commercial Broiler

Domestic broiler chickens rapidly accumulate fat and are naturally hyperglycemic and insulin resistant, making them an attractive model for studies of human obesity. We previously demonstrated that short-term (5 h) fasting rapidly upregulates pathways of fatty acid oxidation in broiler chickens and proposed that activation of these pathways may promote leanness. The objective of the current study was to characterize adipose tissue from relatively lean and fatty lines of chickens and determine if heritable leanness in chickens is associated with activation of some of the same pathways induced by fasting. We compared adipose gene expression and metabolite profiles in white adipose tissue of lean Leghorn and Fayoumi breeds to those of fattier commercial broiler chickens. Both lipolysis and expression of genes involved in fatty acid oxidation were upregulated in lean chickens compared with broilers. Although there were strong similarities between the lean lines compared with broilers, distinct expression signatures were also found between Fayoumi and Leghorn, including differences in adipogenic genes. Similarities between genetically lean and fasted chickens suggest that fatty acid oxidation in white adipose tissue is adaptively coupled to lipolysis and plays a role in heritable differences in fatness. Unique signatures of leanness in Fayoumi and Leghorn lines highlight distinct pathways that may provide insight into the basis for leanness in humans. Collectively, our results provide a number of future directions through which to fully exploit chickens as unique models for the study of human obesity and adipose metabolism.

Taurine supplementation in conjunction with exercise modulated cytokines and improved subcutaneous white adipose tissue plasticity in obese women

Amino Acids ◽  
2021 ◽  
Author(s):  
Flavia Giolo De Carvalho ◽  
Camila Fernanda Cunha Brandao ◽  
Vitor Rosetto Muñoz ◽  
Gabriela Batitucci ◽  
Maria Eduarda de Almeida Tavares ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
White Adipose Tissue ◽  
Obese Women ◽  
Taurine Supplementation ◽  
Subcutaneous White Adipose Tissue

scholarly journals Fasting rapidly increases fatty acid oxidation in white adipose tissue of young broiler chickens

Adipocyte ◽  
2016 ◽  
Vol 6 (1) ◽  
pp. 33-39 ◽  
Author(s):  
Emmanuelle Torchon ◽  
Rodney Ray ◽  
Matthew W. Hulver ◽  
Ryan P. McMillan ◽  
Brynn H. Voy
Keyword(s):  
Adipose Tissue ◽  
Fatty Acid ◽  
Fatty Acid Oxidation ◽  
White Adipose Tissue ◽  
Broiler Chickens ◽  
Acid Oxidation

Metabolic and cellular plasticity in white adipose tissue II: role of peroxisome proliferator-activated receptor-α

2005 ◽  
Vol 289 (4) ◽  
pp. E617-E626 ◽  
Author(s):  
Pipeng Li ◽  
Zhengxian Zhu ◽  
Yuyan Lu ◽  
James G. Granneman
Keyword(s):  
Adipose Tissue ◽  
Fatty Acid ◽  
Fatty Acid Oxidation ◽  
White Adipose Tissue ◽  
Mitochondrial Biogenesis ◽  
Gene Profiling ◽  
Acid Oxidation ◽  
Peroxisome Proliferator ◽  
Peroxisome Proliferator Activated Receptor ◽  
Cl 316,243

Chronic activation of adipocyte β-adrenergic receptors induces remodeling of white adipose tissue (WAT) that includes a transient inflammatory response followed by mitochondrial biogenesis, induction of fatty acid oxidation genes, and elevation of tissue oxidative metabolism. Gene profiling experiments of WAT during remodeling induced by the β3-adrenergic receptor agonist CL-316,243 (CL) suggested that peroxisome proliferator-activated receptor-α (Ppara), which is upregulated by CL, might be an important transcriptional regulator of that process. Histological, physiological, and molecular analysis of CL-induced remodeling in wild-type mice and mice lacking Ppara demonstrated that Ppara was important for inducing adipocyte mitochondrial biogenesis and upregulating genes involved in fatty acid oxidation. Furthermore, Ppara-deficient mice exhibited sustained WAT inflammation during CL treatment, indicating that upregulation of Ppara limits proinflammatory signaling during chronic lipolytic activation. Together, these data support the hypothesis that WAT remodeling is an adaptive response to excessive fatty acid mobilization whereby Ppara and its downstream targets elevate fatty acid catabolism and suppress proinflammatory signaling.

scholarly journals Downregulation of lipogenesis and fatty acid oxidation in the subcutaneous adipose tissue of morbidly obese women

Obesity ◽  
2014 ◽  
Vol 22 (9) ◽  
pp. 2032-2038 ◽  
Author(s):  
Teresa Auguet ◽  
Esther Guiu-Jurado ◽  
Alba Berlanga ◽  
Ximena Terra ◽  
Salomé Martinez ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Fatty Acid ◽  
Fatty Acid Oxidation ◽  
Subcutaneous Adipose Tissue ◽  
Acid Oxidation ◽  
Morbidly Obese ◽  
Obese Women ◽  
Subcutaneous Adipose

scholarly journals Fasting rapidly increases fatty acid oxidation in white adipose tissue (269.2)

2014 ◽  
Vol 28 (S1) ◽  
Author(s):  
Emmanuelle Torchon ◽  
Matthew Hulver ◽  
Ryan McMillan ◽  
Brynn Voy
Keyword(s):  
Adipose Tissue ◽  
Fatty Acid ◽  
Fatty Acid Oxidation ◽  
White Adipose Tissue ◽  
Acid Oxidation
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